ISRG vs PEN vs ABT Stock Comparison

Intuitive Surgical, Penumbra and Abbott Laboratories Prices as of Nov 2, 2026 Peers: Industry group
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ISRG Intuitive Surgical Inc
$436.87 +11.5% 1M -18.2% 1Y
Market cap
$151.42B
P/E
51.6x
Revenue (TTM)
$11.58B
Div. yield
–
Medical Devices Healthcare
4 wins
PEN Penumbra Inc
$321.35 +1.2% 1M +41.3% 1Y
Market cap
$12.67B
P/E
80.6x
Revenue (TTM)
$1.56B
Div. yield
–
Medical Devices Healthcare
2 wins
ABT Abbott Laboratories
$110.27 +13.1% 1M -10.8% 1Y
Market cap
$190.81B
P/E
35.4x
Revenue (TTM)
$46.59B
Div. yield
2.29%
Medical Devices Healthcare
3 wins

Head to Head

9 decided of 12

Intuitive Surgical leads on 4 of the 12 questions below (Intuitive Surgical 4, Abbott Laboratories 3, Penumbra 2). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionISRGPENABTLeader
Larger companyMarket capitalisation $151.42B $12.67B $190.81B ABT
Cheaper on earningsLower P/E, profitable companies only 51.6x 80.6x 35.4x ABT
Cheaper on forward earningsLower price / next fiscal year consensus EPS 38.1x 71.7x 19.4x ABT
Faster revenue growthRevenue growth, trailing twelve months +20.5% +17.0% +8.1% ISRG
More profitableNet margin, trailing twelve months 25.5% 10.1% 11.6% ISRG
Better return on capitalReturn on invested capital — — 6.2% –
Less leveragedLower net debt / EBITDA — — 2.5x –
Higher dividend yieldTrailing dividend yield — — 2.29% –
Better 1-year returnPrice return, last 12 months -18.2% +41.3% -10.8% PEN
Better 5-year returnAnnualised price return, 5 years +3.9%/yr +3.0%/yr -3.0%/yr ISRG
Less volatileAnnualised volatility, 1 year 34.8% 25.8% 27.8% PEN
Higher overall scoreMean of the five percentile scores vs peers 79/100 73/100 57/100 ISRG

Percentile Scorecard

ISRGPENABT

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisISRGPENABT
Valuation 50 #113 of 227 53 #107 of 227 67 #76 of 227
Growth 79 #47 of 220 86 #32 of 220 28 #158 of 220
Profitability 97 #7 of 209 86 #31 of 209 85 #33 of 209
Financial Health 78 #54 of 240 86 #34 of 240 37 #152 of 240
Shareholder Returns 92 #12 of 138 55 #63 of 138 66 #47 of 138
Overall 79 73 57
  • ISRG ranked among 247 companies in Medical Devices and Diagnostics
  • PEN ranked among 247 companies in Medical Devices and Diagnostics
  • ABT ranked among 247 companies in Medical Devices and Diagnostics

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodISRGPENABTSPY
1 month +11.5%+1.2%+13.1% -2.3%
3 months +16.4%-0.5%+2.9% -0.7%
6 months -3.4%-1.0%+26.0% +4.8%
Year to date -22.9%+3.4%-12.0% +10.3%
1 year -18.2%+41.3%-10.8% +10.3%
3 years +56.9%+62.4%+15.1% +73.0%
3 years, per year +16.2%+17.6%+4.8% +20.1%
5 years +20.9%+15.9%-14.3% +61.9%
5 years, per year +3.9%+3.0%-3.0% +10.1%
10 years +489.9%+421.7%+184.9% +258.6%
10 years, per year +19.4%+18.0%+11.0% +13.6%

