ALNY vs NXTS vs REGN Stock Comparison

Alnylam Pharmaceuticals, Nexentis Technologies and Regeneron Pharmaceuticals Prices as of Oct 27, 2026 Peers: Industry group

Head to Head

10 decided of 12

Regeneron Pharmaceuticals leads on 7 of the 12 questions below (Regeneron Pharmaceuticals 7, Alnylam Pharmaceuticals 3). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionALNYNXTSREGNLeader
Larger companyMarket capitalisation $30.66B $474.99K $83.74B REGN
Cheaper on earningsLower P/E, profitable companies only 41.8x 0.0x 19.3x REGN
Cheaper on forward earningsLower price / next fiscal year consensus EPS 33.5x — 14.3x REGN
Faster revenue growthRevenue growth, trailing twelve months +90.1% — +9.3% ALNY
More profitableNet margin, trailing twelve months 15.3% — 27.9% REGN
Better return on capitalReturn on invested capital — — 9.6% –
Less leveragedLower net debt / EBITDA — 1.6x -1.4x REGN
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months -52.6% -97.8% +39.4% REGN
Better 5-year returnAnnualised price return, 5 years +6.9%/yr -86.1%/yr +5.5%/yr ALNY
Less volatileAnnualised volatility, 1 year 51.2% 168.9% 32.8% REGN
Higher overall scoreMean of the five percentile scores vs peers 77/100 32/100 72/100 ALNY

Percentile Scorecard

ALNYNXTSREGN

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisALNYNXTSREGN
Valuation 81 #118 of 625 – 89 #71 of 625
Growth 98 #13 of 602 13 #523 of 602 42 #351 of 602
Profitability 93 #41 of 551 40 #329 of 551 90 #54 of 551
Financial Health 45 #359 of 656 43 #372 of 656 74 #172 of 656
Shareholder Returns 67 #121 of 365 – 65 #129 of 365
Overall 77 32 72
  • ALNY ranked among 672 companies in Pharmaceuticals and Biotechnology
  • NXTS ranked among 672 companies in Pharmaceuticals and Biotechnology
  • REGN ranked among 672 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodALNYNXTSREGNSPY
1 month -11.4%-60.5%+3.6% -0.2%
3 months -21.4%-62.6%+17.4% +3.9%
6 months -24.9%-87.8%+11.5% +8.2%
Year to date -43.0%-95.1%+5.7% +12.9%
1 year -52.6%-97.8%+39.4% +12.3%
3 years +49.4%-99.9%+5.3% +87.4%
3 years, per year +14.3%-89.5%+1.7% +23.3%
5 years +39.9%-100.0%+30.5% +67.9%
5 years, per year +6.9%-86.1%+5.5% +10.9%
10 years +526.3%-100.0%+123.4% +261.1%
10 years, per year +20.1%-66.5%+8.4% +13.7%

Risk

MeasureALNYNXTSREGNSPY
Volatility, 1Y 51.2%168.9%32.8% 12.7%
Downside volatility, 1Y 62.6%153.3%30.0% 12.7%
Beta vs S&P 500, 1Y 0.342.330.47 1.00
Return / volatility, 1Y -1.03-0.581.20 0.97
Max drawdown, 5Y -58.2%-100.0%-59.8% -25.4%
From 52-week high -52.9%-97.8%-4.2% -1.2%
52-week high $481.59$26.04$852.03 $779.14
52-week low $205.48$0.53$585.31 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleALNYNXTSREGN
P/E now vs peer median 41.3xmedian 17.2x 0.0xmedian 17.2x 19.4xmedian 17.2x
P/S now vs peer median 6.3xmedian 9.0x —median 9.0x 5.4xmedian 9.0x
EV/EBITDA now vs peer median 25.6xmedian 16.3x 1.5xmedian 16.3x 17.8xmedian 16.3x
P/FCF now vs peer median 37.0xmedian 18.7x —median 18.7x 22.3xmedian 18.7x
P/B now vs peer median 22.4xmedian 2.2x 0.2xmedian 2.2x 2.6xmedian 2.2x
PEG now vs peer median 1.09median 0.33 0.00median 0.33 7.29median 0.33

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsALNYNXTSREGN
Revenue $4.80B – $15.53B
Gross profit $3.83B – $13.18B
Operating income $999.78M -$5.28M $3.84B
Net income $733.11M -$14.06M $4.33B
Free cash flow $819.87M – $3.76B
R&D $1.51B $532.00K $6.28B
EPS (diluted) $5.30 $-17.10 $40.84
Cash & equivalents $1.71B $7.62M $2.46B
Total debt – $3.22M $1.99B
Shares (diluted) 138.28M 816.14K 106.00M
Enterprise value $18.71B -$22.17M $49.94B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricALNYNXTSREGN
P/E 41.3x 0.0x 19.4x
P/FCF 37.0x – 22.3x
P/Operating cash flow 33.3x – 17.9x
P/S 6.3x – 5.4x
P/B 22.4x 0.2x 2.6x
P/Tangible book 22.4x -0.2x 2.8x
EV/EBITDA 25.6x 1.5x 17.8x
EV/EBIT 27.0x 1.5x 20.3x
EV/Revenue 5.6x – 5.0x
EV/FCF 33.0x – 20.7x
EV/Operating cash flow 29.6x – 16.6x
PEG (3Y EPS CAGR) 1.09 0.00 7.29

