PGEN vs LEGN vs VCEL Stock Comparison

Precigen, Legend Biotech and Vericel Prices as of Nov 5, 2026 Peers: Industry group
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PGEN Precigen, Inc.
$4.22 -44.1% 1M +5.8% 1Y
Market cap
$1.51B
P/E
61.9x
Revenue (TTM)
$156.94M
Div. yield
–
Gene and Cell Therapy Healthcare
5 wins
LEGN Legend Biotech Corp
$22.54 +20.4% 1M -29.6% 1Y
Market cap
$4.15B
P/E
–
Revenue (TTM)
$1.27B
Div. yield
–
Gene and Cell Therapy Healthcare
2 wins
VCEL Vericel Corp
$51.78 +29.3% 1M +39.2% 1Y
Market cap
$2.64B
P/E
79.6x
Revenue (TTM)
$324.17M
Div. yield
–
Gene and Cell Therapy Healthcare
4 wins

Head to Head

11 decided of 12

Precigen leads on 5 of the 12 questions below (Precigen 5, Vericel 4, Legend Biotech 2). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionPGENLEGNVCELLeader
Larger companyMarket capitalisation $1.51B $4.15B $2.64B LEGN
Cheaper on earningsLower P/E, profitable companies only 61.9x -45.3x 79.6x PGEN
Cheaper on forward earningsLower price / next fiscal year consensus EPS 24.8x — 101.5x PGEN
Faster revenue growthRevenue growth, trailing twelve months +2,387.6% +59.5% +25.3% PGEN
More profitableNet margin, trailing twelve months 15.6% -7.2% 10.3% PGEN
Better return on capitalReturn on invested capital 21.1% -4.2% — PGEN
Less leveragedLower net debt / EBITDA 1.2x -130.2x — LEGN
Higher dividend yieldTrailing dividend yield — — — –
Better 1-year returnPrice return, last 12 months +5.8% -29.6% +39.2% VCEL
Better 5-year returnAnnualised price return, 5 years -3.8%/yr -14.3%/yr +2.4%/yr VCEL
Less volatileAnnualised volatility, 1 year 85.7% 72.7% 44.3% VCEL
Higher overall scoreMean of the five percentile scores vs peers 72/100 74/100 81/100 VCEL

Percentile Scorecard

PGENLEGNVCEL

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisPGENLEGNVCEL
Valuation 68 #206 of 634 88 #77 of 634 81 #123 of 634
Growth 90 #59 of 608 96 #23 of 608 94 #39 of 608
Profitability 86 #81 of 557 80 #110 of 557 89 #65 of 557
Financial Health 38 #409 of 654 59 #267 of 654 70 #195 of 654
Shareholder Returns 77 #92 of 403 44 #225 of 403 73 #109 of 403
Overall 72 74 81
  • PGEN ranked among 671 companies in Pharmaceuticals and Biotechnology
  • LEGN ranked among 671 companies in Pharmaceuticals and Biotechnology
  • VCEL ranked among 671 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodPGENLEGNVCELSPY
1 month -44.1%+20.4%+29.3% -5.9%
3 months -38.9%+16.9%+15.7% -4.6%
6 months +1.7%-21.1%+47.4% +0.2%
Year to date +1.0%+3.7%+43.8% +7.5%
1 year +5.8%-29.6%+39.2% +8.2%
3 years +263.8%-65.8%+43.2% +68.3%
3 years, per year +53.8%-30.1%+12.7% +19.0%
5 years -17.4%-53.7%+12.4% +56.5%
5 years, per year -3.8%-14.3%+2.4% +9.4%
10 years -83.2%—+2,308.4% +251.5%
10 years, per year -16.4%—+37.5% +13.4%

