Opko Health, Inc. (OPK) Institutional Ownership

Ownership Summary

Opko Health, Inc. (NASDAQ:OPK) has 228 institutional investors that have filed 13F reports for the period ending March 2026.

• These investors collectively held 26.6% of Opko Health's outstanding shares in March 2026, down from 27.3% in December 2025.
• They increased total shares held in OPK by 18.29% quarter over quarter, and investors in Opko Health decreased 10.59% from a year ago.
• Among the 228 funds, 98 bought more Opko Health shares, 63 sold down, and 67 held their ground.
• Altogether, these fund groups held 201.95Mn shares in OPK by March 2026, up by 31.23Mn shares quarter on quarter, and down 53.79Mn shares year over year.
• As of March 31, 2026, Rubric Capital Management LP held the largest stake in Opko Health with 47.79Mn shares, accounting for 6.3% of total shares outstanding.
• Leading buyers of Opko Health shares for the quarter ending March 2026 were VANGUARD PORTFOLIO MANAGEMENT LLC (14.77Mn), VANGUARD CAPITAL MANAGEMENT LLC (14.5Mn), VANGUARD FIDUCIARY TRUST CO (2.74Mn), OP Asset Management Ltd (2.2Mn), BlackRock, Inc. (1.38Mn).
• The largest sales of OPK for the quarter ending March 2026 came from Goldman Sachs Group Inc (4.3Mn), AQR CAPITAL MANAGEMENT LLC (1.26Mn), CITADEL ADVISORS LLC (777.89K), JANE STREET GROUP, LLC (660.96K), HRT FINANCIAL LP (584.72K).
• According to Business Quant data, leading holders of OPK for March 2026 are Rubric Capital Management LP (47.79Mn), BlackRock, Inc. (36.23Mn), VANGUARD PORTFOLIO MANAGEMENT LLC (14.77Mn), VANGUARD CAPITAL MANAGEMENT LLC (14.5Mn), GEODE CAPITAL MANAGEMENT, LLC (11.3Mn), State Street Corp (9.5Mn), Goldman Sachs Group Inc (7.68Mn), UBS Group AG (6.07Mn), Whitefort Capital Management, LP (4.25Mn), Northern Trust Corp (3.62Mn).