IOVA vs SLBT vs SLDB Stock Comparison

Iovance Biotherapeutics, SL Science Holding and Solid Biosciences Prices as of Nov 3, 2026 Peers: Industry group
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SLDB Solid Biosciences Inc.
$6.28 -8.3% 1M +20.8% 1Y
Market cap
$931.10M
P/E
–
Revenue (TTM)
—
Div. yield
–
Gene and Cell Therapy Healthcare
1 win

Head to Head

5 decided of 12

Iovance Biotherapeutics leads on 4 of the 12 questions below (Iovance Biotherapeutics 4, Solid Biosciences 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionIOVASLBTSLDBLeader
Larger companyMarket capitalisation $3.95B $2.59B $931.10M IOVA
Cheaper on earningsLower P/E, profitable companies only -13.6x — -4.5x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — — — –
Faster revenue growthRevenue growth, trailing twelve months +34.5% — — –
More profitableNet margin, trailing twelve months -89.1% — — –
Better return on capitalReturn on invested capital — — — –
Less leveragedLower net debt / EBITDA — — — –
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +352.8% -88.3% +20.8% IOVA
Better 5-year returnAnnualised price return, 5 years -18.5%/yr — -29.8%/yr IOVA
Less volatileAnnualised volatility, 1 year 109.4% 175.7% 78.3% SLDB
Higher overall scoreMean of the five percentile scores vs peers 63/100 — 44/100 IOVA

Percentile Scorecard

IOVASLBTSLDB

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisIOVASLBTSLDB
Valuation 65 #224 of 634 12 #561 of 634 39 #385 of 634
Growth 82 #111 of 607 – 21 #483 of 607
Profitability 63 #205 of 557 – 51 #275 of 557
Financial Health 62 #250 of 654 58 #278 of 654 88 #79 of 654
Shareholder Returns 41 #238 of 401 – 20 #321 of 401
Overall 63 – 44
  • IOVA ranked among 671 companies in Pharmaceuticals and Biotechnology
  • SLBT ranked among 671 companies in Pharmaceuticals and Biotechnology
  • SLDB ranked among 671 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodIOVASLBTSLDBSPY
1 month -37.9%-22.3%-8.3% -2.0%
3 months +102.5%-60.4%-27.1% -2.2%
6 months +121.9%-85.6%-9.0% +4.2%
Year to date +223.4%-88.4%+11.3% +10.6%
1 year +352.8%-88.3%+20.8% +10.4%
3 years +109.7%—+121.1% +73.6%
3 years, per year +28.0%—+30.3% +20.2%
5 years -64.0%—-83.0% +61.6%
5 years, per year -18.5%—-29.8% +10.1%
10 years +50.9%—— +261.3%
10 years, per year +4.2%—— +13.7%

Risk

MeasureIOVASLBTSLDBSPY
Volatility, 1Y 109.4%175.7%78.3% 12.8%
Downside volatility, 1Y 94.7%169.4%76.2% 12.8%
Beta vs S&P 500, 1Y 1.540.172.13 1.00
Return / volatility, 1Y 3.22-0.500.27 0.81
Max drawdown, 5Y -93.4%-91.0%-94.9% -25.4%
From 52-week high -40.6%-90.5%-43.7% -3.2%
52-week high $14.86$12.81$11.15 $779.14
52-week low $1.81$1.15$3.93 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleIOVASLBTSLDB
P/E now vs peer median -13.7xmedian 18.4x —median 18.4x -4.4xmedian 18.4x
P/S now vs peer median 12.3xmedian 9.0x —median 9.0x —median 9.0x
EV/EBITDA now vs peer median -14.0xmedian 16.0x —median 16.0x -2.5xmedian 16.0x
P/FCF now vs peer median -13.5xmedian 21.8x -1,417xmedian 21.8x -4.8xmedian 21.8x
P/B now vs peer median 5.4xmedian 2.1x 381.5xmedian 2.1x 2.4xmedian 2.1x
PEG now vs peer median -0.46median 0.37 —median 0.37 -0.14median 0.37

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsIOVASLBTSLDB
Revenue $324.97M – –
Gross profit $157.29M – –
Operating income -$301.31M – -$212.15M
Net income -$289.51M – -$207.10M
Free cash flow -$296.40M – -$187.82M
R&D $267.72M – $167.40M
EPS (diluted) $-0.64 – $-1.44
Cash & equivalents $110.80M $8.31M $159.39M
Shares (diluted) 450.19M – 143.69M
Enterprise value $2.74B $2.58B -$251.25M

