CAI vs GRAL vs NEO Stock Comparison

Caris Life Sciences, Grail and Neogenomics Prices as of Nov 4, 2026 Peers: Industry group
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GRAL GRAIL, Inc.
$143.66 -6.8% 1M +78.0% 1Y
Market cap
$6.42B
P/E
–
Revenue (TTM)
$157.21M
Div. yield
–
Diagnostic Labs Healthcare
1 win
NEO Neogenomics Inc
$17.15 -10.4% 1M +69.8% 1Y
Market cap
$2.21B
P/E
–
Revenue (TTM)
$787.75M
Div. yield
–
Diagnostic Labs Healthcare
2 wins

Head to Head

7 decided of 12

Caris Life Sciences leads on 4 of the 12 questions below (Caris Life Sciences 4, Neogenomics 2, Grail 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionCAIGRALNEOLeader
Larger companyMarket capitalisation $9.52B $6.42B $2.21B CAI
Cheaper on earningsLower P/E, profitable companies only 98.2x -15.8x -68.3x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS 302.0x — 85.7x NEO
Faster revenue growthRevenue growth, trailing twelve months +61.5% +17.1% +11.1% CAI
More profitableNet margin, trailing twelve months 9.2% -249.1% -4.1% CAI
Better return on capitalReturn on invested capital 13.7% — — –
Less leveragedLower net debt / EBITDA -2.3x — — –
Higher dividend yieldTrailing dividend yield 0.00% — — –
Better 1-year returnPrice return, last 12 months +6.5% +78.0% +69.8% GRAL
Better 5-year returnAnnualised price return, 5 years — — -16.2%/yr –
Less volatileAnnualised volatility, 1 year 69.8% 111.5% 53.7% NEO
Higher overall scoreMean of the five percentile scores vs peers 65/100 41/100 42/100 CAI

Percentile Scorecard

CAIGRALNEO

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisCAIGRALNEO
Valuation 22 #74 of 95 6 #89 of 95 30 #67 of 95
Growth 99 #2 of 88 54 #41 of 88 58 #38 of 88
Profitability 71 #26 of 87 6 #82 of 87 33 #59 of 87
Financial Health 79 #22 of 100 99 #2 of 100 69 #32 of 100
Shareholder Returns 56 #26 of 58 – 19 #47 of 58
Overall 65 41 42
  • CAI ranked among 102 companies in Healthcare Providers
  • GRAL ranked among 102 companies in Healthcare Providers
  • NEO ranked among 102 companies in Healthcare Providers

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodCAIGRALNEOSPY
1 month +9.3%-6.8%-10.4% -1.0%
3 months +101.9%+93.7%+9.0% -0.4%
6 months +73.7%+128.9%+92.9% +4.5%
Year to date +23.1%+67.8%+45.8% +12.4%
1 year +6.5%+78.0%+69.8% +13.6%
3 years ——+12.3% +76.4%
3 years, per year ——+3.9% +20.8%
5 years ——-58.6% +63.7%
5 years, per year ——-16.2% +10.4%
10 years ——+114.1% +267.7%
10 years, per year ——+7.9% +13.9%

Risk

MeasureCAIGRALNEOSPY
Volatility, 1Y 69.8%111.5%53.7% 12.8%
Downside volatility, 1Y 70.3%126.9%53.0% 12.7%
Beta vs S&P 500, 1Y 1.552.771.10 1.00
Return / volatility, 1Y 0.090.701.30 1.06
Max drawdown, 5Y -63.0%-62.9%-88.9% -25.4%
From 52-week high -8.1%-9.6%-13.9% -1.6%
52-week high $36.14$158.92$19.91 $779.14
52-week low $14.55$43.03$7.19 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleCAIGRALNEO
P/E now vs peer median 98.2xmedian 25.6x -15.8xmedian 25.6x -68.3xmedian 25.6x
P/S now vs peer median 9.1xmedian 1.6x 40.8xmedian 1.6x 2.8xmedian 1.6x
EV/EBITDA now vs peer median 55.0xmedian 16.0x -13.7xmedian 16.0x 124.4xmedian 16.0x
P/FCF now vs peer median 329.5xmedian 21.6x -21.7xmedian 21.6x -77.5xmedian 21.6x
P/B now vs peer median 14.9xmedian 3.4x 2.5xmedian 3.4x 2.8xmedian 3.4x
PEG now vs peer median —median 0.74 —median 0.74 -2.20median 0.74

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsCAIGRALNEO
Revenue $1.05B $157.21M $787.75M
Gross profit $724.14M $75.51M $352.67M
Operating income $139.94M -$559.25M -$49.37M
Net income $96.06M -$391.59M -$32.30M
Free cash flow $28.91M -$296.16M -$28.58M
R&D $129.36M $190.72M $39.33M
EPS (diluted) $0.33 $-9.08 $-0.25
Cash & equivalents $665.32M $55.65M $139.28M
Total debt $393.27M – –
Shares (diluted) 295.14M 43.11M 128.59M
Enterprise value $6.34B $3.29B $1.62B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricCAIGRALNEO
P/E 98.2x -15.8x -68.3x
P/FCF 329.5x -21.7x -77.5x
P/Operating cash flow 113.5x -21.8x 517.3x
P/S 9.1x 40.8x 2.8x
P/B 14.9x 2.5x 2.8x
P/Tangible book 14.9x 8.4x 4.1x
EV/EBITDA 55.0x -13.7x 124.4x
EV/EBIT 65.4x -9.9x -42.0x
EV/Revenue 8.7x 35.3x 2.6x
EV/FCF 316.5x -18.8x -72.6x
EV/Operating cash flow 109.1x -18.8x 484.8x
PEG (3Y EPS CAGR) – – -2.20

