Amylyx Pharmaceuticals (AMLX) Enterprise Value (2021 - 2026)
Amylyx Pharmaceuticals (AMLX) recorded quarterly Enterprise Value of -$279.8 million in Q1 2026, up 11.74% quarter-over-quarter from -$317.0 million in Q4 2025, and down 37.1% on a YoY basis from -$444.8 million in Q1 2025.
Amylyx Pharmaceuticals (AMLX) Enterprise Value (2021 - 2026) Analysis & Trends
Amylyx Pharmaceuticals' Enterprise Value history runs 6 years deep, the most recent figure standing at -$279.8 million for Q1 2026.
- In Q1 2026, Enterprise Value fell 37.1% year-over-year to -$279.8 million; the TTM figure through Mar 2026 stood at -$279.8 million (down 37.1% YoY), while the FY2025 annual figure was -$317.0 million, down 79.59% from the prior year.
- Enterprise Value was -$279.8 million for Q1 2026 at Amylyx Pharmaceuticals, up from -$317.0 million in the prior quarter.
- In the past five years, Enterprise Value ranged from a high of -$162.6 million in Q3 2022 to a low of -$373.3 million in Q1 2024.
- Historically, Enterprise Value has averaged -$283.6 million across 5 years, with a median of -$309.8 million in 2024.
- The sharpest annual moves came in 2022 and 2024: Enterprise Value tumbled 260.96% in 2022, then surged 52.47% in 2024.
- A 5-year view of Enterprise Value shows it stood at -$346.9 million in 2022, then slipped by 7.04% to -$371.4 million in 2023, then soared by 52.47% to -$176.5 million in 2024, then sank by 79.59% to -$317.0 million in 2025, then rose by 11.74% to -$279.8 million in 2026.
- The last three Enterprise Value figures came in at -$279.8 million (Q1 2026), -$317.0 million (Q4 2025), and -$344.0 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Enterprise Value (Qtr) |
|---|---|---|---|---|---|
| 1 | Teva Pharmaceutical Industries | 39.72 Bn | 35.98 Bn | 1.97 Bn | -3.74 Bn |
| 2 | Zoetis | 34.61 Bn | 32.67 Bn | 1.62 Bn | -1.94 Bn |
| 3 | United Therapeutics | 24.07 Bn | 21.91 Bn | 648.10 Mn | -2.15 Bn |
| 4 | Aurora Cannabis | 16.98 Bn | 16.91 Bn | 33.43 Mn | -77.77 Mn |
| 5 | Neurocrine Biosciences | 16.64 Bn | 15.32 Bn | 800.70 Mn | -1.32 Bn |
| 6 | Elanco Animal Health | 12.19 Bn | 11.76 Bn | 785.00 Mn | -428.00 Mn |
| 7 | Alkermes | 7.37 Bn | 6.86 Bn | -116.06 Mn | -511.86 Mn |
| 8 | Hims & Hers Health | 6.62 Bn | 5.87 Bn | 396.79 Mn | -750.88 Mn |
| 9 | Lantheus Holdings | 6.47 Bn | 5.97 Bn | 230.92 Mn | -498.58 Mn |
| 10 | Amylyx Pharmaceuticals | 1.51 Bn | 1.51 Bn | - | -279.77 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -279.77 Mn |
| Dec 31, 2025 | -316.98 Mn |
| Sep 30, 2025 | -343.99 Mn |
| Jun 30, 2025 | -180.83 Mn |
| Mar 31, 2025 | -204.07 Mn |
| Dec 31, 2024 | -176.50 Mn |
| Sep 30, 2024 | -234.40 Mn |
| Jun 30, 2024 | -309.81 Mn |
| Mar 31, 2024 | -373.29 Mn |
| Dec 31, 2023 | -371.36 Mn |
| Sep 30, 2023 | -355.05 Mn |
| Jun 30, 2023 | -357.28 Mn |
| Mar 31, 2023 | -345.67 Mn |
| Dec 31, 2022 | -346.95 Mn |
| Sep 30, 2022 | -162.59 Mn |
| Jun 30, 2022 | -206.68 Mn |
| Mar 31, 2022 | -255.21 Mn |
| Dec 31, 2021 | -96.12 Mn |