Risk

MeasureISRGPENABTSPY
Volatility, 1Y 34.8%25.8%27.8% 12.8%
Downside volatility, 1Y 37.8%16.2%27.6% 12.8%
Beta vs S&P 500, 1Y 0.900.06-0.04 1.00
Return / volatility, 1Y -0.521.60-0.39 0.80
Max drawdown, 5Y -49.9%-59.7%-41.6% -25.4%
From 52-week high -26.3%-10.6%-15.6% -3.5%
52-week high $592.85$359.40$130.59 $779.14
52-week low $332.02$225.54$82.56 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleISRGPENABT
P/E now vs peer median 51.6xmedian 28.4x 80.6xmedian 28.4x 35.4xmedian 28.4x
P/S now vs peer median 13.1xmedian 3.0x 8.1xmedian 3.0x 4.1xmedian 3.0x
EV/EBITDA now vs peer median 36.0xmedian 18.0x 57.3xmedian 18.0x 20.2xmedian 18.0x
P/FCF now vs peer median 42.1xmedian 25.0x 63.2xmedian 25.0x 24.4xmedian 25.0x
P/B now vs peer median 9.4xmedian 2.3x 8.0xmedian 2.3x 3.7xmedian 2.3x
PEG now vs peer median 2.01median 0.93 1.43median 0.93 19.46median 0.93

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsISRGPENABT
Revenue $11.58B $1.56B $46.59B
Gross profit $7.78B $1.06B $26.37B
Operating income $3.28B $189.25M $7.35B
Net income $2.97B $157.02M $5.43B
Free cash flow $3.60B $200.29M $7.82B
R&D $1.49B $94.93M $3.16B
EPS (diluted) $8.41 $3.96 $3.11
Cash & equivalents $2.98B $254.28M $5.10B
Total debt – – $32.61B
Shares (diluted) 351.60M 39.62M 1.74B
Enterprise value $131.84B $10.17B $161.89B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricISRGPENABT
P/E 51.6x 80.6x 35.4x
P/FCF 42.1x 63.2x 24.4x
P/Operating cash flow 37.0x 48.5x 19.3x
P/S 13.1x 8.1x 4.1x
P/B 9.4x 8.0x 3.7x
P/Tangible book 10.2x 8.0x 5.5x
EV/EBITDA 36.0x 57.3x 20.2x
EV/EBIT 44.9x 63.4x 29.7x
EV/Revenue 12.7x 7.7x 4.7x
EV/FCF 41.0x 59.9x 27.8x
EV/Operating cash flow 36.0x 45.9x 22.0x
PEG (3Y EPS CAGR) 2.01 1.43 19.46

Growth

14 metrics
MetricISRGPENABT
Revenue growth (1Y) 20.5% 17.0% 8.1%
Revenue CAGR (3Y) 19.1% 16.2% 5.0%
Gross profit growth (1Y) 21.9% 19.1% 9.2%
Gross profit CAGR (3Y) 19.5% 18.7% 5.9%
Operating income growth (1Y) 16.6% 9.5% -2.2%
Operating income CAGR (3Y) 24.8% 63.4% 6.2%
Net income growth (1Y) 7.5% -4.3% -61.2%
Net income CAGR (3Y) 24.4% 56.9% 1.7%
EPS growth (1Y) 10.8% -5.0% -61.0%
EPS CAGR (3Y) 25.7% 56.4% 1.8%
Operating cash flow growth (1Y) 38.1% 28.4% 9.6%
Operating cash flow CAGR (3Y) 26.4% 61.1% 9.9%
Free cash flow growth (1Y) 58.4% 31.2% 15.5%
Free cash flow CAGR (3Y) 42.0% 61.8% 12.5%

Profitability

14 metrics
MetricISRGPENABT
Gross margin 67.2% 68.0% 56.6%
EBITDA margin 35.3% 13.4% 23.2%
Operating margin 28.4% 12.1% 15.8%
Pretax margin 31.3% 13.3% 16.1%
Net margin 25.5% 10.1% 11.6%
FCF margin 31.1% 12.8% 16.8%
Operating cash flow margin 35.3% 16.7% 21.3%
Return on equity 17.3% 10.1% 10.4%
Return on assets 14.8% 7.8% 4.9%
Return on invested capital – – 6.2%
Return on capital employed 18.7% 10.7% 8.0%
Asset turnover 0.6x 0.8x 0.4x
Cash conversion (OCF / net income) 1.4x 1.7x 1.8x
Stock comp / revenue 7.2% 3.7% 1.5%

