Alumis (ALMS) Change in Cash (2023 - 2025)

Alumis (ALMS) posted quarterly Change in Cash of $24.4 million for Q4 2025, up 155.75% year-over-year from $9.5 million in Q4 2024, and up 128.11% quarter-over-quarter from -$86.9 million in Q3 2025.

Alumis (ALMS) Change in Cash (2023 - 2025) Analysis & Trends

Alumis (ALMS) has reported Change in Cash for 3 consecutive years, with $24.4 million the latest figure, recorded in Q4 2025.

  • In Q4 2025, Change in Cash rose 155.75% year-over-year to $24.4 million; the TTM figure through Dec 2025 stood at -$79.6 million (down 164.44% YoY), while the FY2025 annual figure was -$79.6 million, down 164.44% from the prior year.
  • Change in Cash grew to $24.4 million in Q4 2025 per ALMS's latest filing, from -$86.9 million in the prior quarter.
  • Across five years, Change in Cash topped out at $66.1 million in Q1 2024 and bottomed at -$86.9 million in Q3 2025.
  • Historically, Change in Cash has averaged $1.0 million across 3 years, with a median of $7.8 million in 2023.
  • On a YoY basis, Change in Cash climbed as much as 327.12% in 2024 and fell as far as 437.73% in 2024.
  • Alumis' Change in Cash stood at -$8.1 million in 2023, then plunged by 437.73% to -$43.8 million in 2024, then jumped by 155.75% to $24.4 million in 2025.
  • Business Quant data shows ALMS's Change in Cash at $24.4 million in Q4 2025, -$86.9 million in Q3 2025, and $23.8 million in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Change in Cash (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 649.20 Mn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn -504.60 Mn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn -
4 Revolution Medicines 43.64 Bn 43.64 Bn - 374.50 Mn
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 427.25 Mn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -1.97 Mn
7 Royalty Pharma 33.72 Bn 35.84 Bn - 225.59 Mn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn -2.94 Mn
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -37.42 Mn
10 Alumis 3.25 Bn 2.75 Bn - -

Historic Data

Download Data
DateValue
Dec 31, 2025 24.42 Mn
Sep 30, 2025 -86.87 Mn
Jun 30, 2025 23.80 Mn
Mar 31, 2025 -40.93 Mn
Dec 31, 2024 -43.81 Mn
Sep 30, 2024 58.20 Mn
Jun 30, 2024 43.04 Mn
Mar 31, 2024 66.08 Mn
Dec 31, 2023 -8.15 Mn
Sep 30, 2023 -25.62 Mn