Apogee Therapeutics, Inc. (APGE) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

58,773,731Shares Outstanding

71,400,006Shares held by institutions

$5,987,604,503Value of institutional holdings

121.48%Institutional ownership %

19.24%Shares Changed QoQ

203No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Apogee Therapeutics, Inc. (NASDAQ:APGE) showed up in the 13F filings of 203 institutional investors as of December 2025.

Collectively, these holders controlled 119.0% of Apogee Therapeutics's outstanding shares in December 2025, up from 104.1% in September 2025.
They increased total shares held in Apogee Therapeutics by 18.81% from the prior quarter, while the number of investors in APGE increased 30.13% year over year.
Of these 203 funds, 132 grew their exposure to Apogee Therapeutics, 48 cut back, and 23 maintained positions.
Combined, these investors held 69.94Mn shares in APGE for December 2025, up by 11.07Mn shares quarter on quarter, and up 10.92Mn shares year over year.
Pictet Asset Management Holding SA leads ownership in APGE with 261.05K shares as of December 31, 2025, equal to 0.44% of outstanding shares.
The largest buyers of Apogee Therapeutics for the quarter ending December 2025 were MOODY ALDRICH PARTNERS LLC (11.92K), E Fund Management Co., Ltd. (7.59K), Bayforest Capital Ltd (6.06K), STRS OHIO (1.1K), GF FUND MANAGEMENT CO. LTD. (155).
The largest sellers of Apogee Therapeutics for the quarter ending December 2025 were SG Americas Securities, LLC (63.06K), Pictet Asset Management Holding SA (51.83K), BANQUE PICTET & CIE SA (21.84K), PSP Research LLC (4.48K), Farther Finance Advisors, LLC (19).
Per Business Quant data, the top 10 holders of Apogee Therapeutics for the quarter ending December 2025 are Pictet Asset Management Holding SA (261.05K), MOODY ALDRICH PARTNERS LLC (29.08K), BANQUE PICTET & CIE SA (19.96K), SG Americas Securities, LLC (10.21K), E Fund Management Co., Ltd. (7.59K), Bayforest Capital Ltd (6.06K), STRS OHIO (4.4K), PSP Research LLC (2.5K), GF FUND MANAGEMENT CO. LTD. (1.23K), Sterling Capital Management LLC (289).

203 Institutional Holders

71,400,006 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
VR Adviser, LLC	31 Dec, 2025	8,493,321	0	0.00%	$641,075,869.00
FMR LLC	31 Dec, 2025	8,225,038	1,308,576	18.92%	$620,825,834.00
WELLINGTON MANAGEMENT GROUP LLP	31 Dec, 2025	4,746,585	22,884	0.48%	$358,272,236.00
T. Rowe Price Investment Management, Inc.	31 Dec, 2025	4,288,443	4,287,002	297,501.88%	$323,692.00
BlackRock, Inc.	31 Dec, 2025	3,783,994	1,097,968	40.88%	$285,615,865.00
VANGUARD GROUP INC	31 Dec, 2025	2,857,824	612,193	27.26%	$215,708,556.00
RTW INVESTMENTS, LP	31 Dec, 2025	2,712,097	0	0.00%	$204,709,082.00
PERCEPTIVE ADVISORS LLC	31 Dec, 2025	2,330,651	978,662	72.39%	$175,917,537.00
DRIEHAUS CAPITAL MANAGEMENT LLC	31 Dec, 2025	2,183,704	25,202	1.17%	$164,825,978.00
Janus Henderson Group Plc	31 Dec, 2025	2,062,604	1,576,626	324.42%	$155,697,275.00
Fairmount Funds Management LLC	31 Dec, 2025	2,048,647	0	0.00%	$154,631,876.00
State Street Corp	31 Dec, 2025	1,690,186	34,638	2.09%	$127,575,239.00
Jpmorgan Chase & Co	31 Dec, 2025	1,373,066	-902,396	-39.66%	$103,639,021.00
Affinity Asset Advisors, LLC	31 Dec, 2025	1,234,926	61,500	5.24%	$93,212,214.00
Goldman Sachs Group Inc	31 Dec, 2025	1,130,820	531,204	88.59%	$85,354,294.00
Paradigm Biocapital Advisors LP	31 Dec, 2025	1,123,243	-398,514	-26.19%	$84,782,382.00
ALLIANCEBERNSTEIN L.P.	31 Dec, 2025	1,093,657	-325,475	-22.93%	$82,549,230.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	1,059,085	166,882	18.70%	$79,957,396.00
Avoro Capital Advisors LLC	31 Dec, 2025	1,000,000	1,000,000	0.00%	$75,480,000.00
UBS Group AG	31 Dec, 2025	974,826	175,361	21.93%	$73,579,866.00

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