VCEL vs TSHA vs LEGN Stock Comparison

Vericel, Taysha Gene Therapies and Legend Biotech Prices as of Nov 3, 2026 Peers: Industry group
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VCEL Vericel Corp
$41.09 +2.3% 1M +11.9% 1Y
Market cap
$2.32B
P/E
95.9x
Revenue (TTM)
$306.30M
Div. yield
–
Gene and Cell Therapy Healthcare
5 wins
LEGN Legend Biotech Corp
$21.48 +15.7% 1M -33.1% 1Y
Market cap
$4.23B
P/E
–
Revenue (TTM)
$1.27B
Div. yield
–
Gene and Cell Therapy Healthcare
3 wins

Head to Head

8 decided of 12

Vericel leads on 5 of the 12 questions below (Vericel 5, Legend Biotech 3). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionVCELTSHALEGNLeader
Larger companyMarket capitalisation $2.32B $1.61B $4.23B LEGN
Cheaper on earningsLower P/E, profitable companies only 95.9x -10.7x -46.2x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS 80.6x — — –
Faster revenue growthRevenue growth, trailing twelve months +23.0% -32.3% +59.5% LEGN
More profitableNet margin, trailing twelve months 7.9% -2,728.0% -7.2% VCEL
Better return on capitalReturn on invested capital — — -4.2% –
Less leveragedLower net debt / EBITDA — 2.7x -130.2x LEGN
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +11.9% -8.3% -33.1% VCEL
Better 5-year returnAnnualised price return, 5 years -3.3%/yr -24.1%/yr -15.1%/yr VCEL
Less volatileAnnualised volatility, 1 year 41.3% 70.8% 72.4% VCEL
Higher overall scoreMean of the five percentile scores vs peers 81/100 48/100 74/100 VCEL

Percentile Scorecard

VCELTSHALEGN

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisVCELTSHALEGN
Valuation 82 #113 of 634 46 #340 of 634 88 #75 of 634
Growth 94 #37 of 607 16 #508 of 607 97 #20 of 607
Profitability 89 #65 of 557 26 #410 of 557 80 #112 of 557
Financial Health 68 #208 of 654 76 #161 of 654 60 #262 of 654
Shareholder Returns 72 #115 of 401 78 #91 of 401 44 #227 of 401
Overall 81 48 74
  • VCEL ranked among 671 companies in Pharmaceuticals and Biotechnology
  • TSHA ranked among 671 companies in Pharmaceuticals and Biotechnology
  • LEGN ranked among 671 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodVCELTSHALEGNSPY
1 month +2.3%-11.7%+15.7% -2.0%
3 months -11.3%-34.0%+12.3% -2.2%
6 months +11.6%-41.1%-24.7% +4.2%
Year to date +14.1%-25.6%-1.2% +10.6%
1 year +11.9%-8.3%-33.1% +10.4%
3 years +11.5%+64.9%-67.4% +73.6%
3 years, per year +3.7%+18.2%-31.2% +20.2%
5 years -15.6%-74.9%-55.9% +61.6%
5 years, per year -3.3%-24.1%-15.1% +10.1%
10 years +1,856.7%—— +261.3%
10 years, per year +34.6%—— +13.7%

Risk

MeasureVCELTSHALEGNSPY
Volatility, 1Y 41.3%70.8%72.4% 12.8%
Downside volatility, 1Y 41.1%68.1%62.7% 12.8%
Beta vs S&P 500, 1Y 0.771.830.48 1.00
Return / volatility, 1Y 0.29-0.12-0.46 0.81
Max drawdown, 5Y -63.7%-96.4%-78.2% -25.4%
From 52-week high -14.9%-41.4%-40.8% -3.2%
52-week high $48.31$6.98$36.28 $779.14
52-week low $29.34$3.51$16.65 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleVCELTSHALEGN
P/E now vs peer median 86.6xmedian 18.4x -10.1xmedian 18.4x -43.2xmedian 18.4x
P/S now vs peer median 6.9xmedian 9.0x 242.6xmedian 9.0x 3.1xmedian 9.0x
EV/EBITDA now vs peer median 61.8xmedian 16.0x -6.1xmedian 16.0x 867.8xmedian 16.0x
P/FCF now vs peer median 34.1xmedian 21.8x -10.0xmedian 21.8x -61.3xmedian 21.8x
P/B now vs peer median 5.7xmedian 2.1x 3.4xmedian 2.1x 3.2xmedian 2.1x
PEG now vs peer median 1.60median 0.37 -0.25median 0.37 -0.92median 0.37

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsVCELTSHALEGN
Revenue $306.30M $5.49M $1.27B
Gross profit $228.38M – $727.10M
Operating income $18.24M -$153.16M -$55.25M
Net income $24.22M -$149.63M -$80.39M
Free cash flow $61.66M -$132.57M -$64.60M
R&D $29.17M $123.14M $396.15M
EPS (diluted) $0.46 $-0.41 $-0.50
Cash & equivalents $125.40M $455.41M $672.90M
Total debt – $49.26M $156.40M
Shares (diluted) 52.31M 369.04M 184.32M
Enterprise value $1.74B $256.22M $1.73B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricVCELTSHALEGN
P/E 86.6x -10.1x -43.2x
P/FCF 34.1x -10.0x -61.3x
P/Operating cash flow 30.2x -10.1x -44.3x
P/S 6.9x 242.6x 3.1x
P/B 5.7x 3.4x 3.2x
P/Tangible book 5.8x 3.4x 3.2x
EV/EBITDA 61.8x -6.1x 867.8x
EV/EBIT 106.4x -6.0x -62.3x
EV/Revenue 6.3x 168.5x 2.7x
EV/FCF 31.5x -7.0x -53.3x
EV/Operating cash flow 27.8x -7.0x -38.5x
PEG (3Y EPS CAGR) 1.60 -0.25 -0.92

