SRPT vs TSHA vs VCEL Stock Comparison

Sarepta Therapeutics, Taysha Gene Therapies and Vericel Prices as of Oct 29, 2026 Peers: Industry group
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VCEL Vericel Corp
$42.91 +5.7% 1M +23.0% 1Y
Market cap
$2.09B
P/E
86.2x
Revenue (TTM)
$306.30M
Div. yield
–
Gene and Cell Therapy Healthcare
7 wins

Head to Head

9 decided of 12

Vericel leads on 7 of the 12 questions below (Vericel 7, Sarepta Therapeutics 2). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionSRPTTSHAVCELLeader
Larger companyMarket capitalisation $1.96B $1.52B $2.09B VCEL
Cheaper on earningsLower P/E, profitable companies only -16.8x -10.1x 86.2x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS 6.7x — 84.1x SRPT
Faster revenue growthRevenue growth, trailing twelve months -20.4% -32.3% +23.0% VCEL
More profitableNet margin, trailing twelve months -5.9% -2,728.0% 7.9% VCEL
Better return on capitalReturn on invested capital -6.1% — — –
Less leveragedLower net debt / EBITDA -0.6x 2.7x — SRPT
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months -18.0% -15.8% +23.0% VCEL
Better 5-year returnAnnualised price return, 5 years -24.7%/yr -23.1%/yr -1.4%/yr VCEL
Less volatileAnnualised volatility, 1 year 81.1% 71.5% 41.0% VCEL
Higher overall scoreMean of the five percentile scores vs peers 67/100 49/100 81/100 VCEL

Percentile Scorecard

SRPTTSHAVCEL

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisSRPTTSHAVCEL
Valuation 97 #23 of 624 45 #343 of 624 82 #115 of 624
Growth 64 #220 of 601 16 #503 of 601 94 #36 of 601
Profitability 80 #111 of 541 28 #390 of 541 88 #64 of 541
Financial Health 34 #430 of 647 75 #160 of 647 69 #203 of 647
Shareholder Returns 61 #141 of 359 78 #79 of 359 73 #99 of 359
Overall 67 49 81
  • SRPT ranked among 671 companies in Pharmaceuticals and Biotechnology
  • TSHA ranked among 671 companies in Pharmaceuticals and Biotechnology
  • VCEL ranked among 671 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodSRPTTSHAVCELSPY
1 month +3.2%-15.4%+5.7% +0.7%
3 months +23.6%-28.2%-9.9% +3.7%
6 months -7.9%-34.0%+23.6% +7.1%
Year to date -10.6%-23.3%+19.2% +12.8%
1 year -18.0%-15.8%+23.0% +11.9%
3 years -82.1%+86.7%+24.8% +85.2%
3 years, per year -43.7%+23.2%+7.7% +22.8%
5 years -75.7%-73.0%-6.8% +67.6%
5 years, per year -24.7%-23.1%-1.4% +10.9%
10 years -53.0%—+1,726.0% +262.0%
10 years, per year -7.3%—+33.7% +13.7%

Risk

MeasureSRPTTSHAVCELSPY
Volatility, 1Y 81.1%71.5%41.0% 12.7%
Downside volatility, 1Y 85.8%69.5%40.0% 12.6%
Beta vs S&P 500, 1Y 2.081.820.71 1.00
Return / volatility, 1Y -0.22-0.220.56 0.94
Max drawdown, 5Y -92.7%-96.5%-64.7% -25.4%
From 52-week high -21.3%-39.5%-11.2% -1.2%
52-week high $24.45$6.98$48.31 $779.14
52-week low $14.86$3.51$29.34 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleSRPTTSHAVCEL
P/E now vs peer median -17.4xmedian 17.8x -10.4xmedian 17.8x 90.5xmedian 17.8x
P/S now vs peer median 1.0xmedian 9.1x 250.3xmedian 9.1x 7.2xmedian 9.1x
EV/EBITDA now vs peer median -21.2xmedian 15.0x -6.4xmedian 15.0x 64.8xmedian 15.0x
P/FCF now vs peer median 24.8xmedian 21.7x -10.4xmedian 21.7x 35.6xmedian 21.7x
P/B now vs peer median 1.3xmedian 2.2x 3.5xmedian 2.2x 5.9xmedian 2.2x
PEG now vs peer median -0.33median 0.35 -0.26median 0.35 1.67median 0.35

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsSRPTTSHAVCEL
Revenue $1.97B $5.49M $306.30M
Gross profit $1.17B – $228.38M
Operating income -$143.25M -$153.16M $18.24M
Net income -$136.73M -$149.63M $24.22M
Free cash flow $81.85M -$132.57M $61.66M
R&D $789.44M $123.14M $29.17M
EPS (diluted) $-1.11 $-0.41 $0.46
Cash & equivalents $571.15M $455.41M $125.40M
Total debt $847.62M $49.26M –
Shares (diluted) 105.43M 369.04M 52.31M
Enterprise value -$1.27B $169.50M $1.51B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricSRPTTSHAVCEL
P/E -17.4x -10.4x 90.5x
P/FCF 24.8x -10.4x 35.6x
P/Operating cash flow 18.3x -10.4x 31.5x
P/S 1.0x 250.3x 7.2x
P/B 1.3x 3.5x 5.9x
P/Tangible book 1.4x 3.5x 6.0x
EV/EBITDA -21.2x -6.4x 64.8x
EV/EBIT -14.6x -6.3x 111.5x
EV/Revenue 1.1x 176.2x 6.6x
EV/FCF 25.5x -7.3x 33.0x
EV/Operating cash flow 18.8x -7.3x 29.2x
PEG (3Y EPS CAGR) -0.33 -0.26 1.67

