Alumis (ALMS) Profit After Tax (2023 - 2026)

Alumis (ALMS) posted quarterly Profit After Tax of -$324.9 million for Q4 2025, down 242.84% year-over-year from $227.4 million in Q4 2024, and down 193.33% quarter-over-quarter from -$110.8 million in Q3 2025.

Alumis (ALMS) Profit After Tax (2023 - 2026) Analysis & Trends

Alumis (ALMS) has reported Profit After Tax for 3 consecutive years, with -$324.9 million the latest figure, recorded in Q4 2025.

  • In Q4 2025, Profit After Tax fell 242.84% year-over-year to -$324.9 million; the TTM figure through Dec 2025 stood at -$475.3 million (down 38.65% YoY), while the FY2025 annual figure was -$475.1 million, down 61.46% from the prior year.
  • Profit After Tax slipped to -$324.9 million in Q4 2025 per ALMS's latest filing, from -$110.8 million in the prior quarter.
  • Across five years, Profit After Tax topped out at $59.3 million in Q2 2025 and bottomed at -$324.9 million in Q4 2025.
  • Historically, Profit After Tax has averaged -$85.2 million across 3 years, with a median of -$56.5 million in 2024.
  • On a YoY basis, Profit After Tax climbed as much as 204.98% in 2025 and fell as far as 242.84% in 2025.
  • Alumis' Profit After Tax stood at -$39.3 million in 2023, then sank by 141.07% to -$94.8 million in 2024, then plunged by 242.84% to -$324.9 million in 2025.
  • Business Quant data shows ALMS's Profit After Tax at -$324.9 million in Q4 2025, -$110.8 million in Q3 2025, and $59.3 million in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) PAT (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 1.10 Bn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 1.30 Bn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 472.00 Mn
4 Revolution Medicines 43.64 Bn 43.64 Bn - -644.37 Mn
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 237.01 Mn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -3,087.27
7 Royalty Pharma 33.72 Bn 35.84 Bn - 81.49 Mn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 164.49 Mn
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -16.62 Mn
10 Alumis 3.25 Bn 2.75 Bn - -142.44 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 -142.44 Mn
Dec 31, 2025 -324.87 Mn
Sep 30, 2025 -110.75 Mn
Jun 30, 2025 59.32 Mn
Mar 31, 2025 -98.96 Mn
Dec 31, 2024 -94.76 Mn
Sep 30, 2024 -141.67 Mn
Jun 30, 2024 -56.51 Mn
Mar 31, 2024 -49.85 Mn
Dec 31, 2023 -39.31 Mn
Sep 30, 2023 -43.38 Mn
Jun 30, 2023 -36.29 Mn