Alnylam Pharmaceuticals (ALNY) Cost of Revenue (2018 - 2026)

Alnylam Pharmaceuticals (ALNY) posted Cost of Revenue of $207.5 million for Q1 2026, down 22.49% on a QoQ basis from $267.7 million in Q4 2025, and up 195.68% year-over-year from $70.2 million in Q1 2025.

Alnylam Pharmaceuticals (ALNY) Cost of Revenue (2018 - 2026) Analysis & Trends

Alnylam Pharmaceuticals' Cost of Revenue history runs 9 years deep, the most recent figure standing at $207.5 million for Q1 2026.

  • Quarterly Cost of Revenue rose 195.68% year-over-year to $207.5 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $814.5 million (up 152.89% YoY) and the FY2025 annual result came in at $677.2 million, up 120.93% from the prior year.
  • Cost of Revenue was $207.5 million for Q1 2026 at Alnylam Pharmaceuticals, down from $267.7 million in the prior quarter.
  • Across five years, Cost of Revenue topped out at $267.7 million in Q4 2025 and bottomed at $23.5 million in Q1 2022.
  • A 5-year average of $94.1 million and a median of $72.0 million in 2023 frame the typical range for Cost of Revenue.
  • Annual changes were most pronounced in 2024 — Cost of Revenue fell 10.71% — and 2026, when it soared 195.68%.
  • Alnylam Pharmaceuticals' Cost of Revenue stood at $46.2 million in 2022, then jumped by 55.88% to $72.0 million in 2023, then surged by 42.62% to $102.6 million in 2024, then soared by 160.81% to $267.7 million in 2025, then declined by 22.49% to $207.5 million in 2026.
  • Business Quant data shows ALNY's Cost of Revenue at $207.5 million in Q1 2026, $267.7 million in Q4 2025, and $197.2 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Cost of Rev (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 167.22 Mn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 392.80 Mn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 296.00 Mn
7 Belite Bio 61.40 Bn 61.40 Bn - -
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn 121.00 Mn
9 Revolution Medicines 37.37 Bn 37.37 Bn - -
10 Alnylam Pharmaceuticals 36.08 Bn 33.07 Bn 959.66 Mn 207.52 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 207.52 Mn
Mar 31, 2026 207.52 Mn
Dec 31, 2025 267.72 Mn
Dec 31, 2025 267.72 Mn
Sep 30, 2025 197.23 Mn
Sep 30, 2025 197.23 Mn
Jun 30, 2025 142.03 Mn
Jun 30, 2025 142.03 Mn
Mar 31, 2025 70.18 Mn
Mar 31, 2025 70.18 Mn
Dec 31, 2024 102.65 Mn
Dec 31, 2024 102.65 Mn
Sep 30, 2024 81.98 Mn
Sep 30, 2024 81.98 Mn
Jun 30, 2024 67.27 Mn
Jun 30, 2024 67.27 Mn
Mar 31, 2024 54.61 Mn
Mar 31, 2024 54.61 Mn
Dec 31, 2023 71.98 Mn
Dec 31, 2023 71.98 Mn