Amylyx Pharmaceuticals (AMLX) Enterprise Value (2021 - 2026)

Amylyx Pharmaceuticals (AMLX) recorded quarterly Enterprise Value of -$279.8 million in Q1 2026, up 11.74% quarter-over-quarter from -$317.0 million in Q4 2025, and down 37.1% on a YoY basis from -$444.8 million in Q1 2025.

Amylyx Pharmaceuticals (AMLX) Enterprise Value (2021 - 2026) Analysis & Trends

Amylyx Pharmaceuticals' Enterprise Value history runs 6 years deep, the most recent figure standing at -$279.8 million for Q1 2026.

  • In Q1 2026, Enterprise Value fell 37.1% year-over-year to -$279.8 million; the TTM figure through Mar 2026 stood at -$279.8 million (down 37.1% YoY), while the FY2025 annual figure was -$317.0 million, down 79.59% from the prior year.
  • Enterprise Value was -$279.8 million for Q1 2026 at Amylyx Pharmaceuticals, up from -$317.0 million in the prior quarter.
  • In the past five years, Enterprise Value ranged from a high of -$162.6 million in Q3 2022 to a low of -$373.3 million in Q1 2024.
  • Historically, Enterprise Value has averaged -$283.6 million across 5 years, with a median of -$309.8 million in 2024.
  • The sharpest annual moves came in 2022 and 2024: Enterprise Value tumbled 260.96% in 2022, then surged 52.47% in 2024.
  • A 5-year view of Enterprise Value shows it stood at -$346.9 million in 2022, then slipped by 7.04% to -$371.4 million in 2023, then soared by 52.47% to -$176.5 million in 2024, then sank by 79.59% to -$317.0 million in 2025, then rose by 11.74% to -$279.8 million in 2026.
  • The last three Enterprise Value figures came in at -$279.8 million (Q1 2026), -$317.0 million (Q4 2025), and -$344.0 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Enterprise Value (Qtr)
1 Teva Pharmaceutical Industries 39.72 Bn 35.98 Bn 1.97 Bn -3.74 Bn
2 Zoetis 34.61 Bn 32.67 Bn 1.62 Bn -1.94 Bn
3 United Therapeutics 24.07 Bn 21.91 Bn 648.10 Mn -2.15 Bn
4 Aurora Cannabis 16.98 Bn 16.91 Bn 33.43 Mn -77.77 Mn
5 Neurocrine Biosciences 16.64 Bn 15.32 Bn 800.70 Mn -1.32 Bn
6 Elanco Animal Health 12.19 Bn 11.76 Bn 785.00 Mn -428.00 Mn
7 Alkermes 7.37 Bn 6.86 Bn -116.06 Mn -511.86 Mn
8 Hims & Hers Health 6.62 Bn 5.87 Bn 396.79 Mn -750.88 Mn
9 Lantheus Holdings 6.47 Bn 5.97 Bn 230.92 Mn -498.58 Mn
10 Amylyx Pharmaceuticals 1.51 Bn 1.51 Bn - -279.77 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -279.77 Mn
Dec 31, 2025 -316.98 Mn
Sep 30, 2025 -343.99 Mn
Jun 30, 2025 -180.83 Mn
Mar 31, 2025 -204.07 Mn
Dec 31, 2024 -176.50 Mn
Sep 30, 2024 -234.40 Mn
Jun 30, 2024 -309.81 Mn
Mar 31, 2024 -373.29 Mn
Dec 31, 2023 -371.36 Mn
Sep 30, 2023 -355.05 Mn
Jun 30, 2023 -357.28 Mn
Mar 31, 2023 -345.67 Mn
Dec 31, 2022 -346.95 Mn
Sep 30, 2022 -162.59 Mn
Jun 30, 2022 -206.68 Mn
Mar 31, 2022 -255.21 Mn
Dec 31, 2021 -96.12 Mn