According to recent filings covering the 90 days ending December 12, 2025, the three most significant insider holders at Apogee Therapeutics are Chief Executive Officer Michael Thomas Henderson (1.23Mn shares), Chief Medical Officer Carl Dambkowski (271.11K shares), Chief Financial Officer Jane Henderson (194.87K shares).
| Holder | Position | Shares | Report Date |
|---|---|---|---|
| Funds Management Llc Fairmount | 2,048,647 | 01 Apr, 2024 | |
| Nimish P Shah | 1,750,000 | 17 Jul, 2023 | |
| Michael Thomas Henderson | Chief Executive Officer | 1,212,987 | 12 Dec, 2025 |
| Carl Dambkowski | Chief Medical Officer | 271,108 | 05 Dec, 2025 |
| Jane Henderson | Chief Financial Officer | 194,871 | 05 Dec, 2025 |
| Mark C. Mckenna | 20,000 | 16 Dec, 2024 |
* Please note that the shares above only reflect shares from the fund portfolio and the institutional portfolio. Shares from the personal portfolio are excluded from this Institutional Ownership Page. See these insiders' latest transactions here on Insider Page.
| Transaction Date | Insider Name | Security Class | Transaction Type | Shares Traded | Price | Shares Remaining | Ownership | Code |
|---|---|---|---|---|---|---|---|---|
| 10 Dec, 2025 | Michael Thomas Henderson | Common Stock | D | 9,435 | $74.88 | 1,223,552 | D | S |
| 10 Dec, 2025 | Michael Thomas Henderson | Common Stock | D | 10,005 | $75.79 | 1,213,547 | D | S |
| 10 Dec, 2025 | Michael Thomas Henderson | Common Stock | D | 560 | $76.58 | 1,212,987 | D | S |
| 04 Dec, 2025 | Carl Dambkowski | Common Stock | D | 10,900 | $75.00 | 271,108 | D | S |
| 04 Dec, 2025 | Jane Henderson | Common Stock | D | 1,500 | $75.00 | 194,871 | D | S |
| 04 Dec, 2025 | Michael Thomas Henderson | Common Stock | D | 40,000 | $75.01 | 1,232,987 | D | S |
| 25 Nov, 2025 | Jane Henderson | Common Stock | D | 1,500 | $70.00 | 196,371 | D | S |
| 14 Nov, 2025 | Jane Henderson | Common Stock | D | 2,000 | $65.00 | 197,871 | D | S |
| 13 Nov, 2025 | Michael Thomas Henderson | Common Stock | D | 3,340 | $61.93 | 1,289,647 | D | S |
| 13 Nov, 2025 | Michael Thomas Henderson | Common Stock | D | 14,774 | $63.14 | 1,274,873 | D | S |
| 13 Nov, 2025 | Michael Thomas Henderson | Common Stock | D | 1,786 | $63.89 | 1,273,087 | D | S |
| 13 Nov, 2025 | Michael Thomas Henderson | Common Stock | D | 100 | $64.52 | 1,272,987 | D | S |
| 11 Nov, 2025 | Jane Henderson | Common Stock | D | 1,000 | $60.00 | 199,871 | D | S |
| 05 Nov, 2025 | Carl Dambkowski | Common Stock | A | 8,060 | $22.86 | 292,793 | D | M |
| 05 Nov, 2025 | Carl Dambkowski | Common Stock | D | 2,300 | $53.62 | 290,493 | D | S |
| 05 Nov, 2025 | Carl Dambkowski | Common Stock | D | 2,200 | $54.83 | 288,293 | D | S |
| 05 Nov, 2025 | Carl Dambkowski | Common Stock | D | 5,607 | $55.58 | 282,686 | D | S |
| 05 Nov, 2025 | Carl Dambkowski | Common Stock | D | 678 | $56.51 | 282,008 | D | S |
| 01 Oct, 2025 | Carl Dambkowski | Common Stock | A | 2,385 | $22.86 | 289,843 | D | M |
| 01 Oct, 2025 | Carl Dambkowski | Common Stock | D | 5,110 | $39.80 | 284,733 | D | S |