Alnylam Pharmaceuticals (ALNY) Free Cash Flow (2009 - 2026)
Alnylam Pharmaceuticals posted quarterly Free Cash Flow of $48.7 million for Q1 2026, up 137.65% year-on-year from $20.5 million in Q1 2025, and down 65.3% on a QoQ basis from $140.3 million in Q4 2025.
Alnylam Pharmaceuticals (ALNY) has 18 years of Free Cash Flow data on file, last reported at $48.7 million in Q1 2026.
- For the quarter ending Q1 2026, Free Cash Flow rose 137.65% year-over-year to $48.7 million; the trailing twelve-month figure through Mar 2026 stood at $643.3 million (up 830.12% YoY), and the FY2025 full-year result was $465.4 million, up 1192.73% from the prior year.
- Free Cash Flow for Q1 2026 stood at $48.7 million, down from $140.3 million in the prior quarter.
- Across five years, Free Cash Flow topped out at $342.3 million in Q3 2023 and bottomed at -$180.4 million in Q1 2023.
- The 5-year median for Free Cash Flow is -$74.9 million (2023), against an average of -$1.9 million.
- The widest annual swing landed in 2024, when Free Cash Flow plunged 130.04%; it then jumped 1399.9% in 2025.
- A 5-year view of Free Cash Flow shows it stood at -$86.8 million in 2022, then surged by 48.02% to -$45.1 million in 2023, then slumped by 130.04% to -$103.8 million in 2024, then jumped by 235.19% to $140.3 million in 2025, then sank by 65.3% to $48.7 million in 2026.
- The last three Free Cash Flow figures came in at $48.7 million (Q1 2026), $140.3 million (Q4 2025), and $293.8 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Free Cash Flow (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 961,148.99 Bn | 961,148.98 Bn | - | -1.67 Mn |
| 2 | Alterity Therapeutics | 744,933.29 Bn | 744,933.26 Bn | - | - |
| 3 | Legend Biotech | 2,540.00 Bn | 2,539.71 Bn | 242.10 Mn | -12.20 Mn |
| 4 | Nanobiotix | 2,199.85 Bn | 2,199.78 Bn | - | - |
| 5 | Akari Therapeutics | 1,635.88 Bn | 1,635.88 Bn | - | -2.49 Mn |
| 6 | Vertex Pharmaceuticals | 111.32 Bn | 104.07 Bn | 2.59 Bn | 1.29 Bn |
| 7 | Evaxion A | 62.56 Bn | 62.54 Bn | - | - |
| 8 | Regeneron Pharmaceuticals | 62.55 Bn | 53.79 Bn | 3.31 Bn | 848.30 Mn |
| 9 | Alnylam Pharmaceuticals | 39.57 Bn | 36.56 Bn | 959.66 Mn | 48.67 Mn |
| 10 | Revolution Medicines | 32.39 Bn | 32.39 Bn | - | -354.95 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 48.67 Mn |
| Mar 31, 2026 | 48.67 Mn |
| Dec 31, 2025 | 140.26 Mn |
| Dec 31, 2025 | 140.26 Mn |
| Sep 30, 2025 | 293.79 Mn |
| Sep 30, 2025 | 293.79 Mn |
| Jun 30, 2025 | 160.62 Mn |
| Jun 30, 2025 | 160.62 Mn |
| Mar 31, 2025 | -129.28 Mn |
| Mar 31, 2025 | -129.28 Mn |
| Dec 31, 2024 | -103.76 Mn |
| Dec 31, 2024 | -103.76 Mn |
| Sep 30, 2024 | 19.59 Mn |
| Sep 30, 2024 | 19.59 Mn |
| Jun 30, 2024 | 125.34 Mn |
| Jun 30, 2024 | 125.34 Mn |
| Mar 31, 2024 | -83.76 Mn |
| Mar 31, 2024 | -83.76 Mn |
| Dec 31, 2023 | -45.10 Mn |
| Dec 31, 2023 | -45.10 Mn |
| Sep 30, 2023 | 342.32 Mn |
| Sep 30, 2023 | 342.32 Mn |
| Jun 30, 2023 | -74.91 Mn |
| Jun 30, 2023 | -74.91 Mn |
| Mar 31, 2023 | -180.37 Mn |
| Mar 31, 2023 | -180.37 Mn |
| Dec 31, 2022 | -86.77 Mn |
| Dec 31, 2022 | -86.77 Mn |
