Sera Prognostics, Inc. (SERA) Institutional Ownership

Ownership Summary

Sera Prognostics, Inc. (NASDAQ:SERA) has 56 institutional investors that have filed 13F reports for the period ending December 2025.

• Collectively, these holders controlled 35.8% of Sera Prognostics's outstanding shares in December 2025, down from 36.7% in September 2025.
• They increased total shares held in SERA by 0.38% quarter over quarter, and investors in Sera Prognostics decreased 26.32% from a year ago.
• Among the 56 funds, 20 bought more Sera Prognostics shares, 15 sold down, and 21 held their ground.
• Combined, these investors held 17.73Mn shares in SERA for December 2025, up by 67.47K shares quarter on quarter, and down 658.94K shares year over year.
• As of December 31, 2025, the biggest holder of Sera Prognostics is BAKER BROS. ADVISORS LP at 5.5Mn shares, representing 11.1% of shares outstanding.
• Leading buyers of Sera Prognostics shares for the quarter ending December 2025 were PSP Research LLC (2.4Mn), VANGUARD CAPITAL MANAGEMENT LLC (1.2Mn), SANDERS MORRIS HARRIS LLC (314.95K), Aberdeen Group plc (271.08K), VANGUARD FIDUCIARY TRUST CO (169.66K).
• Top sellers of SERA stock for the quarter ending December 2025 included CITADEL ADVISORS LLC (458.7K), Whetstone Capital Advisors, LLC (152.82K), Goldman Sachs Group Inc (38.73K), MILLENNIUM MANAGEMENT LLC (21.67K), JANE STREET GROUP, LLC (14.92K).
• Business Quant data shows the 10 biggest positions in Sera Prognostics as of December 2025 are held by BAKER BROS. ADVISORS LP (5.5Mn), Whetstone Capital Advisors, LLC (3.31Mn), Aberdeen Group plc (2.55Mn), PSP Research LLC (2.4Mn), Vivo Capital, LLC (1.65Mn), VANGUARD CAPITAL MANAGEMENT LLC (1.2Mn), CAPTRUST FINANCIAL ADVISORS (536.76K), GEODE CAPITAL MANAGEMENT, LLC (363.62K), SANDERS MORRIS HARRIS LLC (314.95K), CITADEL ADVISORS LLC (248.91K).