Amylyx Pharmaceuticals (AMLX) Enterprise Value (2021 - 2026)

Amylyx Pharmaceuticals' (AMLX) quarterly Enterprise Value came in at -$279.8 million in Q1 2026, down 37.1% year-on-year from -$444.8 million in Q1 2025, and up 11.74% quarter-over-quarter from -$317.0 million in Q4 2025.

Amylyx Pharmaceuticals (AMLX) Enterprise Value (2021 - 2026) Analysis & Trends

Amylyx Pharmaceuticals' Enterprise Value history runs 6 years deep, the most recent figure standing at -$279.8 million for Q1 2026.

  • On a quarterly basis, Enterprise Value fell 37.1% year-over-year to -$279.8 million in Q1 2026; TTM through Mar 2026 was -$279.8 million, a 37.1% decrease from a year earlier, with the FY2025 full-year figure at -$317.0 million, down 79.59% from the prior year.
  • Enterprise Value improved to -$279.8 million in Q1 2026 per AMLX's latest filing, from -$317.0 million in the prior quarter.
  • Across five years, Enterprise Value topped out at -$162.6 million in Q3 2022 and bottomed at -$373.3 million in Q1 2024.
  • The 5-year median for Enterprise Value is -$309.8 million (2024), against an average of -$283.6 million.
  • Across the five-year window, Enterprise Value tumbled 260.96% in 2022 and jumped 52.47% in 2024, its largest moves.
  • Year by year, Enterprise Value stood at -$346.9 million in 2022, then slipped by 7.04% to -$371.4 million in 2023, then soared by 52.47% to -$176.5 million in 2024, then tumbled by 79.59% to -$317.0 million in 2025, then rose by 11.74% to -$279.8 million in 2026.
  • Per Business Quant, the three latest AMLX Enterprise Value figures stand at -$279.8 million (Q1 2026), -$317.0 million (Q4 2025), and -$344.0 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Enterprise Value (Qtr)
1 Haleon 87.22 Bn 85.35 Bn - -1.86 Bn
2 Teva Pharmaceutical Industries 39.60 Bn 35.87 Bn 1.97 Bn -3.74 Bn
3 Zoetis 31.46 Bn 29.52 Bn 1.62 Bn -1.94 Bn
4 Takeda Pharmaceutical 26.49 Bn 22.44 Bn 4.39 Bn -4.05 Bn
5 United Therapeutics 23.03 Bn 20.88 Bn 648.10 Mn -2.15 Bn
6 Universe Pharmaceuticals 23.03 Bn -10.56 Bn - -33.59 Bn
7 Viatris 20.90 Bn 19.09 Bn 1.16 Bn -1.80 Bn
8 Neurocrine Biosciences 17.50 Bn 16.19 Bn 800.70 Mn -1.32 Bn
9 Elanco Animal Health 12.33 Bn 11.91 Bn 785.00 Mn -428.00 Mn
10 Amylyx Pharmaceuticals 1.94 Bn 1.94 Bn - -279.77 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -279.77 Mn
Dec 31, 2025 -316.98 Mn
Sep 30, 2025 -343.99 Mn
Jun 30, 2025 -180.83 Mn
Mar 31, 2025 -204.07 Mn
Dec 31, 2024 -176.50 Mn
Sep 30, 2024 -234.40 Mn
Jun 30, 2024 -309.81 Mn
Mar 31, 2024 -373.29 Mn
Dec 31, 2023 -371.36 Mn
Sep 30, 2023 -355.05 Mn
Jun 30, 2023 -357.28 Mn
Mar 31, 2023 -345.67 Mn
Dec 31, 2022 -346.95 Mn
Sep 30, 2022 -162.59 Mn
Jun 30, 2022 -206.68 Mn
Mar 31, 2022 -255.21 Mn
Dec 31, 2021 -96.12 Mn