Sera Prognostics, Inc. (SERA) Institutional Ownership

Ownership Summary

Sera Prognostics, Inc. (NASDAQ:SERA) appears in 56 institutional 13F filings for the quarter ending December 2025.

• These investors collectively held 35.8% of Sera Prognostics's outstanding shares in December 2025, down from 36.7% in September 2025.
• Their total shares held in SERA increased 0.38% from the prior quarter, while the number of investors in Sera Prognostics decreased 26.32% year over year.
• During the quarter, 20 of these 56 funds increased positions in SERA, 15 reduced exposure, and 21 held steady.
• The aggregate institutional position in Sera Prognostics amounted to 17.73Mn shares as of December 2025, up by 67.47K shares quarter on quarter, and down 658.94K shares year over year.
• BAKER BROS. ADVISORS LP holds the largest position in SERA at 5.5Mn shares as of December 31, 2025, or 11.1% of shares outstanding.
• The largest buyers of Sera Prognostics for the quarter ending December 2025 were Corient Private Wealth LLC (100.0K), JANE STREET GROUP, LLC (68.83K), CITADEL ADVISORS LLC (53.87K), SUSQUEHANNA INTERNATIONAL GROUP, LLP (49.16K), GSA CAPITAL PARTNERS LLP (42.04K).
• The largest sales of SERA for the quarter ending December 2025 came from Whetstone Capital Advisors, LLC (172.66K), CAPTRUST FINANCIAL ADVISORS (65.57K), Squarepoint Ops LLC (56.74K), Barclays Plc (22.72K), MILLENNIUM MANAGEMENT LLC (14.11K).
• Per Business Quant, the top 10 investors in SERA for the quarter ending December 2025 include BAKER BROS. ADVISORS LP (5.5Mn), Whetstone Capital Advisors, LLC (3.46Mn), Aberdeen Group plc (2.28Mn), Vivo Capital, LLC (1.65Mn), VANGUARD GROUP INC (1.24Mn), CITADEL ADVISORS LLC (707.61K), CAPTRUST FINANCIAL ADVISORS (536.77K), GEODE CAPITAL MANAGEMENT, LLC (334.64K), AWM Investment Company, Inc. (207.38K), Corient Private Wealth LLC (200.0K).