Risk

MeasurePGENLEGNVCELSPY
Volatility, 1Y 85.7%72.7%44.3% 13.6%
Downside volatility, 1Y 84.2%62.9%41.2% 14.2%
Beta vs S&P 500, 1Y 1.630.500.43 1.00
Return / volatility, 1Y 0.07-0.410.88 0.60
Max drawdown, 5Y -86.5%-78.2%-60.2% -25.4%
From 52-week high -50.7%-37.9%0.0% -5.9%
52-week high $8.56$36.28$51.78 $779.14
52-week low $3.10$16.65$29.34 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultiplePGENLEGNVCEL
P/E now vs peer median 61.9xmedian 17.8x -45.3xmedian 17.8x 79.6xmedian 17.8x
P/S now vs peer median 9.6xmedian 8.1x 3.3xmedian 8.1x 8.2xmedian 8.1x
EV/EBITDA now vs peer median 39.6xmedian 15.7x 917.1xmedian 15.7x 60.6xmedian 15.7x
P/FCF now vs peer median -20.4xmedian 21.0x -64.3xmedian 21.0x 45.7xmedian 21.0x
P/B now vs peer median 18.1xmedian 2.0x 3.4xmedian 2.0x 6.9xmedian 2.0x
PEG now vs peer median 2.10median 0.36 -0.96median 0.36 1.13median 0.36

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsPGENLEGNVCEL
Revenue $156.94M $1.27B $324.17M
Gross profit $143.48M $727.10M $241.41M
Operating income $33.63M -$55.25M $26.97M
Net income $24.41M -$80.39M $33.31M
Free cash flow -$74.32M -$64.60M $57.89M
R&D $26.54M $396.15M $29.74M
EPS (diluted) $0.06 $-0.50 $0.63
Cash & equivalents $14.96M $672.90M $133.50M
Total debt $94.26M $156.40M –
Shares (diluted) 421.16M 184.32M 52.96M
Enterprise value $1.27B $1.65B $2.03B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricPGENLEGNVCEL
P/E 61.9x -45.3x 79.6x
P/FCF -20.4x -64.3x 45.7x
P/Operating cash flow -20.7x -46.5x 40.5x
P/S 9.6x 3.3x 8.2x
P/B 18.1x 3.4x 6.9x
P/Tangible book 18.5x 3.4x 7.0x
EV/EBITDA 39.6x 917.1x 60.6x
EV/EBIT 46.4x -65.8x 91.7x
EV/Revenue 9.9x 2.9x 7.6x
EV/FCF -21.0x -56.3x 42.7x
EV/Operating cash flow -21.3x -40.7x 37.9x
PEG (3Y EPS CAGR) 2.10 -0.96 1.13

Growth

14 metrics
MetricPGENLEGNVCEL
Revenue growth (1Y) 2,388% 59.5% 25.3%
Revenue CAGR (3Y) 185.3% 97.6% 20.5%
Gross profit growth (1Y) 7,400% 42.4% 26.4%
Gross profit CAGR (3Y) 478.3% 147.5% 24.4%
Operating income growth (1Y) 128.7% 75.3% 279.4%
Operating income CAGR (3Y) 33.6% 49.1% 59.5%
Net income growth (1Y) 109.9% 75.3% 154.6%
Net income CAGR (3Y) 31.8% 46.7% 73.8%
EPS growth (1Y) 104.2% 72.0% 149.5%
EPS CAGR (3Y) 29.5% 47.0% 70.1%
Operating cash flow growth (1Y) -0.8% 67.5% 10.4%
Operating cash flow CAGR (3Y) -3.2% 37.1% 26.6%
Free cash flow growth (1Y) 1.7% 77.8% 184.1%
Free cash flow CAGR (3Y) -3.5% 44.5% 45.2%

Profitability

14 metrics
MetricPGENLEGNVCEL
Gross margin 91.4% 57.2% 74.5%
EBITDA margin 25.1% 0.3% 12.6%
Operating margin 21.4% -4.3% 8.3%
Pretax margin 15.7% -4.4% 10.5%
Net margin 15.6% -7.2% 10.3%
FCF margin -47.4% -5.1% 17.9%
Operating cash flow margin -46.6% -7.0% 20.1%
Return on equity 38.3% -8.3% 9.1%
Return on assets 12.8% -5.5% 6.7%
Return on invested capital 21.1% -4.2% –
Return on capital employed 21.0% -4.3% 5.9%
Asset turnover 0.8x 0.8x 0.6x
Cash conversion (OCF / net income) -3.0x 1.1x 2.0x
Stock comp / revenue 8.0% 5.2% 11.3%

