Spero Therapeutics SPRO Revenue Breakdown

NASDAQ SPRO
$1.20 +0.01 (+0.84%)
At close: Sep 29, 2026 · 4:00 PM EDT
Annual revenue breakdowns for Spero Therapeutics, fiscal 2017 to 2025, as reported in its filings.
Annual history

Spero Therapeutics Revenue by Product & Service

Years FY 2017–2025
Lines 2
FY 2025 Total $47.13M

Collaboration Revenue - Related Party was Spero Therapeutics’s largest product and service line in fiscal 2025, bringing in $47.03M of $47.13M (100%).

Spero Therapeutics revenue by product and service, fiscal 2017 to 2025
Product and Service FY 2017 FY 2022 FY 2023 FY 2024 FY 2025
Collaboration Revenue - Related Party — $95.80M — $47.03M
Spr206 — — — $100.00K
Total $19.00M $96.74M $371.00K $47.13M
Totals include 3 discontinued lines from earlier reporting.

Spero Therapeutics revenue by product and service: what the figures show

Spero Therapeutics brought in $47.13M from its two product and service lines in fiscal 2025, the year ended December 31, 2025. Spero Therapeutics regrouped these lines after fiscal 2024, so the total does not compare directly with that year's $371.00K. Collaboration Revenue - Related Party was the largest at $47.03M (99.8%), ahead of Spr206 at $100.00K (0.2%).

Spero Therapeutics began breaking out Collaboration Revenue - Related Party in fiscal 2023 and Spr206 in fiscal 2025. Spero Therapeutics stopped reporting Research & Development Services Related To Upcoming Milestones ($19.00M in fiscal 2022) and Collaboration Revenue ($371.00K in fiscal 2024) as separate lines.

Annual history

Spero Therapeutics Revenue by Research And Development Arrangement Contract To Perform For Others By Type

Years FY 2017
Lines 3
FY 2017 Total $2.00M

Carb-X was Spero Therapeutics’s largest revenue line in fiscal 2017, bringing in $900.00K of $2.00M (45%).

Spero Therapeutics revenue by research and development arrangement contract to perform for others by type, fiscal 2017 to 2017
Research And Development Arrangement Contract To Perform For Others By Type FY 2017 FY 2017
Carb-X — $900.00K
U.S. Department Of Defense — $700.00K
Niaid $100.00K $400.00K
Total $100.00K $2.00M

Spero Therapeutics revenue by research and development arrangement contract to perform for others by type: what the figures show

Spero Therapeutics brought in $2.00M from its three revenue lines in fiscal 2017, the year ended December 31, 2017. Spero Therapeutics regrouped these revenue lines after fiscal 2017, so the total does not compare directly with that year's $100.00K. Carb-X was the largest at $900.00K (45.0%), ahead of U.S. Department Of Defense at $700.00K (35.0%) and Niaid at $400.00K (20.0%).

Questions

Spero Therapeutics Revenue Breakdown FAQ

How does Spero Therapeutics make money?

Spero Therapeutics (SPRO) reports its revenue by product and service and by research and development arrangement contract to perform for others by type. In fiscal 2025, Collaboration Revenue - Related Party was its largest product and service line, bringing in $47.03M (99.8% of the total), followed by Spr206 at $100.00K (0.2%).

What is Spero Therapeutics' largest product and service line?

Collaboration Revenue - Related Party was Spero Therapeutics' largest product and service line in fiscal 2025, bringing in $47.03M, or 99.8% of the $47.13M total across its two product and service lines.

What is Spero Therapeutics' largest revenue line?

Carb-X was Spero Therapeutics' largest revenue line in fiscal 2017, bringing in $900.00K, or 45.0% of the $2.00M total across its three revenue lines.

Where does this revenue breakdown data come from?

Every figure comes from Spero Therapeutics' annual financial filings, as reported. Each line keeps the name Spero Therapeutics gives it, and years follow its fiscal calendar.

How far back does Spero Therapeutics' revenue breakdown go?

Spero Therapeutics' revenue by product and service goes back to fiscal 2017, with figures through fiscal 2025. The latest four fiscal years are free to view, and the full history is available with a Business Quant subscription.