Alnylam Pharmaceuticals (ALNY) EBITDA Margin (2009 - 2026)
Alnylam Pharmaceuticals' EBITDA Margin was 19.00% in Q2 2026, up 19.30 percentage points from -0.29% a year earlier but down 5.17 percentage points from the prior quarter.
Alnylam Pharmaceuticals (ALNY) EBITDA Margin (2009 - 2026) Analysis & Trends
On a trailing twelve-month basis, Alnylam Pharmaceuticals' EBITDA Margin was 21.95% through Jun 30, 2026, up 28.47 percentage points year-over-year; for FY2025, it was 15.00%, up 20.35 percentage points from FY2024.
- EBITDA Margin has now increased for seven consecutive years, with a five-year change of +176.04 percentage points (FY2020 to FY2025).
- In earlier years, EBITDA Margin was -5.35% in FY2024 (+7.13 pp), -12.48% in FY2023 (+58.91 pp), -71.39% in FY2022 (+6.91 pp) and -78.30% in FY2021 (+82.73 pp).
- Quarterly EBITDA Margin has moved between -93.62% (Q3 2022) and 108.27% (Q1 2025) over five years.
- Compared with a year earlier, EBITDA Margin was higher in five of the last eight quarters, with an average year-over-year change of +9.57 percentage points.
- The best year-over-year quarter for EBITDA Margin over five years was Q3 2023 (a gain of 123.89 percentage points); the worst was Q1 2026 (a drop of 84.10 percentage points).
- Per Business Quant data, ALNY's EBITDA Margin in the three quarters before Q2 2026 was 24.18% (Q1 2026), 13.24% (Q4 2025) and 30.57% (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 653.54 Bn | 572.07 Bn | 17.26 Bn | 35.95% |
| 2 | AbbVie | 467.01 Bn | 440.17 Bn | 12.70 Bn | 49.01% |
| 3 | Merck | 367.16 Bn | 321.59 Bn | 12.21 Bn | 6.02% |
| 4 | Novartis Ag | 277.56 Bn | 233.43 Bn | 11.24 Bn | - |
| 5 | Astrazeneca | 258.23 Bn | 231.79 Bn | 12.86 Bn | 33.11% |
| 6 | Amgen | 224.14 Bn | 179.54 Bn | 7.24 Bn | 46.01% |
| 7 | Gilead Sciences | 187.30 Bn | 161.42 Bn | 6.22 Bn | -124.26% |
| 8 | Pfizer | 163.47 Bn | 110.41 Bn | 10.94 Bn | 39.16% |
| 9 | Vertex Pharmaceuticals | 133.31 Bn | 105.31 Bn | 2.84 Bn | 39.10% |
| 10 | Alnylam Pharmaceuticals | 34.23 Bn | 22.28 Bn | 992.69 Mn | 19.00% |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 19.00% |
| Mar 31, 2026 | 24.18% |
| Dec 31, 2025 | 13.24% |
| Sep 30, 2025 | 30.57% |
| Jun 30, 2025 | -0.29% |
| Dec 31, 2024 | -15.34% |
| Sep 30, 2024 | -12.56% |
| Jun 30, 2024 | 9.64% |
| Mar 31, 2024 | -6.05% |
| Dec 31, 2023 | -23.41% |
| Sep 30, 2023 | 30.27% |
| Jun 30, 2023 | -67.97% |
| Mar 31, 2023 | -42.51% |
| Dec 31, 2022 | -52.03% |
| Sep 30, 2022 | -93.62% |
| Jun 30, 2022 | -80.77% |
| Mar 31, 2022 | -64.37% |
| Dec 31, 2021 | -70.86% |
| Sep 30, 2021 | -90.54% |
| Jun 30, 2021 | -60.92% |
Alnylam Pharmaceuticals EBITDA Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=ebitda-margin&ticker=ALNY&period=max&api_key=YOUR_API_KEY
import requests
url = "https://data.businessquant.com/historic"
params = {"slug": "ebitda-margin", "ticker": "ALNY", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()
const res = await fetch("https://data.businessquant.com/historic?slug=ebitda-margin&ticker=ALNY&period=max&api_key=YOUR_API_KEY");
const data = await res.json();