Financial Health

11 metrics
MetricPGENLEGNVCEL
Debt / assets 44.4% 8.9% –
Debt / equity 1.1x 0.1x –
Net debt / EBITDA 1.2x -130.2x –
Debt / FCF -1.3x -2.4x –
Liabilities / assets 60.5% 29.8% 25.7%
Equity / assets 39.5% 70.2% 74.3%
Interest coverage 2.8x -4.8x 42.0x
Current ratio 5.6x 3.0x 5.1x
Quick ratio 4.6x 1.7x 4.6x
Cash ratio 1.5x 1.7x 3.1x
Altman Z-score -6.00 6.95 12.26

Shareholder Returns

7 metrics
MetricPGENLEGNVCEL
Dividend yield – – –
Net buyback yield -0.2% -5.2% -0.3%
Shareholder yield -0.2% -5.2% -0.3%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusPGENLEGNVCEL
Forward P/E 24.8xFY2026 – 101.5xFY2026
EPS, next fiscal year $0.17FY2026 $-0.04FY2026 $0.51FY2026
EPS growth, next FY – – +59.4%FY2026
EPS growth, the year after +288.2% – +74.5%
Revenue, next fiscal year $249.16MFY2026 $1.37BFY2026 $324.56MFY2026
Revenue growth, next FY +2,474.0%FY2026 +32.9%FY2026 +17.5%FY2026
Revenue growth, the year after +82.3% +35.9% +16.1%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersPGENLEGNVCEL
Held by institutions 39.2% 55.9% 100.0%
Institutions holding 211 218 319
Change in shares held, QoQ +4.9% +7.3% +0.4%
Institutions buying 123 117 188
Institutions selling 46 78 99
Buyers to sellers 2.67 1.50 1.90

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

PGENLEGNVCEL
PGEN 1.00 0.07 0.06
LEGN 0.07 1.00 0.14
VCEL 0.06 0.14 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, PGEN, LEGN and VCEL?

Legend Biotech (LEGN) is the largest by market capitalisation: Precigen (PGEN) $1.51B, Legend Biotech (LEGN) $4.15B, Vericel (VCEL) $2.64B.

Which stock is cheaper, PGEN, LEGN and VCEL?

Precigen (PGEN) trades on the lowest price-to-earnings ratio (Precigen (PGEN) 61.9x, Legend Biotech (LEGN) -45.3x, Vericel (VCEL) 79.6x). On next year's consensus earnings, Precigen (PGEN) is cheapest (Precigen (PGEN) 24.8x, Vericel (VCEL) 101.5x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Precigen (PGEN) grew revenue fastest over the trailing twelve months: Precigen (PGEN) +2,387.6%, Legend Biotech (LEGN) +59.5%, Vericel (VCEL) +25.3%.

Which company is more profitable?

Precigen (PGEN) has the highest net margin (Precigen (PGEN) 15.6%, Legend Biotech (LEGN) -7.2%, Vericel (VCEL) 10.3%). On return on invested capital, Precigen (PGEN) leads (Precigen (PGEN) 21.1%, Legend Biotech (LEGN) -4.2%).

Which stock has performed better?

Over the past year Vericel (VCEL) returned the most: Precigen (PGEN) +5.8%, Legend Biotech (LEGN) -29.6%, Vericel (VCEL) +39.2%. Over five years, Vericel (VCEL) compounded fastest (Precigen (PGEN) -3.8%/yr, Legend Biotech (LEGN) -14.3%/yr, Vericel (VCEL) +2.4%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Vericel (VCEL) has been the steadiest (Precigen (PGEN) 85.7%, Legend Biotech (LEGN) 72.7%, Vericel (VCEL) 44.3%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, PGEN, LEGN and VCEL?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Precigen (PGEN) leads on 5. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.