| Sep 30, 2022 | -131.79 Mn |
| Sep 30, 2022 | -131.79 Mn |
| Jun 30, 2022 | -148.42 Mn |
| Jun 30, 2022 | -148.42 Mn |
| Mar 31, 2022 | -179.51 Mn |
| Mar 31, 2022 | -179.51 Mn |
| Dec 31, 2021 | -109.25 Mn |
| Dec 31, 2021 | -109.25 Mn |
| Sep 30, 2021 | -160.10 Mn |
| Sep 30, 2021 | -160.10 Mn |
| Jun 30, 2021 | -142.99 Mn |
| Jun 30, 2021 | -142.99 Mn |
| Mar 31, 2021 | -242.95 Mn |
| Mar 31, 2021 | -242.95 Mn |
| Dec 31, 2020 | -144.81 Mn |
| Dec 31, 2020 | -144.81 Mn |
| Sep 30, 2020 | -122.74 Mn |
| Sep 30, 2020 | -122.74 Mn |
| Jun 30, 2020 | -151.99 Mn |
| Jun 30, 2020 | -151.99 Mn |
| Mar 31, 2020 | -265.78 Mn |
| Mar 31, 2020 | -265.78 Mn |
| Dec 31, 2019 | -109.51 Mn |
| Dec 31, 2019 | -109.51 Mn |
| Sep 30, 2019 | -218.69 Mn |
| Sep 30, 2019 | -218.69 Mn |
| Jun 30, 2019 | 236.44 Mn |
| Jun 30, 2019 | 236.44 Mn |
| Mar 31, 2019 | -201.54 Mn |
| Mar 31, 2019 | -201.54 Mn |
| Dec 31, 2018 | -257.61 Mn |
| Dec 31, 2018 | -257.61 Mn |
| Sep 30, 2018 | -129.58 Mn |
| Sep 30, 2018 | -129.58 Mn |
| Jun 30, 2018 | -125.40 Mn |
| Jun 30, 2018 | -125.40 Mn |
| Mar 31, 2018 | -176.92 Mn |
| Mar 31, 2018 | -176.92 Mn |
| Dec 31, 2017 | -123.77 Mn |
| Dec 31, 2017 | -123.77 Mn |
| Sep 30, 2017 | -124.04 Mn |
| Sep 30, 2017 | -124.04 Mn |
| Jun 30, 2017 | -102.70 Mn |
| Jun 30, 2017 | -102.70 Mn |
| Mar 31, 2017 | -136.48 Mn |
| Mar 31, 2017 | -136.48 Mn |
| Dec 31, 2016 | -66.81 Mn |
| Dec 31, 2016 | -66.81 Mn |
| Sep 30, 2016 | -95.83 Mn |
| Sep 30, 2016 | -95.83 Mn |
| Jun 30, 2016 | -85.53 Mn |
| Jun 30, 2016 | -85.53 Mn |
| Mar 31, 2016 | -92.68 Mn |
| Mar 31, 2016 | -92.68 Mn |
| Dec 31, 2015 | -56.16 Mn |
| Dec 31, 2015 | -56.16 Mn |
| Sep 30, 2015 | -60.84 Mn |
| Sep 30, 2015 | -60.84 Mn |
| Jun 30, 2015 | -56.72 Mn |
| Jun 30, 2015 | -56.72 Mn |
| Mar 31, 2015 | -28.37 Mn |
| Mar 31, 2015 | -28.37 Mn |
| Dec 31, 2014 | -40.16 Mn |
| Dec 31, 2014 | -40.16 Mn |
| Sep 30, 2014 | -43.90 Mn |
| Sep 30, 2014 | -43.90 Mn |
| Jun 30, 2014 | -48.48 Mn |
| Jun 30, 2014 | -48.48 Mn |
| Mar 31, 2014 | -42.06 Mn |
| Mar 31, 2014 | -42.06 Mn |
| Dec 31, 2013 | -19.40 Mn |
| Dec 31, 2013 | -19.40 Mn |
| Sep 30, 2013 | -22.67 Mn |
| Sep 30, 2013 | -22.67 Mn |
| Jun 30, 2013 | -23.98 Mn |
| Jun 30, 2013 | -23.98 Mn |
| Mar 31, 2013 | -2.77 Mn |
| Mar 31, 2013 | -2.77 Mn |
| Dec 31, 2012 | -62.69 Mn |
| Dec 31, 2012 | -62.69 Mn |
| Sep 30, 2012 | -517,000.00 |
| Sep 30, 2012 | -517,000.00 |
| Jun 30, 2012 | -23.36 Mn |
| Jun 30, 2012 | -23.36 Mn |
| Mar 31, 2012 | -30.48 Mn |
| Mar 31, 2012 | -30.48 Mn |
| Dec 31, 2011 | -25.68 Mn |
| Dec 31, 2011 | -25.68 Mn |
| Sep 30, 2011 | -29.29 Mn |
| Sep 30, 2011 | -29.29 Mn |
| Jun 30, 2011 | -27.05 Mn |
| Jun 30, 2011 | -27.05 Mn |
| Mar 31, 2011 | -6.33 Mn |
| Mar 31, 2011 | -6.33 Mn |
| Dec 31, 2010 | -21.53 Mn |
| Dec 31, 2010 | -21.53 Mn |
| Sep 30, 2010 | -25.11 Mn |
| Sep 30, 2010 | -25.11 Mn |
| Jun 30, 2010 | -25.74 Mn |
| Jun 30, 2010 | -25.74 Mn |
| Mar 31, 2010 | -16.70 Mn |
| Mar 31, 2010 | -16.70 Mn |
| Dec 31, 2009 | -18.13 Mn |
| Dec 31, 2009 | -18.13 Mn |
| Sep 30, 2009 | -21.33 Mn |
| Sep 30, 2009 | -21.33 Mn |