Growth

14 metrics
MetricVCELTSHALEGN
Revenue growth (1Y) 23.0% -32.3% 59.5%
Revenue CAGR (3Y) 19.8% -9.1% 97.6%
Gross profit growth (1Y) 24.8% – 42.4%
Gross profit CAGR (3Y) 23.9% – 147.5%
Operating income growth (1Y) 1,428% -62.9% 75.3%
Operating income CAGR (3Y) 47.8% -8.7% 49.1%
Net income growth (1Y) 240.8% -61.4% 75.3%
Net income CAGR (3Y) 56.6% -6.5% 46.7%
EPS growth (1Y) 228.1% -30.3% 72.0%
EPS CAGR (3Y) 54.3% 40.5% 47.0%
Operating cash flow growth (1Y) 47.5% -61.0% 67.5%
Operating cash flow CAGR (3Y) 33.7% -35.6% 37.1%
Free cash flow growth (1Y) 842.9% -60.6% 77.8%
Free cash flow CAGR (3Y) 43.2% -29.4% 44.5%

Profitability

14 metrics
MetricVCELTSHALEGN
Gross margin 74.6% – 57.2%
EBITDA margin 10.2% -2,770% 0.3%
Operating margin 6.0% -2,792% -4.3%
Pretax margin 8.2% -2,593% -4.4%
Net margin 7.9% -2,728% -7.2%
FCF margin 20.1% -2,417% -5.1%
Operating cash flow margin 22.7% -2,410% -7.0%
Return on equity 6.9% -47.5% -8.3%
Return on assets 5.1% -36.9% -5.5%
Return on invested capital – – -4.2%
Return on capital employed 4.1% -42.6% -4.3%
Asset turnover 0.6x 0.0x 0.8x
Cash conversion (OCF / net income) 2.9x 0.9x 1.1x
Stock comp / revenue 12.2% 331.3% 5.2%

Financial Health

11 metrics
MetricVCELTSHALEGN
Debt / assets – 10.5% 8.9%
Debt / equity – 0.1x 0.1x
Net debt / EBITDA – 2.7x -130.2x
Debt / FCF – -0.4x -2.4x
Liabilities / assets 26.4% 17.7% 29.8%
Equity / assets 73.6% 82.3% 70.2%
Interest coverage 28.5x -3,647x -4.8x
Current ratio 5.0x 17.8x 3.0x
Quick ratio 4.5x 17.5x 1.7x
Cash ratio 3.1x 17.5x 1.7x
Altman Z-score 9.67 7.26 6.73

Shareholder Returns

7 metrics
MetricVCELTSHALEGN
Dividend yield – – –
Net buyback yield -0.3% -0.2% -5.4%
Shareholder yield -0.3% -0.2% -5.4%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusVCELTSHALEGN
Forward P/E 80.6xFY2026 – –
EPS, next fiscal year $0.51FY2026 $-0.47FY2026 $-0.04FY2026
EPS growth, next FY +59.4%FY2026 – –
EPS growth, the year after +74.5% – –
Revenue, next fiscal year $324.56MFY2026 $1.96MFY2026 $1.37BFY2026
Revenue growth, next FY +17.5%FY2026 -80.0%FY2026 +32.9%FY2026
Revenue growth, the year after +16.1% +1,298.6% +35.9%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersVCELTSHALEGN
Held by institutions 100.0% 81.2% 55.9%
Institutions holding 319 209 218
Change in shares held, QoQ +0.4% +12.7% +7.3%
Institutions buying 188 140 117
Institutions selling 99 42 78
Buyers to sellers 1.90 3.33 1.50

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

VCELTSHALEGN
VCEL 1.00 0.19 0.14
TSHA 0.19 1.00 0.17
LEGN 0.14 0.17 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, VCEL, TSHA and LEGN?

Legend Biotech (LEGN) is the largest by market capitalisation: Vericel (VCEL) $2.32B, Taysha Gene Therapies (TSHA) $1.61B, Legend Biotech (LEGN) $4.23B.

Which company is growing faster?

Legend Biotech (LEGN) grew revenue fastest over the trailing twelve months: Vericel (VCEL) +23.0%, Taysha Gene Therapies (TSHA) -32.3%, Legend Biotech (LEGN) +59.5%.

Which company is more profitable?

Vericel (VCEL) has the highest net margin (Vericel (VCEL) 7.9%, Taysha Gene Therapies (TSHA) -2,728.0%, Legend Biotech (LEGN) -7.2%).

Which stock has performed better?

Over the past year Vericel (VCEL) returned the most: Vericel (VCEL) +11.9%, Taysha Gene Therapies (TSHA) -8.3%, Legend Biotech (LEGN) -33.1%. Over five years, Vericel (VCEL) compounded fastest (Vericel (VCEL) -3.3%/yr, Taysha Gene Therapies (TSHA) -24.1%/yr, Legend Biotech (LEGN) -15.1%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Vericel (VCEL) has been the steadiest (Vericel (VCEL) 41.3%, Taysha Gene Therapies (TSHA) 70.8%, Legend Biotech (LEGN) 72.4%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, VCEL, TSHA and LEGN?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Vericel (VCEL) leads on 5. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.