Sera Prognostics, Inc. (SERA) Institutional Ownership

Ownership Summary

Sera Prognostics, Inc. (NASDAQ:SERA) has 56 institutional investors with active 13F positions as of December 2025.

• Collectively, these holders controlled 35.8% of Sera Prognostics's outstanding shares in December 2025, down from 36.7% in September 2025.
• Their total shares held in SERA increased 0.38% quarter over quarter, and separately, investors owning Sera Prognostics decreased 26.32% from a year ago.
• Of these 56 holders, 20 added to their stakes in Sera Prognostics, 15 trimmed positions, and 21 made no changes.
• Combined, these investors held 17.73Mn shares in SERA for December 2025, up by 67.47K shares quarter on quarter, and down 658.94K shares year over year.
• BAKER BROS. ADVISORS LP leads ownership in SERA with 5.5Mn shares as of December 31, 2025, equal to 11.1% of outstanding shares.
• The most significant purchases of SERA for the quarter ending December 2025 came from PSP Research LLC (2.4Mn), VANGUARD CAPITAL MANAGEMENT LLC (1.2Mn), SANDERS MORRIS HARRIS LLC (314.95K), Aberdeen Group plc (271.08K), VANGUARD FIDUCIARY TRUST CO (169.66K).
• Leading sellers of Sera Prognostics shares for the quarter ending December 2025 were CITADEL ADVISORS LLC (458.7K), Whetstone Capital Advisors, LLC (152.82K), Goldman Sachs Group Inc (38.73K), MILLENNIUM MANAGEMENT LLC (21.67K), JANE STREET GROUP, LLC (14.92K).
• Sera Prognostics's 10 largest shareholders as of December 2025 include BAKER BROS. ADVISORS LP (5.5Mn), Whetstone Capital Advisors, LLC (3.31Mn), Aberdeen Group plc (2.55Mn), PSP Research LLC (2.4Mn), Vivo Capital, LLC (1.65Mn), VANGUARD CAPITAL MANAGEMENT LLC (1.2Mn), CAPTRUST FINANCIAL ADVISORS (536.76K), GEODE CAPITAL MANAGEMENT, LLC (363.62K), SANDERS MORRIS HARRIS LLC (314.95K), CITADEL ADVISORS LLC (248.91K) per Business Quant data.