Anaptysbio (ANAB) Net Margin (2016 - 2026)
Anaptysbio (ANAB) posted Net Margin of 206.93% for Q1 2026, down 409.0% on a QoQ basis from 66.97% in Q4 2025, and down 6531.0% year-over-year from 3.22% in Q1 2025.
Anaptysbio (ANAB) Net Margin (2016 - 2026) Analysis & Trends
Anaptysbio's Net Margin history runs 11 years deep, the most recent figure standing at 206.93% for Q1 2026.
- Quarterly Net Margin fell 6531.0% year-over-year to 206.93% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 15.15% (up 12471.0% YoY) and the FY2025 annual result came in at 5.38%, up 12022.0% from the prior year.
- Net Margin was 206.93% for Q1 2026 at Anaptysbio, down from 66.97% in the prior quarter.
- Across five years, Net Margin topped out at 66.97% in Q4 2025 and bottomed at 5811.96% in Q1 2022.
- A 5-year average of 1312.91% and a median of 454.36% in 2022 frame the typical range for Net Margin.
- Annual changes were most pronounced in 2022 — Net Margin plunged 545825 bps — and 2024, when it jumped 394039 bps.
- Anaptysbio's Net Margin stood at 454.36% in 2022, then retreated by 3 bps to 468.27% in 2023, then surged by 107 bps to 34.87% in 2024, then soared by 92 bps to 66.97% in 2025, then slumped by 409 bps to 206.93% in 2026.
- Business Quant data shows ANAB's Net Margin at 206.93% in Q1 2026, 66.97% in Q4 2025, and 30.23% in Q3 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 67,072.09 Bn | 67,072.09 Bn | - | - |
| 2 | Nanobiotix | 1,894.61 Bn | 1,894.55 Bn | - | - |
| 3 | Akari Therapeutics | 1,014.18 Bn | 1,014.18 Bn | - | - |
| 4 | BeOne Medicines | 471.64 Bn | 466.85 Bn | 1.35 Bn | 15.02% |
| 5 | Vertex Pharmaceuticals | 121.72 Bn | 114.47 Bn | 2.59 Bn | 34.53% |
| 6 | Regeneron Pharmaceuticals | 68.28 Bn | 59.52 Bn | 3.31 Bn | 20.17% |
| 7 | Belite Bio | 61.40 Bn | 61.40 Bn | - | - |
| 8 | Argenx Se | 56.94 Bn | 56.94 Bn | 1.18 Bn | 28.20% |
| 9 | Revolution Medicines | 37.37 Bn | 37.37 Bn | - | - |
| 10 | Anaptysbio | 1.55 Bn | 1.27 Bn | - | -206.93% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -206.93% |
| Dec 31, 2025 | 66.97% |
| Sep 30, 2025 | 30.23% |
| Jun 30, 2025 | -173.52% |
| Mar 31, 2025 | -141.62% |
| Dec 31, 2024 | 34.87% |
| Sep 30, 2024 | -219.01% |
| Jun 30, 2024 | -425.30% |
| Mar 31, 2024 | -612.01% |
| Dec 31, 2023 | -468.27% |
| Sep 30, 2023 | -1,124.41% |
| Jun 30, 2023 | -1,151.59% |
| Mar 31, 2023 | -4,552.40% |
| Dec 31, 2022 | -454.36% |
| Sep 30, 2022 | -2,909.44% |
| Jun 30, 2022 | -4,200.74% |
| Mar 31, 2022 | -5,811.96% |
| Dec 31, 2021 | -3,177.74% |
| Sep 30, 2021 | -168.43% |
| Jun 30, 2021 | -131.02% |