As of September 29, 2026, Tango Therapeutics's top three insider holders are Rock Ventures Iv, L.P. Third (TenPercentOwner, 13.39Mn shares), Capital, Llc Ecor1 (TenPercentOwner, 10.63Mn shares), Capital, Llc Boxer (Other, 8.20Mn shares).
| # | Insider | Position | Direct | Indirect | Total | Share of Insiders | Last Filed |
|---|---|---|---|---|---|---|---|
| 1 | Rock Ventures Iv, L.P. Third | TenPercentOwner | 13,386,574 | 0 | 13,386,574 | 34.6% | 27 Oct, 2025 |
| 2 | Capital, Llc Ecor1 | TenPercentOwner | 0 | 10,630,736 | 10,630,736 | 27.5% | 08 Nov, 2024 |
| 3 | Capital, Llc Boxer | Other | 8,198,642 | 0 | 8,198,642 | 21.2% | 17 Oct, 2023 |
| 4 | Capital Management, Llc Boxer | Other | 0 | 3,610,642 | 3,610,642 | 9.3% | 07 Nov, 2024 |
| 5 | Barbara Weber | Director, Executive Chair | 1,629,254 | 0 | 1,629,254 | 4.2% | 04 Feb, 2026 |
| 6 | Malte Peters | President Ceo | 367,500 | 0 | 367,500 | 0.9% | 12 Jan, 2026 |
| 7 | Daniella Beckman | Chief Financial Officer | 184,297 | 0 | 184,297 | 0.5% | 04 Feb, 2026 |
| 8 | Alan Huang | Chief Scientific Officer | 167,584 | 0 | 167,584 | 0.4% | 02 Mar, 2023 |
| 9 | Adam Crystal | President, Rd | 115,743 | 0 | 115,743 | 0.3% | 03 Sep, 2026 |
| 10 | Investors, Llc Mva | Other | 108,793 | 0 | 108,793 | 0.3% | 02 Jul, 2024 |
| 11 | Douglas Barry | General Counsel | 66,014 | 0 | 66,014 | 0.2% | 06 Feb, 2025 |
| 12 | Jessica Newcomb | Principal Accounting Officer | 59,121 | 0 | 59,121 | 0.2% | 24 Sep, 2026 |
| 13 | Mace Rothenberg | Director | 41,500 | 0 | 41,500 | 0.1% | 08 Jun, 2026 |
| 14 | Matthew Gall | Chief Financial Officer | 40,000 | 0 | 40,000 | 0.1% | 05 May, 2026 |
| 15 | John B Ketchum | Director | 24,937 | 0 | 24,937 | 0.1% | 08 Jun, 2026 |
| 16 | Sung Lee | Director | 22,870 | 0 | 22,870 | 0.1% | 08 Jun, 2026 |
| 17 | Alexis Borisy | Director | 17,500 | 0 | 17,500 | 0.0% | 09 Jun, 2025 |
| 18 | Lesley Ann Calhoun | Director | 16,500 | 0 | 16,500 | 0.0% | 08 Jun, 2026 |
| 19 | Robert Azelby | Director | 5,740 | 0 | 5,740 | 0.0% | 23 Jun, 2026 |
| 20 | Reid M Huber | Director | 5,000 | 0 | 5,000 | 0.0% | 08 Jun, 2023 |
| 21 | Aaron I. Davis | Director | 5,000 | 0 | 5,000 | 0.0% | 08 Jun, 2023 |
Each row is that insider’s most recently reported position, from Form 4 filings over the last 60 months — which is why this total does not tie to the quarterly series above, where a quarter counts only the insiders who filed in it. Shares held through a fund or institutional portfolio are counted on the institutional ownership page instead.
| Date | Insider | Position | Transaction | Shares | Price | Value | Shares Held After | Ownership |
|---|---|---|---|---|---|---|---|---|
| 22 Sep, 2026 | Jessica Newcomb | Principal Accounting Officer | Disposed S | 700 | $22.80 | $15.96K | 66,621 | Direct |
| 22 Sep, 2026 | Jessica Newcomb | Principal Accounting Officer | Disposed S | 5,100 | $23.97 | $122.24K | 61,521 | Direct |
| 22 Sep, 2026 | Jessica Newcomb | Principal Accounting Officer | Disposed S | 2,400 | $25.17 | $60.41K | 59,121 | Direct |
| 01 Sep, 2026 | Adam Crystal | President, Rd | Acquired M | 27,000 | $5.20 | $140.40K | 142,743 | Direct |
| 01 Sep, 2026 | Adam Crystal | President, Rd | Disposed S | 27,000 | $22.37 | $603.91K | 115,743 | Direct |
| 01 Sep, 2026 | Adam Crystal | President, Rd | Disposed M | 27,000 | $0.00 | $0 | 260,040 | Direct |
| 03 Aug, 2026 | Adam Crystal | President, Rd | Acquired M | 27,000 | $5.20 | $140.40K | 142,743 | Direct |
| 03 Aug, 2026 | Adam Crystal | President, Rd | Disposed S | 5,267 | $26.79 | $141.10K | 137,476 | Direct |
| 03 Aug, 2026 | Adam Crystal | President, Rd | Disposed S | 21,733 | $27.35 | $594.42K | 115,743 | Direct |
| 03 Aug, 2026 | Adam Crystal | President, Rd | Disposed M | 27,000 | $0.00 | $0 | 287,040 | Direct |
| 01 Jul, 2026 | Adam Crystal | President, Rd | Acquired M | 27,000 | $5.20 | $140.40K | 142,743 | Direct |
| 01 Jul, 2026 | Adam Crystal | President, Rd | Disposed S | 19,629 | $29.34 | $575.96K | 123,114 | Direct |
| 01 Jul, 2026 | Adam Crystal | President, Rd | Disposed S | 7,371 | $30.25 | $222.95K | 115,743 | Direct |
| 01 Jul, 2026 | Adam Crystal | President, Rd | Disposed M | 27,000 | $0.00 | $0 | 314,040 | Direct |
| 19 Jun, 2026 | Robert Azelby | Director | Acquired A | 5,740 | $0.00 | $0 | 5,740 | Direct |
| 19 Jun, 2026 | Robert Azelby | Director | Acquired A | 35,910 | $0.00 | $0 | 35,910 | Direct |
| 05 Jun, 2026 | Lesley Ann Calhoun | Director | Acquired A | 4,000 | $0.00 | $0 | 16,500 | Direct |
| 05 Jun, 2026 | Sung Lee | Director | Acquired A | 570 | $0.00 | $0 | 22,870 | Direct |
| 05 Jun, 2026 | Mace Rothenberg | Director | Acquired A | 4,000 | $0.00 | $0 | 41,500 | Direct |
| 05 Jun, 2026 | John B Ketchum | Director | Acquired A | 4,000 | $0.00 | $0 | 24,937 | Direct |