Tango Therapeutics, Inc. (TNGX) Institutional Ownership

Ownership Summary

According to SEC filings for the period ending September 2025, Tango Therapeutics, Inc. (NASDAQ:TNGX) is held by 142 institutional firms.

• Tango Therapeutics saw its institutional ownership percentage rose to 125.9% in September 2025 from 117.6% in June 2025.
• The company experienced a 7.59% quarterly change in institutional shares held, alongside an increase of 17.36% in total owners annually.
• During the quarter, 74 institutions bought more Tango Therapeutics shares, 46 sold shares, and 22 of the 142 total investors held their position steady.
• Collectively, institutional investors increased their stake in Tango Therapeutics to 140.09Mn shares as of September 2025, a change that is up by 9.88Mn shares quarter on quarter and up 38.69Mn shares year over year.
• TRV GP IV, LLC's holding of 13.86Mn shares as of September 30, 2025 makes it the primary institutional investor in Tango Therapeutics, owning 12.46% of the stock.
• Among the most significant buyers of Tango Therapeutics during September 2025 were Paradigm Biocapital Advisors LP (3.09Mn), Siren, L.L.C. (2.52Mn), Point72 Asset Management, L.P. (2.47Mn), JANUS HENDERSON GROUP PLC (2.29Mn), STATE STREET CORP (1.98Mn).
• Leading sellers of Tango Therapeutics stock in September 2025 included ADAGE CAPITAL PARTNERS GP, L.L.C. (3.39Mn), TRV GP IV, LLC (3.00Mn), TCG Crossover Management, LLC (2.20Mn), Avoro Capital Advisors LLC (1.68Mn), Nantahala Capital Management, LLC (1.63Mn).
• The top 10 institutional holders of Tango Therapeutics for the quarter ending September 2025 included TRV GP IV, LLC (13.86Mn), FARALLON CAPITAL MANAGEMENT LLC (10.76Mn), EcoR1 Capital, LLC (10.63Mn), Boxer Capital Management, LLC (9.77Mn), TCG Crossover Management, LLC (8.54Mn), Woodline Partners LP (6.03Mn), Siren, L.L.C. (5.88Mn), BlackRock, Inc. (5.65Mn), Nextech Invest, Ltd. (5.53Mn), VANGUARD GROUP INC (5.05Mn).