AN2 Therapeutics (ANTX) EBITDA (2021 - 2026)

AN2 Therapeutics' (ANTX) quarterly EBITDA came in at -$10.6 million in Q1 2026, up 8.55% year-on-year from -$9.7 million in Q1 2025, and down 13.26% on a QoQ basis from -$9.3 million in Q4 2025.

AN2 Therapeutics (ANTX) EBITDA (2021 - 2026) Analysis & Trends

AN2 Therapeutics (ANTX) has 6 years of EBITDA data on file, last reported at -$10.6 million in Q1 2026.

  • On a quarterly basis, EBITDA rose 8.55% year-over-year to -$10.6 million in Q1 2026; TTM through Mar 2026 was -$37.1 million, a 25.8% increase from a year earlier, with the FY2025 full-year figure at -$38.1 million, up 32.89% from the prior year.
  • EBITDA for Q1 2026 stood at -$10.6 million, down from -$9.3 million in the prior quarter.
  • Over the last five years, EBITDA for ANTX reached as high as -$7.2 million in Q2 2025 and fell as low as -$18.8 million in Q4 2023.
  • Historically, EBITDA has averaged -$12.8 million across 5 years, with a median of -$11.8 million in 2022.
  • Across the five-year window, EBITDA slumped 274.78% in 2022 and soared 54.56% in 2025, its largest moves.
  • Year by year, EBITDA stood at -$12.5 million in 2022, then sank by 50.81% to -$18.8 million in 2023, then jumped by 54.3% to -$8.6 million in 2024, then decreased by 8.35% to -$9.3 million in 2025, then dropped by 13.26% to -$10.6 million in 2026.
  • Per Business Quant data, the three most recent EBITDA figures were -$10.6 million in Q1 2026, -$9.3 million in Q4 2025, and -$10.0 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -27.75 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 249.90 Mn
4 NuCana 279.75 Bn 279.75 Bn - -3.72 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 1.14 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 642.90 Mn
7 Belite Bio 62.51 Bn 62.51 Bn - -32.68 Mn
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 493.00 Mn
9 Revolution Medicines 37.78 Bn 37.78 Bn - -445.22 Mn
10 AN2 Therapeutics 167.57 Mn 167.57 Mn - -10.55 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -10.55 Mn
Dec 31, 2025 -9.32 Mn
Sep 30, 2025 -10.04 Mn
Jun 30, 2025 -7.22 Mn
Mar 31, 2025 -11.54 Mn
Dec 31, 2024 -8.60 Mn
Sep 30, 2024 -14.01 Mn
Jun 30, 2024 -15.88 Mn
Mar 31, 2024 -18.30 Mn
Dec 31, 2023 -18.82 Mn
Sep 30, 2023 -18.18 Mn
Jun 30, 2023 -16.60 Mn
Mar 31, 2023 -16.04 Mn
Dec 31, 2022 -12.48 Mn
Sep 30, 2022 -11.77 Mn
Jun 30, 2022 -10.33 Mn
Mar 31, 2022 -7.68 Mn
Dec 31, 2021 -7.59 Mn
Sep 30, 2021 -6.93 Mn
Jun 30, 2021 -5.00 Mn