Growth Metrics

Alnylam Pharmaceuticals (ALNY) EBIT Margin (2009 - 2026)

Alnylam Pharmaceuticals posted quarterly EBIT Margin of 23.02% for Q1 2026, down 3724.0% year-on-year from 0.64% in Q1 2025, and up 91.69% on a QoQ basis from 12.01% in Q4 2025.

Alnylam Pharmaceuticals (ALNY) has 18 years of EBIT Margin data on file, last reported at 23.02% in Q1 2026.

  • For the quarter ending Q1 2026, EBIT Margin fell 3724.0% year-over-year to 23.02%; the trailing twelve-month figure through Mar 2026 stood at 17.54% (up 2401.0% YoY), and the FY2025 full-year result was 13.51%, up 2137.0% from the prior year.
  • EBIT Margin for Q1 2026 stood at 23.02%, up from 12.01% in the prior quarter.
  • Across five years, EBIT Margin topped out at 60.26% in Q1 2025 and bottomed at 97.63% in Q3 2022.
  • The 5-year median for EBIT Margin is 15.35% (2024), against an average of 19.81%.
  • The widest annual swing landed in 2023, when EBIT Margin jumped 12612 bps; it then tumbled 4385 bps in 2024.
  • A 5-year view of EBIT Margin shows it stood at 56.3% in 2022, then soared by 53 bps to 26.47% in 2023, then soared by 33 bps to 17.73% in 2024, then jumped by 168 bps to 12.01% in 2025, then jumped by 92 bps to 23.02% in 2026.
  • The last three EBIT Margin figures came in at 23.02% (Q1 2026), 12.01% (Q4 2025), and 29.46% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBIT Margin (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -6.43%
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 38.10%
7 Evaxion A 62.56 Bn 62.54 Bn - -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 17.83%
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 23.02%
10 Revolution Medicines 32.39 Bn 32.39 Bn - -

Historic Data

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DateValue
Mar 31, 2026 23.02%
Dec 31, 2025 12.01%
Sep 30, 2025 29.46%
Jun 30, 2025 -2.09%
Mar 31, 2025 60.26%
Dec 31, 2024 -17.73%
Sep 30, 2024 -15.35%
Jun 30, 2024 7.37%
Mar 31, 2024 -8.79%
Dec 31, 2023 -26.47%
Sep 30, 2023 28.50%
Jun 30, 2023 -72.10%
Mar 31, 2023 -46.92%
Dec 31, 2022 -56.30%
Sep 30, 2022 -97.63%
Jun 30, 2022 -85.26%
Mar 31, 2022 -68.80%
Dec 31, 2021 -75.26%
Sep 30, 2021 -96.83%
Jun 30, 2021 -66.27%
Mar 31, 2021 -104.89%
Dec 31, 2020 -118.75%
Sep 30, 2020 -178.94%
Jun 30, 2020 -191.28%
Mar 31, 2020 -211.27%
Dec 31, 2019 -415.83%
Sep 30, 2019 -308.73%
Jun 30, 2019 -528.40%
Mar 31, 2019 -567.03%
Dec 31, 2018 -1,047.67%
Sep 30, 2018 -12,303.43%
Jun 30, 2018 -643.17%
Mar 31, 2018 -673.11%
Dec 31, 2017 -388.42%
Sep 30, 2017 -735.84%
Jun 30, 2017 -756.18%
Mar 31, 2017 -561.77%
Dec 31, 2016 -661.36%
Sep 30, 2016 -781.45%
Jun 30, 2016 -1,061.55%
Mar 31, 2016 -1,498.00%
Dec 31, 2015 -1,225.16%
Sep 30, 2015 -1,238.61%
Jun 30, 2015 -839.88%
Mar 31, 2015 -281.72%
Dec 31, 2014 -190.32%
Sep 30, 2014 -411.95%
Jun 30, 2014 -616.93%
Mar 31, 2014 -3,251.53%
Dec 31, 2013 -272.81%
Sep 30, 2013 -358.51%
Jun 30, 2013 -245.33%
Mar 31, 2013 -52.59%
Dec 31, 2012 -1,040.01%
Sep 30, 2012 -108.28%
Jun 30, 2012 -57.78%
Mar 31, 2012 -52.91%
Dec 31, 2011 -66.42%
Sep 30, 2011 -59.82%
Jun 30, 2011 -63.64%
Mar 31, 2011 -75.02%
Dec 31, 2010 -58.56%
Sep 30, 2010 -31.55%
Jun 30, 2010 -43.68%
Mar 31, 2010 -46.03%
Dec 31, 2009 -30.30%
Sep 30, 2009 -39.80%
Jun 30, 2009 -91.10%