Amylyx Pharmaceuticals AMLX
NASDAQ AMLX
$33.19 -0.69 (-2.04%)
As of: Sep 9, 2026 · 12:04 PM EDT

Amylyx Pharmaceuticals (AMLX) Net Margin (2021 - 2024)

Amylyx Pharmaceuticals (AMLX) posted Net Margin of 4011.01% for Q4 2024, up 77.05% on a QoQ basis from 17476.92% in Q3 2024, and down 401516.0% year-over-year from N/an in Q1 2024.

Analysis

Amylyx Pharmaceuticals (AMLX) Net Margin (2021 - 2024) Analysis & Trends

Amylyx Pharmaceuticals has reported Net Margin for 4 years, with the latest figure at 4011.01% in Q4 2024.

  • On a quarterly basis, Net Margin fell 401516.0% year-over-year to 4011.01% in Q4 2024; TTM through Sep 2025 was 13557.55%, a 1368835.0% increase from a year earlier, with the FY2024 full-year figure at 273.1%, down 28598.0% from the prior year.
  • Net Margin was 4011.01% for Q4 2024 at Amylyx Pharmaceuticals, up from 17476.92% in the prior quarter.
  • The five-year high for Net Margin was 22.47% in Q2 2023, with the low at 17476.92% in Q3 2024.
  • Average Net Margin over 4 years is 4780.08%, with a median of 200.15% recorded in 2022.
  • The sharpest annual moves came in 2023 and 2024: Net Margin soared 1560179 bps in 2023, then tumbled 1749727 bps in 2024.
  • Over 4 years, Net Margin stood at 8120.0% in 2021, then jumped by 98 bps to 200.15% in 2022, then soared by 102 bps to 4.16% in 2023, then sank by 96614 bps to 4011.01% in 2024.
  • The last three Net Margin figures came in at 4011.01% (Q4 2024), 17476.92% (Q3 2024), and 7106.55% (Q2 2024), per Business Quant data.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Margin (Qtr)
1 Amgen 211.88 Bn 197.89 Bn 7.24 Bn 23.62%
2 Gilead Sciences 181.55 Bn 178.37 Bn 6.22 Bn -134.51%
3 Vertex Pharmaceuticals 132.31 Bn 124.45 Bn 2.84 Bn 32.99%
4 Regeneron Pharmaceuticals 82.51 Bn 74.52 Bn 3.93 Bn 30.23%
5 Argenx Se 61.54 Bn 56.36 Bn 1.37 Bn 31.16%
6 Moderna 54.69 Bn 49.55 Bn 52.00 Mn -539.31%
7 Alnylam Pharmaceuticals 34.07 Bn 30.76 Bn 992.69 Mn 12.74%
8 Biogen 31.41 Bn 30.12 Bn 1.96 Bn 3.56%
9 Roivant Sciences 30.10 Bn 30.10 Bn 1.16 Mn -20,152.98%
10 Amylyx Pharmaceuticals 3.69 Bn 3.69 Bn - -
Historic Data

Historic Data

Download Data
DateValue
Dec 31, 2024 -4,011.01%
Sep 30, 2024 -17,476.92%
Jun 30, 2024 -7,106.55%
Mar 31, 2024 -134.01%
Dec 31, 2023 4.16%
Sep 30, 2023 20.35%
Jun 30, 2023 22.47%
Mar 31, 2023 2.20%
Dec 31, 2022 -200.15%
Sep 30, 2022 -15,581.45%
Sep 30, 2021 -8,120.00%