Alumis (ALMS) Free Cash Flow (2023 - 2025)

Alumis (ALMS) posted quarterly Free Cash Flow of -$76.8 million for Q4 2025, down 2.18% year-over-year from -$78.5 million in Q4 2024, and up 30.79% quarter-over-quarter from -$110.9 million in Q3 2025.

Alumis (ALMS) Free Cash Flow (2023 - 2025) Analysis & Trends

Alumis (ALMS) has reported Free Cash Flow for 3 consecutive years, with -$76.8 million the latest figure, recorded in Q4 2025.

  • In Q4 2025, Free Cash Flow fell 2.18% year-over-year to -$76.8 million; the TTM figure through Dec 2025 stood at -$375.0 million (down 46.04% YoY), while the FY2025 annual figure was -$375.0 million, down 46.04% from the prior year.
  • Free Cash Flow grew to -$76.8 million in Q4 2025 per ALMS's latest filing, from -$110.9 million in the prior quarter.
  • Across five years, Free Cash Flow topped out at -$35.0 million in Q4 2023 and bottomed at -$110.9 million in Q3 2025.
  • Historically, Free Cash Flow has averaged -$70.2 million across 3 years, with a median of -$75.9 million in 2024.
  • Annual changes were most pronounced in 2024 — Free Cash Flow plunged 139.05% — and 2025, when it decreased 2.18%.
  • Alumis' Free Cash Flow stood at -$35.0 million in 2023, then plunged by 114.6% to -$75.1 million in 2024, then retreated by 2.18% to -$76.8 million in 2025.
  • Business Quant data shows ALMS's Free Cash Flow at -$76.8 million in Q4 2025, -$110.9 million in Q3 2025, and -$106.9 million in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Free Cash Flow (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 1.01 Bn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 572.80 Mn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn -
4 Revolution Medicines 43.64 Bn 43.64 Bn - -389.61 Mn
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 437.80 Mn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -2.33 Mn
7 Royalty Pharma 33.72 Bn 35.84 Bn - 477.44 Mn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 292.04 Mn
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -95.09 Mn
10 Alumis 3.25 Bn 2.75 Bn - -

Historic Data

Download Data
DateValue
Dec 31, 2025 -76.77 Mn
Dec 31, 2025 -76.77 Mn
Sep 30, 2025 -110.92 Mn
Sep 30, 2025 -110.92 Mn
Jun 30, 2025 -106.92 Mn
Jun 30, 2025 -106.92 Mn
Mar 31, 2025 -80.44 Mn
Mar 31, 2025 -80.44 Mn
Dec 31, 2024 -75.13 Mn
Dec 31, 2024 -75.13 Mn
Sep 30, 2024 -84.55 Mn
Sep 30, 2024 -84.55 Mn
Jun 30, 2024 -52.68 Mn
Jun 30, 2024 -52.68 Mn
Mar 31, 2024 -44.46 Mn
Mar 31, 2024 -44.46 Mn
Dec 31, 2023 -35.01 Mn
Dec 31, 2023 -35.01 Mn
Sep 30, 2023 -35.37 Mn
Sep 30, 2023 -35.37 Mn