Growth

14 metrics
MetricSRPTTSHAVCEL
Revenue growth (1Y) -20.4% -32.3% 23.0%
Revenue CAGR (3Y) 25.3% -9.1% 19.8%
Gross profit growth (1Y) -40.7% – 24.8%
Gross profit CAGR (3Y) 10.6% – 23.9%
Operating income growth (1Y) -15,270% -62.9% 1,428%
Operating income CAGR (3Y) 34.5% -8.7% 47.8%
Net income growth (1Y) -135.9% -61.4% 240.8%
Net income CAGR (3Y) 46.8% -6.5% 56.6%
EPS growth (1Y) -215.7% -30.3% 228.1%
EPS CAGR (3Y) 52.3% 40.5% 54.3%
Operating cash flow growth (1Y) 136.9% -61.0% 47.5%
Operating cash flow CAGR (3Y) 30.6% -35.6% 33.7%
Free cash flow growth (1Y) 118.1% -60.6% 842.9%
Free cash flow CAGR (3Y) 29.1% -29.4% 43.2%

Profitability

14 metrics
MetricSRPTTSHAVCEL
Gross margin 59.1% – 74.6%
EBITDA margin -5.0% -2,770% 10.2%
Operating margin -7.3% -2,792% 6.0%
Pretax margin -6.6% -2,593% 8.2%
Net margin -5.9% -2,728% 7.9%
FCF margin 4.1% -2,417% 20.1%
Operating cash flow margin 5.6% -2,410% 22.7%
Return on equity -9.0% -47.5% 6.9%
Return on assets -4.3% -36.9% 5.1%
Return on invested capital -6.1% – –
Return on capital employed -5.3% -42.6% 4.1%
Asset turnover 0.6x 0.0x 0.6x
Cash conversion (OCF / net income) -0.8x 0.9x 2.9x
Stock comp / revenue 6.3% 331.3% 12.2%

Financial Health

11 metrics
MetricSRPTTSHAVCEL
Debt / assets 26.6% 10.5% –
Debt / equity 0.6x 0.1x –
Net debt / EBITDA -0.6x 2.7x –
Debt / FCF 10.4x -0.4x –
Liabilities / assets 52.1% 17.7% 26.4%
Equity / assets 47.9% 82.3% 73.6%
Interest coverage – -3,647x 28.5x
Current ratio 4.4x 17.8x 5.0x
Quick ratio 2.4x 17.5x 4.5x
Cash ratio 1.6x 17.5x 3.1x
Altman Z-score -0.15 7.57 10.09

Shareholder Returns

7 metrics
MetricSRPTTSHAVCEL
Dividend yield – – –
Net buyback yield -1.1% -0.2% -0.3%
Shareholder yield -1.1% -0.2% -0.3%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusSRPTTSHAVCEL
Forward P/E 6.7xFY2026 – 84.1xFY2026
EPS, next fiscal year $2.88FY2026 $-0.47FY2026 $0.51FY2026
EPS growth, next FY – – +59.4%FY2026
EPS growth, the year after -88.5% – +74.5%
Revenue, next fiscal year $1.76BFY2026 $1.96MFY2026 $324.56MFY2026
Revenue growth, next FY -20.1%FY2026 -80.0%FY2026 +17.5%FY2026
Revenue growth, the year after -21.5% +1,298.6% +16.1%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersSRPTTSHAVCEL
Held by institutions 100.0% 81.2% 100.0%
Institutions holding 325 209 318
Change in shares held, QoQ +4.5% +12.7% +0.4%
Institutions buying 148 140 188
Institutions selling 116 42 98
Buyers to sellers 1.28 3.33 1.92

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

SRPTTSHAVCEL
SRPT 1.00 0.36 0.19
TSHA 0.36 1.00 0.17
VCEL 0.19 0.17 1.00

Add a Peer

Largest companies in the same industry

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Frequently Asked Questions

Which is bigger, SRPT, TSHA and VCEL?

Vericel (VCEL) is the largest by market capitalisation: Sarepta Therapeutics (SRPT) $1.96B, Taysha Gene Therapies (TSHA) $1.52B, Vericel (VCEL) $2.09B.

Which company is growing faster?

Vericel (VCEL) grew revenue fastest over the trailing twelve months: Sarepta Therapeutics (SRPT) -20.4%, Taysha Gene Therapies (TSHA) -32.3%, Vericel (VCEL) +23.0%.

Which company is more profitable?

Vericel (VCEL) has the highest net margin (Sarepta Therapeutics (SRPT) -5.9%, Taysha Gene Therapies (TSHA) -2,728.0%, Vericel (VCEL) 7.9%).

Which stock has performed better?

Over the past year Vericel (VCEL) returned the most: Sarepta Therapeutics (SRPT) -18.0%, Taysha Gene Therapies (TSHA) -15.8%, Vericel (VCEL) +23.0%. Over five years, Vericel (VCEL) compounded fastest (Sarepta Therapeutics (SRPT) -24.7%/yr, Taysha Gene Therapies (TSHA) -23.1%/yr, Vericel (VCEL) -1.4%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Vericel (VCEL) has been the steadiest (Sarepta Therapeutics (SRPT) 81.1%, Taysha Gene Therapies (TSHA) 71.5%, Vericel (VCEL) 41.0%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, SRPT, TSHA and VCEL?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Vericel (VCEL) leads on 7. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.