Anaptysbio ANAB Institutional Ownership

NASDAQ ANAB

$48.25 +0.31 (+0.65%)

As of: Oct 22, 2026 · 11:55 AM EDT

Institutions by Trading Activity

213 Institutions

Increased 120 56.3%

Unchanged 29 13.6%

Reduced 64 30.0%

Ownership Statistics

13F · as of 30 Jun, 2026

Institutional Ownership

—

13F totals exceed reported shares outstanding

Shares Held by Institutions

30.11Mn

of 29.03Mn outstanding

▲+6.58% QoQ

Shares Outstanding

29.03Mn

Institutional Investors

213

filed 13F for Jun 2026

▲+5 vs prior quarter

Net Shares Added (QoQ)

+1.86Mn

accumulated since last quarter

Value of Holdings

$1.37Bn

reported market value

Shares Owned by Institutions

Shares held % of outstanding

Latest —

Average ownership —

Peak ownership —

Shares Purchased/Sold by Institutions

Accumulated Distributed

Latest quarter —

Net over range —

Accumulating quarters —

Ownership Summary

Updated Oct 11, 2026

Anaptysbio, Inc (NASDAQ:ANAB) had 213 institutional holders reporting a position on Form 13F for the quarter ended June 30, 2026.

Total shares held in Anaptysbio rose 6.58% from Q1 2026, while the number of holders rose 46.90% from Q2 2025.
Among the 213 holders of Anaptysbio, 120 added to their positions, 64 reduced their stakes and 29 left their positions unchanged.
In total, institutional investors held 30.11Mn shares of Anaptysbio at the end of Q2 2026, up 1.86Mn from the prior quarter and down 4.67Mn from a year earlier.
EcoR1 Capital, LLC was the top holder of Anaptysbio as of June 30, 2026, with 7.88Mn shares.
Among existing holders, the largest additions to Anaptysbio in Q2 2026 came from Woodline Partners LP (+372.76K shares), Millennium Management LLC (+331.74K shares), State Street Corp (+293.75K shares), Apis Capital Advisors, LLC (+259K shares) and Goldman Sachs Group Inc (+251.33K shares).
On the other side, among holders that kept a position in Anaptysbio, the largest reductions in Q2 2026 came from Morgan Stanley (-736.81K shares), FMR LLC (-232.19K shares), Two Sigma Investments, LP (-202.09K shares), Affinity Asset Advisors, LLC (-113.89K shares) and BNP Paribas Financial Markets (-89K shares).
Per Business Quant, the top 10 investors in ANAB for the quarter ended June 30, 2026 were EcoR1 Capital, LLC (7.88Mn shares), BlackRock, Inc. (1.84Mn shares), Tang Capital Management LLC (1.33Mn shares), State Street Corp (1.29Mn shares), Vanguard Capital Management LLC (906.23K shares), Affinity Asset Advisors, LLC (826.11K shares), Sanofi (821.92K shares), Millennium Management LLC (807.32K shares), Woodline Partners LP (717.01K shares) and 683 Capital Management, LLC (660K shares).

Form 13F Holdings

213 Institutional Holders

Report period 30 Jun, 2026

Total shares held 30.11Mn

Of outstanding —

#	Institution	CIK	Shares Held	% of Outstanding	Change (QoQ)	Change (%)	Value (USD)
1	EcoR1 Capital, LLC	0001587114	7,880,094	27.14%	0	0.00%	$531.91Mn
2	BlackRock, Inc.	0002012383	1,844,049	6.35%	▲162,669	+9.67%	$124.47Mn
3	TANG CAPITAL MANAGEMENT LLC	0001232621	1,330,879	4.58%	0	0.00%	$89.83Mn
4	State Street Corp	0000093751	1,286,194	4.43%	▲293,749	+29.60%	$86.82Mn
5	VANGUARD CAPITAL MANAGEMENT LLC	0002100119	906,233	3.12%	▲53,082	+6.22%	$61.17Mn
6	Affinity Asset Advisors, LLC	0001773195	826,109	2.85%	▼113,891	-12.12%	$55.76Mn
7	Sanofi	0001121404	821,917	2.83%	0	0.00%	$55.48Mn
8	MILLENNIUM MANAGEMENT LLC	0001273087	807,316	2.78%	▲331,744	+69.76%	$54.49Mn
9	Woodline Partners LP	0001784547	717,014	2.47%	▲372,758	+108.28%	$48.40Mn
10	683 Capital Management, LLC	0001404574	660,000	2.27%	▲35,000	+5.60%	$44.55Mn
11	GEODE CAPITAL MANAGEMENT, LLC	0001214717	637,873	2.20%	▲117,632	+22.61%	$43.06Mn
12	Palo Alto Investors LP	0001306923	603,489	2.08%	▼34,672	-5.43%	$40.74Mn
13	Goldman Sachs Group Inc	0000886982	584,070	2.01%	▲251,327	+75.53%	$39.42Mn
14	First Light Asset Management, LLC	0001600004	582,004	2.00%	▲16,573	+2.93%	$39.29Mn
15	D. E. Shaw & Co., Inc.	0001009207	539,666	1.86%	▼39,630	-6.84%	$36.43Mn
16	VANGUARD PORTFOLIO MANAGEMENT LLC	0002100121	527,858	1.82%	▲7,988	+1.54%	$35.63Mn
17	APIS CAPITAL ADVISORS, LLC	0001386892	497,000	1.71%	▲259,000	+108.82%	$33.55Mn
18	Sofinnova Investments, Inc.	0001631134	493,536	1.70%	▲245,283	+98.80%	$33.31Mn
19	ARROWSTREET CAPITAL, LIMITED PARTNERSHIP	0001164508	488,651	1.68%	▼3,469	-0.70%	$32.98Mn
20	Nuveen, LLC	0001871926	420,664	1.45%	▲104,599	+33.09%	$28.39Mn

Showing 1 to 20 of 213 holders