Growth Metrics

Apogee Therapeutics (APGE) Change in Cash (2022 - 2026)

Apogee Therapeutics (APGE) reported Change in Cash of $320.2 million for Q1 2026, up 1018.33% year-over-year from $28.6 million in Q1 2025, and up 1254.97% on a QoQ basis from $23.6 million in Q4 2025.

Apogee Therapeutics (APGE) has 5 years of Change in Cash data on file, last reported at $320.2 million in Q1 2026.

  • Quarterly Change in Cash rose 1018.33% year-over-year to $320.2 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $344.6 million (up 191.03% YoY) and the FY2025 annual result came in at -$10.5 million, down 144.88% from the prior year.
  • Change in Cash rose to $320.2 million in Q1 2026 per APGE's latest filing, from $23.6 million in the prior quarter.
  • Across five years, Change in Cash topped out at $367.1 million in Q1 2024 and bottomed at -$188.5 million in Q3 2024.
  • The 5-year median for Change in Cash is -$2.4 million (2022), against an average of $29.8 million.
  • Peak annual rise in Change in Cash reached 3577.7% in 2024, while the deepest fall reached 995.41% in 2024.
  • Tracing APGE's Change in Cash over 5 years: stood at $149.3 million in 2022, then sank by 146.65% to -$69.7 million in 2023, then surged by 133.03% to $23.0 million in 2024, then increased by 2.72% to $23.6 million in 2025, then soared by 1254.97% to $320.2 million in 2026.
  • Per Business Quant, the three latest APGE Change in Cash figures stand at $320.2 million (Q1 2026), $23.6 million (Q4 2025), and -$16.6 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Change in Cash (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - 2.44 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn 623.00 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -2.44 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 417.10 Mn
7 Evaxion A 62.56 Bn 62.54 Bn - -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn -153.10 Mn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 53.61 Mn
10 Apogee Therapeutics 5.53 Bn 4.47 Bn - 320.25 Mn

Historic Data

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DateValue
Mar 31, 2026 320.25 Mn
Dec 31, 2025 23.64 Mn
Sep 30, 2025 -16.57 Mn
Jun 30, 2025 17.28 Mn
Mar 31, 2025 -34.87 Mn
Dec 31, 2024 23.01 Mn
Sep 30, 2024 -188.52 Mn
Jun 30, 2024 -178.16 Mn
Mar 31, 2024 367.14 Mn
Dec 31, 2023 -69.66 Mn
Sep 30, 2023 63.20 Mn
Jun 30, 2023 -16.26 Mn
Mar 31, 2023 -10.56 Mn
Dec 31, 2022 149.31 Mn
Sep 30, 2022 -2.39 Mn