Anaptysbio (ANAB) Net Margin (2016 - 2026)
Anaptysbio (ANAB) recorded Net Margin of -206.93% in Q1 2026, down 65.31 percentage points from -141.62% a year earlier and down 252.77 percentage points from the prior quarter.
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Analysis
Anaptysbio (ANAB) Net Margin (2016 - 2026) Analysis & Trends
On a TTM basis, Anaptysbio's Net Margin came in at -11.53% as of Mar 31, 2026, up 114.17 percentage points year-over-year; for FY2025, it came in at -5.64%, up 153.46 percentage points from FY2024.
- Annual Net Margin has increased for three straight years, with a five-year change of +20.93 percentage points (FY2020 to FY2025).
- Across earlier years, Net Margin came in at -159.10% in FY2024 (+794.55 pp), -953.66% in FY2023 (+297.67 pp), -1251.33% in FY2022 (-1159.84 pp) and -91.49% in FY2021 (-64.91 pp).
- The Q1 2026 figure is the lowest quarterly Net Margin since Q2 2024.
- On a year-over-year basis, Net Margin rose in seven of the last eight quarters, with an average year-over-year change of +380.24 percentage points.
- Peak year-over-year performance for Net Margin in the last five years was a gain of 2830.43 percentage points in Q4 2022, against a drop of 3576.14 percentage points in Q1 2022 at the low end.
- Per Business Quant, the preceding three quarters came in at 45.83% (Q4 2025), 19.80% (Q3 2025) and -173.52% (Q2 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 21.86% |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 21.27% |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | -8.04% |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | 22.61% |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 18.81% |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 23.62% |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | -134.51% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | -1.65% |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 32.99% |
| 10 | Anaptysbio | 1.47 Bn | 362.02 Mn | - | -206.93% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Mar 31, 2026 | -206.93% |
| Dec 31, 2025 | 45.83% |
| Sep 30, 2025 | 19.80% |
| Jun 30, 2025 | -173.52% |
| Mar 31, 2025 | -141.62% |
| Dec 31, 2024 | -50.53% |
| Sep 30, 2024 | -109.44% |
| Jun 30, 2024 | -425.30% |
| Mar 31, 2024 | -612.01% |
| Dec 31, 2023 | -468.75% |
| Sep 30, 2023 | -1,124.41% |
| Jun 30, 2023 | -1,151.59% |
| Mar 31, 2023 | -3,220.89% |
| Dec 31, 2022 | -387.97% |
| Sep 30, 2022 | -2,591.03% |
| Jun 30, 2022 | -2,677.14% |
| Mar 31, 2022 | -3,737.63% |
| Dec 31, 2021 | -3,218.40% |
| Sep 30, 2021 | -31.91% |
| Jun 30, 2021 | -1.43% |
API Access
Anaptysbio Net Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=net-margin&ticker=ANAB&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "net-margin", "ticker": "ANAB", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=net-margin&ticker=ANAB&period=max&api_key=YOUR_API_KEY");
const data = await res.json();