AN2 Therapeutics (ANTX) EBITDA (2021 - 2026)

AN2 Therapeutics (ANTX) reported EBITDA of -$10.1 million for Q1 2026, up 5.1% year-over-year from -$9.6 million in Q1 2025, and down 15.75% quarter-over-quarter from -$8.7 million in Q4 2025.

AN2 Therapeutics (ANTX) EBITDA (2021 - 2026) Analysis & Trends

AN2 Therapeutics (ANTX) has 6 years of EBITDA data on file, last reported at -$10.1 million in Q1 2026.

  • EBITDA for Q1 2026 came in at -$10.1 million, up 5.1% year-over-year; the trailing twelve-month figure through Mar 2026 was -$34.6 million (up 23.7% YoY), and the FY2025 annual result was -$35.1 million, up 31.84% from the prior year.
  • EBITDA fell to -$10.1 million in Q1 2026 per ANTX's latest filing, from -$8.7 million in the prior quarter.
  • Over five years, EBITDA peaked at -$6.5 million in Q2 2025 and troughed at -$16.8 million in Q1 2024.
  • A 5-year average of -$11.9 million and a median of -$11.5 million in 2022 frame the typical range for EBITDA.
  • The sharpest annual moves came in 2022 and 2025: EBITDA plunged 280.18% in 2022, then surged 55.32% in 2025.
  • A 5-year view of EBITDA shows it stood at -$11.7 million in 2022, then sank by 41.34% to -$16.5 million in 2023, then soared by 53.92% to -$7.6 million in 2024, then fell by 14.65% to -$8.7 million in 2025, then slipped by 15.75% to -$10.1 million in 2026.
  • Business Quant data shows ANTX's EBITDA at -$10.1 million in Q1 2026, -$8.7 million in Q4 2025, and -$9.3 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Alterity Therapeutics 814,307.08 Bn 814,307.05 Bn - -
2 Belite Bio 55,320.00 Bn 55,320.00 Bn - -26.92 Mn
3 Quantum Biopharma 17,149.72 Bn 17,149.72 Bn - -13.63 Mn
4 Legend Biotech 3,590.00 Bn 3,589.71 Bn 242.10 Mn -19.70 Mn
5 Akari Therapeutics 1,650.72 Bn 1,650.72 Bn - -14.44 Mn
6 Evaxion A 1,522.09 Bn 1,522.07 Bn - -3.82 Mn
7 Psyence Biomedical 229.39 Bn 229.38 Bn - -752,618.00
8 Vertex Pharmaceuticals 113.09 Bn 105.85 Bn 2.59 Bn 1.14 Bn
9 Abivax 90.15 Bn 90.15 Bn - -65.83 Mn
10 AN2 Therapeutics 161.95 Mn 161.95 Mn - -10.09 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -10.09 Mn
Dec 31, 2025 -8.72 Mn
Sep 30, 2025 -9.31 Mn
Jun 30, 2025 -6.49 Mn
Mar 31, 2025 -10.63 Mn
Dec 31, 2024 -7.60 Mn
Sep 30, 2024 -12.61 Mn
Jun 30, 2024 -14.52 Mn
Mar 31, 2024 -16.84 Mn
Dec 31, 2023 -16.50 Mn
Sep 30, 2023 -16.71 Mn
Jun 30, 2023 -15.75 Mn
Mar 31, 2023 -15.12 Mn
Dec 31, 2022 -11.68 Mn
Sep 30, 2022 -11.52 Mn
Jun 30, 2022 -10.32 Mn
Mar 31, 2022 -7.79 Mn
Dec 31, 2021 -7.57 Mn
Sep 30, 2021 -6.95 Mn
Jun 30, 2021 -5.01 Mn