Alumis (ALMS) Net Cash Flow (2023 - 2025)

Alumis (ALMS) reported Net Cash Flow of $24.4 million for Q4 2025, up 155.75% year-over-year from $9.5 million in Q4 2024, and up 128.11% on a QoQ basis from -$86.9 million in Q3 2025.

Alumis (ALMS) has 3 years of Net Cash Flow data on file, last reported at $24.4 million in Q4 2025.

  • Quarterly Net Cash Flow rose 155.75% year-over-year to $24.4 million in Q4 2025, while the trailing twelve-month figure through Dec 2025 was -$80.3 million (down 165.04% YoY) and the FY2025 annual result came in at -$79.6 million, down 164.44% from the prior year.
  • Net Cash Flow improved to $24.4 million in Q4 2025 per ALMS's latest filing, from -$86.9 million in the prior quarter.
  • Across five years, Net Cash Flow topped out at $66.0 million in Q1 2024 and bottomed at -$86.9 million in Q3 2025.
  • The 3-year median for Net Cash Flow is $7.4 million (2023), against an average of $939900.0.
  • Peak annual rise in Net Cash Flow reached 327.34% in 2024, while the deepest fall reached 434.58% in 2024.
  • Tracing ALMS's Net Cash Flow over 3 years: stood at -$8.2 million in 2023, then plunged by 434.58% to -$43.8 million in 2024, then jumped by 155.75% to $24.4 million in 2025.
  • Per Business Quant, the three latest ALMS Net Cash Flow figures stand at $24.4 million (Q4 2025), -$86.9 million (Q3 2025), and $23.1 million (Q2 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Cash Flow (Qtr)
1 Quantum Biopharma 1,216,509.61 Bn 1,216,509.61 Bn - 2.44 Mn
2 Alterity Therapeutics 764,224.41 Bn 764,224.38 Bn - -
3 Legend Biotech 2,716.00 Bn 2,715.71 Bn 242.10 Mn 625.70 Mn
4 Nanobiotix 2,248.83 Bn 2,248.77 Bn - -
5 Akari Therapeutics 1,951.18 Bn 1,951.17 Bn - -2.44 Mn
6 Vertex Pharmaceuticals 113.69 Bn 106.44 Bn 2.59 Bn 457.40 Mn
7 Evaxion A 64.16 Bn 64.14 Bn - -
8 Regeneron Pharmaceuticals 63.94 Bn 55.18 Bn 3.31 Bn -152.20 Mn
9 Alnylam Pharmaceuticals 40.13 Bn 37.12 Bn 959.66 Mn 60.68 Mn
10 Alumis 1.84 Bn 1.75 Bn - 24.42 Mn

Historic Data

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DateValue
Dec 31, 2025 24.42 Mn
Dec 31, 2025 24.42 Mn
Sep 30, 2025 -86.88 Mn
Sep 30, 2025 -86.88 Mn
Jun 30, 2025 23.06 Mn
Jun 30, 2025 23.06 Mn
Mar 31, 2025 -40.93 Mn
Mar 31, 2025 -40.93 Mn
Dec 31, 2024 -43.81 Mn
Dec 31, 2024 -43.81 Mn
Sep 30, 2024 58.15 Mn
Sep 30, 2024 58.15 Mn
Jun 30, 2024 43.12 Mn
Jun 30, 2024 43.12 Mn
Mar 31, 2024 66.04 Mn
Mar 31, 2024 66.04 Mn
Dec 31, 2023 -8.20 Mn
Dec 31, 2023 -8.20 Mn
Sep 30, 2023 -25.58 Mn
Sep 30, 2023 -25.58 Mn