CAI vs NEO vs GH Stock Comparison

Caris Life Sciences, Neogenomics and Guardant Health Prices as of Nov 4, 2026 Peers: Industry group
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NEO Neogenomics Inc
$17.15 -10.4% 1M +69.8% 1Y
Market cap
$2.11B
P/E
–
Revenue (TTM)
$787.75M
Div. yield
–
Diagnostic Labs Healthcare
1 win
GH Guardant Health, Inc.
$168.58 -10.0% 1M +71.8% 1Y
Market cap
$21.18B
P/E
–
Revenue (TTM)
$1.18B
Div. yield
–
Diagnostic Labs Healthcare
4 wins

Head to Head

8 decided of 12

Guardant Health leads on 4 of the 12 questions below (Guardant Health 4, Caris Life Sciences 3, Neogenomics 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionCAINEOGHLeader
Larger companyMarket capitalisation $7.35B $2.11B $21.18B GH
Cheaper on earningsLower P/E, profitable companies only 76.5x -65.2x -46.7x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS 302.0x 85.7x — NEO
Faster revenue growthRevenue growth, trailing twelve months +61.5% +11.1% +42.7% CAI
More profitableNet margin, trailing twelve months 9.2% -4.1% -38.3% CAI
Better return on capitalReturn on invested capital 13.7% — — –
Less leveragedLower net debt / EBITDA -2.3x — — –
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +6.5% +69.8% +71.8% GH
Better 5-year returnAnnualised price return, 5 years — -16.2%/yr +8.9%/yr GH
Less volatileAnnualised volatility, 1 year 69.8% 53.7% 52.0% GH
Higher overall scoreMean of the five percentile scores vs peers 65/100 42/100 28/100 CAI

Percentile Scorecard

CAINEOGH

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisCAINEOGH
Valuation 22 #74 of 95 30 #67 of 95 17 #79 of 95
Growth 99 #2 of 88 58 #38 of 88 45 #49 of 88
Profitability 71 #26 of 87 33 #59 of 87 7 #81 of 87
Financial Health 79 #22 of 100 69 #32 of 100 58 #43 of 100
Shareholder Returns 56 #26 of 58 19 #47 of 58 14 #50 of 58
Overall 65 42 28
  • CAI ranked among 102 companies in Healthcare Providers
  • NEO ranked among 102 companies in Healthcare Providers
  • GH ranked among 102 companies in Healthcare Providers

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodCAINEOGHSPY
1 month +9.3%-10.4%-10.0% -1.0%
3 months +101.9%+9.0%+3.3% -0.4%
6 months +73.7%+92.9%+82.7% +4.5%
Year to date +23.1%+45.8%+65.0% +12.4%
1 year +6.5%+69.8%+71.8% +13.6%
3 years —+12.3%+488.0% +76.4%
3 years, per year —+3.9%+80.6% +20.8%
5 years —-58.6%+53.0% +63.7%
5 years, per year —-16.2%+8.9% +10.4%
10 years —+114.1%— +267.7%
10 years, per year —+7.9%— +13.9%

Risk

MeasureCAINEOGHSPY
Volatility, 1Y 69.8%53.7%52.0% 12.8%
Downside volatility, 1Y 70.3%53.0%49.5% 12.7%
Beta vs S&P 500, 1Y 1.551.101.19 1.00
Return / volatility, 1Y 0.091.301.38 1.06
Max drawdown, 5Y -63.0%-88.9%-85.4% -25.4%
From 52-week high -8.1%-13.9%-10.0% -1.6%
52-week high $36.14$19.91$187.22 $779.14
52-week low $14.55$7.19$78.60 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleCAINEOGH
P/E now vs peer median 98.2xmedian 25.6x -68.3xmedian 25.6x -49.4xmedian 25.6x
P/S now vs peer median 9.1xmedian 1.6x 2.8xmedian 1.6x 19.0xmedian 1.6x
EV/EBITDA now vs peer median 55.0xmedian 16.0x 124.4xmedian 16.0x -49.7xmedian 16.0x
P/FCF now vs peer median 329.5xmedian 21.6x -77.5xmedian 21.6x -93.6xmedian 21.6x
P/B now vs peer median 14.9xmedian 3.4x 2.8xmedian 3.4x -101.1xmedian 3.4x
PEG now vs peer median —median 0.74 -2.20median 0.74 -4.97median 0.74

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsCAINEOGH
Revenue $1.05B $787.75M $1.18B
Gross profit $724.14M $352.67M $769.16M
Operating income $139.94M -$49.37M -$470.26M
Net income $96.06M -$32.30M -$453.44M
Free cash flow $28.91M -$28.58M -$240.72M
R&D $129.36M $39.33M $375.79M
EPS (diluted) $0.33 $-0.25 $-3.41
Cash & equivalents $665.32M $139.28M $1.05B
Total debt $393.27M – –
Shares (diluted) 295.14M 128.59M 132.87M
Enterprise value $4.17B $1.52B $17.24B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricCAINEOGH
P/E 98.2x -68.3x -49.4x
P/FCF 329.5x -77.5x -93.6x
P/Operating cash flow 113.5x 517.3x -121.6x
P/S 9.1x 2.8x 19.0x
P/B 14.9x 2.8x -101.1x
P/Tangible book 14.9x 4.1x -90.8x
EV/EBITDA 55.0x 124.4x -49.7x
EV/EBIT 65.4x -42.0x -45.7x
EV/Revenue 8.7x 2.6x 18.1x
EV/FCF 316.5x -72.6x -89.2x
EV/Operating cash flow 109.1x 484.8x -115.9x
PEG (3Y EPS CAGR) – -2.20 -4.97