Growth

14 metrics
MetricCAIGRALNEO
Revenue growth (1Y) 61.5% 17.1% 11.1%
Revenue CAGR (3Y) – – 11.1%
Gross profit growth (1Y) 86.2% 30.2% 14.4%
Gross profit CAGR (3Y) – – 14.7%
Operating income growth (1Y) 274.2% 11.6% 59.2%
Operating income CAGR (3Y) – – 24.7%
Net income growth (1Y) 151.4% 11.6% 71.5%
Net income CAGR (3Y) – – 30.5%
EPS growth (1Y) 114.2% 26.6% 71.6%
EPS CAGR (3Y) – – 31.1%
Operating cash flow growth (1Y) 15,464% 20.3% -68.7%
Operating cash flow CAGR (3Y) – – 29.7%
Free cash flow growth (1Y) 306.4% 20.3% -67.7%
Free cash flow CAGR (3Y) – – 16.8%

Profitability

14 metrics
MetricCAIGRALNEO
Gross margin 69.1% 48.0% 44.8%
EBITDA margin 15.9% -257.6% 2.1%
Operating margin 13.4% -355.7% -6.3%
Pretax margin 9.3% -336.8% -4.6%
Net margin 9.2% -249.1% -4.1%
FCF margin 2.8% -188.4% -3.6%
Operating cash flow margin 8.0% -187.5% 0.5%
Return on equity 15.6% -15.5% -4.1%
Return on assets 7.7% -13.9% -2.4%
Return on invested capital 13.7% – –
Return on capital employed 12.9% -20.4% -4.0%
Asset turnover 0.8x 0.1x 0.6x
Cash conversion (OCF / net income) 0.9x 0.8x -0.1x
Stock comp / revenue 6.7% 40.9% 4.4%

Financial Health

11 metrics
MetricCAIGRALNEO
Debt / assets 31.3% – –
Debt / equity 0.6x – –
Net debt / EBITDA -2.3x – –
Debt / FCF 13.6x – –
Liabilities / assets 49.1% 10.6% 41.9%
Equity / assets 50.9% 89.4% 58.1%
Interest coverage 3.3x – -15.2x
Current ratio 6.7x 10.9x 3.5x
Quick ratio 5.7x 10.6x 3.0x
Cash ratio 4.8x 10.3x 1.2x
Altman Z-score 8.52 7.42 2.55

Shareholder Returns

7 metrics
MetricCAIGRALNEO
Dividend yield – – –
Net buyback yield 0.0% – -0.7%
Shareholder yield 0.0% – -0.7%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusCAIGRALNEO
Forward P/E 302.0xFY2026 – 85.7xFY2026
EPS, next fiscal year $0.11FY2026 $-9.05FY2026 $0.20FY2026
EPS growth, next FY – – +66.7%FY2026
EPS growth, the year after +236.4% – +80.0%
Revenue, next fiscal year $1.06BFY2026 $169.78MFY2026 $778.61MFY2026
Revenue growth, next FY +30.1%FY2026 +15.4%FY2026 +7.1%FY2026
Revenue growth, the year after +21.6% +38.2% +6.5%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersCAIGRALNEO
Held by institutions 52.0% 85.4% 100.0%
Institutions holding 246 374 266
Change in shares held, QoQ -6.3% +8.4% +8.1%
Institutions buying 175 183 156
Institutions selling 47 101 62
Buyers to sellers 3.72 1.81 2.52

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

CAIGRALNEO
CAI 1.00 0.36 0.45
GRAL 0.36 1.00 0.32
NEO 0.45 0.32 1.00

Add a Peer

Largest companies in the same industry

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Frequently Asked Questions

Which is bigger, CAI, GRAL and NEO?

Caris Life Sciences (CAI) is the largest by market capitalisation: Caris Life Sciences (CAI) $9.52B, Grail (GRAL) $6.42B, Neogenomics (NEO) $2.21B.

Which company is growing faster?

Caris Life Sciences (CAI) grew revenue fastest over the trailing twelve months: Caris Life Sciences (CAI) +61.5%, Grail (GRAL) +17.1%, Neogenomics (NEO) +11.1%.

Which company is more profitable?

Caris Life Sciences (CAI) has the highest net margin (Caris Life Sciences (CAI) 9.2%, Grail (GRAL) -249.1%, Neogenomics (NEO) -4.1%).

Which stock has performed better?

Over the past year Grail (GRAL) returned the most: Caris Life Sciences (CAI) +6.5%, Grail (GRAL) +78.0%, Neogenomics (NEO) +69.8%. Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Neogenomics (NEO) has been the steadiest (Caris Life Sciences (CAI) 69.8%, Grail (GRAL) 111.5%, Neogenomics (NEO) 53.7%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, CAI, GRAL and NEO?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Caris Life Sciences (CAI) leads on 4. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.