Growth

14 metrics
MetricALNYNXTSREGN
Revenue growth (1Y) 90.1% – 9.3%
Revenue CAGR (3Y) 57.2% – 7.0%
Gross profit growth (1Y) 79.7% – 8.4%
Gross profit CAGR (3Y) 54.6% – 6.4%
Operating income growth (1Y) 654.9% -7.7% 0.1%
Operating income CAGR (3Y) 47.5% 3.0% -3.9%
Net income growth (1Y) 356.5% -48.2% -2.9%
Net income CAGR (3Y) 39.1% -35.8% 0.2%
EPS growth (1Y) 342.3% -567.8% -0.5%
EPS CAGR (3Y) 37.9% -45.2% 2.7%
Operating cash flow growth (1Y) 2,299% – -1.3%
Operating cash flow CAGR (3Y) 57.8% – -0.4%
Free cash flow growth (1Y) 1,151% – -2.4%
Free cash flow CAGR (3Y) 52.1% – -3.3%

Profitability

14 metrics
MetricALNYNXTSREGN
Gross margin 79.8% – 84.9%
EBITDA margin 22.0% – 28.1%
Operating margin 20.8% – 24.7%
Pretax margin 16.0% – 33.3%
Net margin 15.3% – 27.9%
FCF margin 17.1% – 24.2%
Operating cash flow margin 19.0% – 30.1%
Return on equity 63.8% -157.0% 13.7%
Return on assets 14.5% -71.9% 10.5%
Return on invested capital – – 9.6%
Return on capital employed 26.1% -31.5% 10.7%
Asset turnover 0.9x – 0.4x
Cash conversion (OCF / net income) 1.2x – 1.1x
Stock comp / revenue 7.0% – 6.4%

Financial Health

11 metrics
MetricALNYNXTSREGN
Debt / assets – 2.3% 4.8%
Debt / equity – 0.2x 0.1x
Net debt / EBITDA – 1.6x -1.4x
Debt / FCF – – 0.5x
Liabilities / assets 75.6% 89.8% 24.0%
Equity / assets 24.4% 10.2% 76.0%
Interest coverage 3.8x – 69.4x
Current ratio 3.1x 3.7x 3.3x
Quick ratio 2.8x 3.2x 2.6x
Cash ratio 2.2x 3.2x 1.4x
Altman Z-score 4.86 – 7.33

Shareholder Returns

7 metrics
MetricALNYNXTSREGN
Dividend yield – – 0.5%
Net buyback yield -0.5% – 3.0%
Shareholder yield -0.5% – 3.5%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusALNYNXTSREGN
Forward P/E 33.5xFY2026 – 14.3xFY2026
EPS, next fiscal year $6.76FY2026 – $57.08FY2026
EPS growth, next FY +190.1%FY2026 – +28.8%FY2026
EPS growth, the year after +34.3% – +15.5%
Revenue, next fiscal year $5.68BFY2026 – $17.05BFY2026
Revenue growth, next FY +53.1%FY2026 – +18.9%FY2026
Revenue growth, the year after +27.8% – +13.0%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersALNYNXTSREGN
Held by institutions 99.7% – 66.2%
Institutions holding 786 – 1,325
Change in shares held, QoQ +3.8% – +3.8%
Institutions buying 412 – 604
Institutions selling 277 – 534
Buyers to sellers 1.49 – 1.13

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

ALNYNXTSREGN
ALNY 1.00 0.03 0.14
NXTS 0.03 1.00 0.01
REGN 0.14 0.01 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, ALNY, NXTS and REGN?

Regeneron Pharmaceuticals (REGN) is the largest by market capitalisation: Alnylam Pharmaceuticals (ALNY) $30.66B, Nexentis Technologies (NXTS) $474.99K, Regeneron Pharmaceuticals (REGN) $83.74B.

Which stock is cheaper, ALNY, NXTS and REGN?

Regeneron Pharmaceuticals (REGN) trades on the lowest price-to-earnings ratio (Alnylam Pharmaceuticals (ALNY) 41.8x, Nexentis Technologies (NXTS) 0.0x, Regeneron Pharmaceuticals (REGN) 19.3x). On next year's consensus earnings, Regeneron Pharmaceuticals (REGN) is cheapest (Alnylam Pharmaceuticals (ALNY) 33.5x, Regeneron Pharmaceuticals (REGN) 14.3x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Alnylam Pharmaceuticals (ALNY) grew revenue fastest over the trailing twelve months: Alnylam Pharmaceuticals (ALNY) +90.1%, Regeneron Pharmaceuticals (REGN) +9.3%.

Which company is more profitable?

Regeneron Pharmaceuticals (REGN) has the highest net margin (Alnylam Pharmaceuticals (ALNY) 15.3%, Regeneron Pharmaceuticals (REGN) 27.9%).

Which stock has performed better?

Over the past year Regeneron Pharmaceuticals (REGN) returned the most: Alnylam Pharmaceuticals (ALNY) -52.6%, Nexentis Technologies (NXTS) -97.8%, Regeneron Pharmaceuticals (REGN) +39.4%. Over five years, Alnylam Pharmaceuticals (ALNY) compounded fastest (Alnylam Pharmaceuticals (ALNY) +6.9%/yr, Nexentis Technologies (NXTS) -86.1%/yr, Regeneron Pharmaceuticals (REGN) +5.5%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Regeneron Pharmaceuticals (REGN) has been the steadiest (Alnylam Pharmaceuticals (ALNY) 51.2%, Nexentis Technologies (NXTS) 168.9%, Regeneron Pharmaceuticals (REGN) 32.8%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, ALNY, NXTS and REGN?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Regeneron Pharmaceuticals (REGN) leads on 7. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.