Alnylam Pharmaceuticals (ALNY) Net Margin (2009 - 2026)
Alnylam Pharmaceuticals' Net Margin came in at 12.74% for Q2 2026, up 22.08 percentage points from -9.34% a year earlier but down 4.91 percentage points from the prior quarter.
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Analysis
Alnylam Pharmaceuticals (ALNY) Net Margin (2009 - 2026) Analysis & Trends
Over the trailing twelve months to Jun 30, 2026, Alnylam Pharmaceuticals reported Net Margin of 15.26%, up 30.32 percentage points year-over-year; for FY2025, it was 8.45%, up 20.82 percentage points from FY2024.
- Net Margin has increased in each of the last three years, with a five-year change of +182.59 percentage points (FY2020 to FY2025).
- Going back by year, Net Margin was -12.37% in FY2024 (+11.71 pp), -24.08% in FY2023 (+84.96 pp), -109.04% in FY2022 (-8.02 pp) and -101.01% in FY2021 (+73.13 pp).
- The five-year range for quarterly Net Margin is -153.58% (Q3 2022) to 20.10% (Q3 2025).
- Year-over-year, Net Margin has increased for four consecutive quarters, with an average year-over-year change of +11.03 percentage points over the last eight quarters.
- The fastest year-over-year change in Net Margin over five years came in Q3 2023 (a gain of 173.27 percentage points), and the weakest in Q1 2025 (a drop of 47.50 percentage points).
- Business Quant data shows ALNY's Net Margin at 17.65% (Q1 2026), 10.17% (Q4 2025) and 20.10% (Q3 2025) in the three quarters before Q2 2026.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 653.54 Bn | 572.07 Bn | 17.26 Bn | 21.86% |
| 2 | AbbVie | 467.01 Bn | 440.17 Bn | 12.70 Bn | 21.27% |
| 3 | Merck | 367.16 Bn | 321.59 Bn | 12.21 Bn | -8.04% |
| 4 | Novartis Ag | 277.56 Bn | 233.43 Bn | 11.24 Bn | 22.61% |
| 5 | Astrazeneca | 258.23 Bn | 231.79 Bn | 12.86 Bn | 18.81% |
| 6 | Amgen | 224.14 Bn | 179.54 Bn | 7.24 Bn | 23.62% |
| 7 | Gilead Sciences | 187.30 Bn | 161.42 Bn | 6.22 Bn | -134.51% |
| 8 | Pfizer | 163.47 Bn | 110.41 Bn | 10.94 Bn | -1.65% |
| 9 | Vertex Pharmaceuticals | 133.31 Bn | 105.31 Bn | 2.84 Bn | 32.99% |
| 10 | Alnylam Pharmaceuticals | 34.23 Bn | 22.28 Bn | 992.69 Mn | 12.74% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 12.74% |
| Mar 31, 2026 | 17.65% |
| Dec 31, 2025 | 10.17% |
| Sep 30, 2025 | 20.10% |
| Jun 30, 2025 | -9.34% |
| Dec 31, 2024 | -14.12% |
| Sep 30, 2024 | -22.27% |
| Jun 30, 2024 | -2.56% |
| Mar 31, 2024 | -13.34% |
| Dec 31, 2023 | -31.35% |
| Sep 30, 2023 | 19.69% |
| Jun 30, 2023 | -86.59% |
| Mar 31, 2023 | -54.53% |
| Dec 31, 2022 | -61.93% |
| Sep 30, 2022 | -153.58% |
| Jun 30, 2022 | -123.39% |
| Mar 31, 2022 | -112.70% |
| Dec 31, 2021 | -99.97% |
| Sep 30, 2021 | -109.00% |
| Jun 30, 2021 | -85.95% |
API Access
Alnylam Pharmaceuticals Net Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=net-margin&ticker=ALNY&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "net-margin", "ticker": "ALNY", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=net-margin&ticker=ALNY&period=max&api_key=YOUR_API_KEY");
const data = await res.json();