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricIOVASLBTSLDB
P/E -13.7x – -4.4x
P/FCF -13.5x -1,417x -4.8x
P/Operating cash flow -15.1x – -4.8x
P/S 12.3x – –
P/B 5.4x 381.5x 2.4x
P/Tangible book 8.5x 381.5x 2.4x
EV/EBITDA -14.0x – -2.5x
EV/EBIT -12.3x – -2.5x
EV/Revenue 11.4x – –
EV/FCF -12.5x – -2.8x
EV/Operating cash flow -14.0x – -2.8x
PEG (3Y EPS CAGR) -0.46 – -0.14

Growth

14 metrics
MetricIOVASLBTSLDB
Revenue growth (1Y) 34.5% – –
Revenue CAGR (3Y) 1,009% – –
Gross profit growth (1Y) 95.1% – –
Gross profit CAGR (3Y) – – –
Operating income growth (1Y) 26.6% – -35.3%
Operating income CAGR (3Y) 11.1% – -22.8%
Net income growth (1Y) 25.8% – -34.4%
Net income CAGR (3Y) 11.6% – -31.9%
EPS growth (1Y) 44.8% – 11.9%
EPS CAGR (3Y) 29.9% – 32.0%
Operating cash flow growth (1Y) 12.9% – -52.4%
Operating cash flow CAGR (3Y) 7.6% – -19.2%
Free cash flow growth (1Y) 8.4% – -52.3%
Free cash flow CAGR (3Y) 5.8% – -18.4%

Profitability

14 metrics
MetricIOVASLBTSLDB
Gross margin 48.4% – –
EBITDA margin -81.4% – –
Operating margin -92.7% – –
Pretax margin -90.4% – –
Net margin -89.1% – –
FCF margin -91.2% – –
Operating cash flow margin -81.3% – –
Return on equity -39.7% – -55.4%
Return on assets -31.4% – -49.1%
Return on invested capital – – –
Return on capital employed -37.0% – -54.0%
Asset turnover 0.4x – –
Cash conversion (OCF / net income) 0.9x – 0.9x
Stock comp / revenue 14.4% – –

Financial Health

11 metrics
MetricIOVASLBTSLDB
Debt / assets – – –
Debt / equity – – –
Net debt / EBITDA – – –
Debt / FCF – – –
Liabilities / assets 19.6% 21.8% 11.1%
Equity / assets 80.4% 78.2% 88.9%
Interest coverage – – –
Current ratio 4.3x 4.4x 13.8x
Quick ratio 3.7x 4.3x 13.2x
Cash ratio 2.8x 4.3x 13.2x
Altman Z-score 8.67 – –

Shareholder Returns

7 metrics
MetricIOVASLBTSLDB
Dividend yield – – –
Net buyback yield -7.4% – -26.7%
Shareholder yield -7.4% 0.0% -26.7%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusIOVASLBTSLDB
EPS, next fiscal year $-0.47FY2026 – $-1.63FY2026
Revenue, next fiscal year $434.71MFY2026 – $0.00FY2026
Revenue growth, next FY +65.0%FY2026 – –
Revenue growth, the year after +33.0% – –

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersIOVASLBTSLDB
Held by institutions 63.3% – 79.7%
Institutions holding 292 – 157
Change in shares held, QoQ +6.5% – +18.9%
Institutions buying 174 – 101
Institutions selling 66 – 37
Buyers to sellers 2.64 – 2.73

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

IOVASLBTSLDB
IOVA 1.00 0.01 0.27
SLBT 0.01 1.00 -0.02
SLDB 0.27 -0.02 1.00

Add a Peer

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Frequently Asked Questions

Which is bigger, IOVA, SLBT and SLDB?

Iovance Biotherapeutics (IOVA) is the largest by market capitalisation: Iovance Biotherapeutics (IOVA) $3.95B, SL Science Holding (SLBT) $2.59B, Solid Biosciences (SLDB) $931.10M.

Which stock has performed better?

Over the past year Iovance Biotherapeutics (IOVA) returned the most: Iovance Biotherapeutics (IOVA) +352.8%, SL Science Holding (SLBT) -88.3%, Solid Biosciences (SLDB) +20.8%. Over five years, Iovance Biotherapeutics (IOVA) compounded fastest (Iovance Biotherapeutics (IOVA) -18.5%/yr, Solid Biosciences (SLDB) -29.8%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Solid Biosciences (SLDB) has been the steadiest (Iovance Biotherapeutics (IOVA) 109.4%, SL Science Holding (SLBT) 175.7%, Solid Biosciences (SLDB) 78.3%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, IOVA, SLBT and SLDB?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Iovance Biotherapeutics (IOVA) leads on 4. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.