Alnylam Pharmaceuticals (ALNY) FCF Margin (2009 - 2026)

Alnylam Pharmaceuticals (ALNY) posted FCF Margin of 4.17% for Q1 2026, down 60.03% on a QoQ basis from 10.43% in Q4 2025, and up 2593.0% year-over-year from 0.15% in Q1 2025.

Alnylam Pharmaceuticals (ALNY) FCF Margin (2009 - 2026) Analysis & Trends

Alnylam Pharmaceuticals' FCF Margin history runs 18 years deep, the most recent figure standing at 4.17% for Q1 2026.

  • Quarterly FCF Margin rose 2593.0% year-over-year to 4.17% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 15.01% (up 1876.0% YoY) and the FY2025 annual result came in at 12.53%, up 1443.0% from the prior year.
  • FCF Margin was 4.17% for Q1 2026 at Alnylam Pharmaceuticals, down from 10.43% in the prior quarter.
  • Across five years, FCF Margin topped out at 45.61% in Q3 2023 and bottomed at 88.65% in Q1 2022.
  • A 5-year average of 14.54% and a median of 16.94% in 2024 frame the typical range for FCF Margin.
  • Annual changes were most pronounced in 2023 — FCF Margin soared 7873 bps — and 2024, when it slumped 4170 bps.
  • Alnylam Pharmaceuticals' FCF Margin stood at 59.06% in 2022, then surged by 105 bps to 3.03% in 2023, then tumbled by 678 bps to 17.49% in 2024, then jumped by 160 bps to 10.43% in 2025, then sank by 60 bps to 4.17% in 2026.
  • Business Quant data shows ALNY's FCF Margin at 4.17% in Q1 2026, 10.43% in Q4 2025, and 27.12% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) FCF Margin (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 10.45%
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 43.35%
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 23.53%
7 Belite Bio 61.40 Bn 61.40 Bn - -
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn -
9 Revolution Medicines 37.37 Bn 37.37 Bn - -
10 Alnylam Pharmaceuticals 36.08 Bn 33.07 Bn 959.66 Mn 4.17%

Historic Data

Download Data
DateValue
Mar 31, 2026 4.17%
Dec 31, 2025 10.43%
Sep 30, 2025 27.12%
Jun 30, 2025 18.28%
Mar 31, 2025 -21.76%
Dec 31, 2024 -17.49%
Sep 30, 2024 3.91%
Jun 30, 2024 19.00%
Mar 31, 2024 -16.94%
Dec 31, 2023 3.03%
Sep 30, 2023 45.61%
Jun 30, 2023 -23.50%
Mar 31, 2023 -56.49%
Dec 31, 2022 -59.06%
Sep 30, 2022 -33.12%
Jun 30, 2022 -61.77%
Mar 31, 2022 -88.65%
Dec 31, 2021 -42.26%
Sep 30, 2021 -85.33%
Jun 30, 2021 -64.83%