Growth

14 metrics
MetricCAINEOGH
Revenue growth (1Y) 61.5% 11.1% 42.7%
Revenue CAGR (3Y) – 11.1% 32.4%
Gross profit growth (1Y) 86.2% 14.4% 47.7%
Gross profit CAGR (3Y) – 14.7% –
Operating income growth (1Y) 274.2% 59.2% -2.1%
Operating income CAGR (3Y) – 24.7% 4.8%
Net income growth (1Y) 151.4% 71.5% -9.6%
Net income CAGR (3Y) – 30.5% 3.7%
EPS growth (1Y) 114.2% 71.6% -2.4%
EPS CAGR (3Y) – 31.1% 9.9%
Operating cash flow growth (1Y) 15,464% -68.7% 22.4%
Operating cash flow CAGR (3Y) – 29.7% 18.1%
Free cash flow growth (1Y) 306.4% -67.7% 11.4%
Free cash flow CAGR (3Y) – 16.8% 14.4%

Profitability

14 metrics
MetricCAINEOGH
Gross margin 69.1% 44.8% 65.0%
EBITDA margin 15.9% 2.1% -36.5%
Operating margin 13.4% -6.3% -39.7%
Pretax margin 9.3% -4.6% -38.4%
Net margin 9.2% -4.1% -38.3%
FCF margin 2.8% -3.6% -20.3%
Operating cash flow margin 8.0% 0.5% -15.7%
Return on equity 15.6% -4.1% –
Return on assets 7.7% -2.4% -23.7%
Return on invested capital 13.7% – –
Return on capital employed 12.9% -4.0% -29.9%
Asset turnover 0.8x 0.6x 0.6x
Cash conversion (OCF / net income) 0.9x -0.1x 0.4x
Stock comp / revenue 6.7% 4.4% 16.2%

Financial Health

11 metrics
MetricCAINEOGH
Debt / assets 31.3% – –
Debt / equity 0.6x – –
Net debt / EBITDA -2.3x – –
Debt / FCF 13.6x – –
Liabilities / assets 49.1% 41.9% 111.7%
Equity / assets 50.9% 58.1% -11.7%
Interest coverage 3.3x -15.2x -97.6x
Current ratio 6.7x 3.5x 4.0x
Quick ratio 5.7x 3.0x 3.5x
Cash ratio 4.8x 1.2x 3.1x
Altman Z-score 8.52 2.55 4.42

Shareholder Returns

7 metrics
MetricCAINEOGH
Dividend yield – – –
Net buyback yield 0.0% -0.7% -1.8%
Shareholder yield 0.0% -0.7% -1.8%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusCAINEOGH
Forward P/E 302.0xFY2026 85.7xFY2026 –
EPS, next fiscal year $0.11FY2026 $0.20FY2026 $-3.33FY2026
EPS growth, next FY – +66.7%FY2026 –
EPS growth, the year after +236.4% +80.0% –
Revenue, next fiscal year $1.06BFY2026 $778.61MFY2026 $1.42BFY2026
Revenue growth, next FY +30.1%FY2026 +7.1%FY2026 +44.5%FY2026
Revenue growth, the year after +21.6% +6.5% +27.0%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersCAINEOGH
Held by institutions 52.0% 100.0% 100.0%
Institutions holding 246 266 597
Change in shares held, QoQ -6.3% +8.1% -2.5%
Institutions buying 175 156 356
Institutions selling 47 62 180
Buyers to sellers 3.72 2.52 1.98

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

CAINEOGH
CAI 1.00 0.45 0.44
NEO 0.45 1.00 0.49
GH 0.44 0.49 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, CAI, NEO and GH?

Guardant Health (GH) is the largest by market capitalisation: Caris Life Sciences (CAI) $7.35B, Neogenomics (NEO) $2.11B, Guardant Health (GH) $21.18B.

Which company is growing faster?

Caris Life Sciences (CAI) grew revenue fastest over the trailing twelve months: Caris Life Sciences (CAI) +61.5%, Neogenomics (NEO) +11.1%, Guardant Health (GH) +42.7%.

Which company is more profitable?

Caris Life Sciences (CAI) has the highest net margin (Caris Life Sciences (CAI) 9.2%, Neogenomics (NEO) -4.1%, Guardant Health (GH) -38.3%).

Which stock has performed better?

Over the past year Guardant Health (GH) returned the most: Caris Life Sciences (CAI) +6.5%, Neogenomics (NEO) +69.8%, Guardant Health (GH) +71.8%. Over five years, Guardant Health (GH) compounded fastest (Neogenomics (NEO) -16.2%/yr, Guardant Health (GH) +8.9%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Guardant Health (GH) has been the steadiest (Caris Life Sciences (CAI) 69.8%, Neogenomics (NEO) 53.7%, Guardant Health (GH) 52.0%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, CAI, NEO and GH?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Guardant Health (GH) leads on 4. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.