Financial Health

11 metrics
MetricISRGPENABT
Debt / assets – – 29.9%
Debt / equity – – 0.6x
Net debt / EBITDA – – 2.5x
Debt / FCF – – 4.2x
Liabilities / assets 16.7% 21.8% 52.6%
Equity / assets 83.3% 78.2% 47.4%
Interest coverage – – 9.6x
Current ratio 3.3x 5.9x 1.4x
Quick ratio 2.3x 3.7x 0.8x
Cash ratio 1.6x 2.9x 0.3x
Altman Z-score 29.97 19.21 3.35

Shareholder Returns

7 metrics
MetricISRGPENABT
Dividend yield – – 2.3%
Net buyback yield 2.8% -0.1% 0.9%
Shareholder yield 2.8% -0.1% 3.1%
Payout ratio (earnings) – – 78.5%
Payout ratio (FCF) – – 54.5%
Dividend growth (1Y) – – 7.2%
Dividend CAGR (3Y) – – 7.5%

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusISRGPENABT
Forward P/E 38.1xFY2026 71.7xFY2026 19.4xFY2026
EPS, next fiscal year $11.47FY2026 $4.48FY2026 $5.69FY2026
EPS growth, next FY +28.4%FY2026 +16.7%FY2026 +10.5%FY2026
EPS growth, the year after +4.5% +42.6% +10.4%
Revenue, next fiscal year $11.60BFY2026 $1.63BFY2026 $53.00BFY2026
Revenue growth, next FY +15.3%FY2026 +16.3%FY2026 +19.5%FY2026
Revenue growth, the year after +11.3% +7.5% -2.2%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersISRGPENABT
Held by institutions 86.2% 86.6% 79.2%
Institutions holding 2,238 451 2,982
Change in shares held, QoQ +4.6% +0.9% +0.3%
Institutions buying 1,072 195 1,260
Institutions selling 878 182 1,379
Buyers to sellers 1.22 1.07 0.91

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

ISRGPENABT
ISRG 1.00 0.13 0.32
PEN 0.13 1.00 0.14
ABT 0.32 0.14 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, ISRG, PEN and ABT?

Abbott Laboratories (ABT) is the largest by market capitalisation: Intuitive Surgical (ISRG) $151.42B, Penumbra (PEN) $12.67B, Abbott Laboratories (ABT) $190.81B.

Which stock is cheaper, ISRG, PEN and ABT?

Abbott Laboratories (ABT) trades on the lowest price-to-earnings ratio (Intuitive Surgical (ISRG) 51.6x, Penumbra (PEN) 80.6x, Abbott Laboratories (ABT) 35.4x). On next year's consensus earnings, Abbott Laboratories (ABT) is cheapest (Intuitive Surgical (ISRG) 38.1x, Penumbra (PEN) 71.7x, Abbott Laboratories (ABT) 19.4x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Intuitive Surgical (ISRG) grew revenue fastest over the trailing twelve months: Intuitive Surgical (ISRG) +20.5%, Penumbra (PEN) +17.0%, Abbott Laboratories (ABT) +8.1%.

Which company is more profitable?

Intuitive Surgical (ISRG) has the highest net margin (Intuitive Surgical (ISRG) 25.5%, Penumbra (PEN) 10.1%, Abbott Laboratories (ABT) 11.6%).

Which stock has performed better?

Over the past year Penumbra (PEN) returned the most: Intuitive Surgical (ISRG) -18.2%, Penumbra (PEN) +41.3%, Abbott Laboratories (ABT) -10.8%. Over five years, Intuitive Surgical (ISRG) compounded fastest (Intuitive Surgical (ISRG) +3.9%/yr, Penumbra (PEN) +3.0%/yr, Abbott Laboratories (ABT) -3.0%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Only one of these companies pays a dividend: Abbott Laboratories (ABT) 2.29%. Intuitive Surgical (ISRG) and Penumbra (PEN) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Penumbra (PEN) has been the steadiest (Intuitive Surgical (ISRG) 34.8%, Penumbra (PEN) 25.8%, Abbott Laboratories (ABT) 27.8%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, ISRG, PEN and ABT?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Intuitive Surgical (ISRG) leads on 4. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.