Apogee Therapeutics, Inc. (APGE) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

57,916,438Shares Outstanding

13,574,303Shares held by institutions

$945,314,461Value of institutional holdings

114.77%Institutional ownership %

17.63%Shares Changed QoQ

199No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Apogee Therapeutics, Inc. (NASDAQ:APGE) currently has 199 active institutional owners and shareholders as of today (December 2025), that have filed 13F forms with the Securities Exchange Commission (SEC).

Institutional ownership in Apogee Therapeutics edged up to 114.8% in December 2025, compared to 103.4% in September 2025.
Institutional share ownership changed by 17.63% QoQ, while the number of institutional owners saw an increase of 26.75% YoY.
During the quarter, 132 institutions bought more Apogee Therapeutics shares, 45 sold shares, and 22 of the 199 total investors held their position steady.
The total number of shares held by institutions in Apogee Therapeutics increased to 66.47Mn as of December 2025, a net change of up by 9.96Mn shares quarter on quarter, and up 8.66Mn shares year over year.
With 8.49Mn shares, VR Adviser, LLC commands the largest institutional position in Apogee Therapeutics as of December 31, 2025, equating to 14.66% of the company.
Among the most significant buyers of Apogee Therapeutics during December 2025 were JANUS HENDERSON GROUP PLC (1.58Mn), T. Rowe Price Investment Management, Inc. (1.55Mn), FMR LLC (1.31Mn), BlackRock, Inc. (1.10Mn), PERCEPTIVE ADVISORS LLC (978.66K).
Leading sellers of Apogee Therapeutics stock in December 2025 included BRAIDWELL LP (863.68K), BARCLAYS PLC (509.12K), CITADEL ADVISORS LLC (402.26K), Paradigm Biocapital Advisors LP (398.51K), ALLIANCEBERNSTEIN L.P. (325.48K).
The top 10 institutional holders of Apogee Therapeutics for the quarter ending December 2025 included VR Adviser, LLC (8.49Mn), FMR LLC (8.23Mn), WELLINGTON MANAGEMENT GROUP LLP (4.75Mn), BlackRock, Inc. (3.78Mn), VANGUARD GROUP INC (2.86Mn), RTW INVESTMENTS, LP (2.71Mn), PERCEPTIVE ADVISORS LLC (2.33Mn), DRIEHAUS CAPITAL MANAGEMENT LLC (2.18Mn), JANUS HENDERSON GROUP PLC (2.06Mn), Fairmount Funds Management LLC (2.05Mn).

199 Institutional Holders

13,574,303 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
VR Adviser, LLC	31 Dec, 2025	8,493,321	0	0.00%	$641,075,869.00
FMR LLC	31 Dec, 2025	8,225,038	1,308,576	18.92%	$620,825,834.00
WELLINGTON MANAGEMENT GROUP LLP	31 Dec, 2025	4,746,585	22,884	0.48%	$358,272,236.00
BlackRock, Inc.	31 Dec, 2025	3,783,994	1,097,968	40.88%	$285,615,865.00
VANGUARD GROUP INC	31 Dec, 2025	2,857,824	612,193	27.26%	$215,708,556.00
RTW INVESTMENTS, LP	31 Dec, 2025	2,712,097	0	0.00%	$204,709,082.00
PERCEPTIVE ADVISORS LLC	31 Dec, 2025	2,330,651	978,662	72.39%	$175,917,537.00
DRIEHAUS CAPITAL MANAGEMENT LLC	31 Dec, 2025	2,183,704	25,202	1.17%	$164,825,978.00
JANUS HENDERSON GROUP PLC	31 Dec, 2025	2,062,604	1,576,626	324.42%	$155,697,275.00
Fairmount Funds Management LLC	31 Dec, 2025	2,048,647	0	0.00%	$154,631,876.00
STATE STREET CORP	31 Dec, 2025	1,690,186	34,638	2.09%	$127,575,239.00
T. Rowe Price Investment Management, Inc.	31 Dec, 2025	1,555,987	1,554,546	107,879.67%	$117,446.00
JPMORGAN CHASE & CO	31 Dec, 2025	1,373,066	235,335	20.68%	$103,639,021.00
Affinity Asset Advisors, LLC	31 Dec, 2025	1,234,926	61,500	5.24%	$93,212,214.00
Paradigm Biocapital Advisors LP	31 Dec, 2025	1,123,243	-398,514	-26.19%	$84,782,382.00
ALLIANCEBERNSTEIN L.P.	31 Dec, 2025	1,093,657	-325,475	-22.93%	$82,549,230.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	1,059,085	166,882	18.70%	$79,957,396.00
UBS Group AG	31 Dec, 2025	974,826	175,361	21.93%	$73,579,866.00
MORGAN STANLEY	31 Dec, 2025	890,264	425,301	91.47%	$67,197,243.00
BANK OF AMERICA CORP /DE/	31 Dec, 2025	793,695	399,783	101.49%	$59,908,098.00

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