Alnylam Pharmaceuticals (ALNY) Free Cash Flow (2009 - 2026)

Alnylam Pharmaceuticals (ALNY) posted Free Cash Flow of $48.7 million for Q1 2026, down 57.48% on a QoQ basis from $114.5 million in Q4 2025, and up 137.65% year-over-year from $20.5 million in Q1 2025.

Alnylam Pharmaceuticals (ALNY) Free Cash Flow (2009 - 2026) Analysis & Trends

Alnylam Pharmaceuticals' Free Cash Flow history runs 18 years deep, the most recent figure standing at $48.7 million for Q1 2026.

  • Quarterly Free Cash Flow rose 137.65% year-over-year to $48.7 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $643.3 million (up 830.12% YoY) and the FY2025 annual result came in at $465.4 million, up 1192.73% from the prior year.
  • Free Cash Flow was $48.7 million for Q1 2026 at Alnylam Pharmaceuticals, down from $114.5 million in the prior quarter.
  • Across five years, Free Cash Flow topped out at $342.3 million in Q3 2023 and bottomed at -$197.9 million in Q4 2022.
  • A 5-year average of -$2.4 million and a median of -$74.9 million in 2023 frame the typical range for Free Cash Flow.
  • Annual changes were most pronounced in 2024 — Free Cash Flow slumped 880.0% — and 2025, when it surged 1629.56%.
  • Alnylam Pharmaceuticals' Free Cash Flow stood at -$197.9 million in 2022, then jumped by 106.72% to $13.3 million in 2023, then slumped by 880.0% to -$103.8 million in 2024, then jumped by 210.32% to $114.5 million in 2025, then sank by 57.48% to $48.7 million in 2026.
  • Business Quant data shows ALNY's Free Cash Flow at $48.7 million in Q1 2026, $114.5 million in Q4 2025, and $338.8 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Free Cash Flow (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -19.58 Mn
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -2.49 Mn
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 158.09 Mn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 1.29 Bn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 848.30 Mn
7 Belite Bio 61.40 Bn 61.40 Bn - -
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn -
9 Revolution Medicines 37.37 Bn 37.37 Bn - -354.95 Mn
10 Alnylam Pharmaceuticals 36.08 Bn 33.07 Bn 959.66 Mn 48.67 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 48.67 Mn
Mar 31, 2026 48.67 Mn
Dec 31, 2025 114.46 Mn
Dec 31, 2025 114.46 Mn
Sep 30, 2025 338.77 Mn
Sep 30, 2025 338.77 Mn
Jun 30, 2025 141.44 Mn
Jun 30, 2025 141.44 Mn
Mar 31, 2025 -129.28 Mn
Mar 31, 2025 -129.28 Mn
Dec 31, 2024 -103.76 Mn
Dec 31, 2024 -103.76 Mn
Sep 30, 2024 19.59 Mn
Sep 30, 2024 19.59 Mn
Jun 30, 2024 125.34 Mn
Jun 30, 2024 125.34 Mn
Mar 31, 2024 -83.76 Mn
Mar 31, 2024 -83.76 Mn
Dec 31, 2023 13.30 Mn
Dec 31, 2023 13.30 Mn