Opko Health, Inc. (OPK) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

779,919,259Shares Outstanding

205,276,642Shares held by institutions

$224,777,923Value of institutional holdings

26.32%Institutional ownership %

4.37%Shares Changed QoQ

215No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Opko Health, Inc. (NASDAQ:OPK) is held by 213 institutional investors per 13F filings through December 2025.

Their combined ownership stood at 25.5% of outstanding shares in December 2025, up from 25.5% in September 2025.
They increased total shares held in OPK by 1.88% quarter over quarter, and investors in Opko Health decreased 6.99% from a year ago.
During the quarter, 72 of these 213 funds increased positions in OPK, 76 reduced exposure, and 65 held steady.
Combined, these investors held 199.17Mn shares in OPK for December 2025, up by 3.68Mn shares quarter on quarter, and down 4.22Mn shares year over year.
As of December 31, 2025, the biggest holder of Opko Health is OP Asset Management Ltd at 2.2Mn shares, representing 0.28% of shares outstanding.
Top purchasers of OPK stock for the quarter ending December 2025 included OP Asset Management Ltd (2.2Mn), U.S. Capital Wealth Advisors, LLC (133.26K), WEALTH ENHANCEMENT ADVISORY SERVICES, LLC (62.36K), SG Americas Securities, LLC (33.82K), Apella Capital, LLC (27.02K).
The largest sellers of Opko Health for the quarter ending December 2025 were Sterling Capital Management LLC (10.0K), Key FInancial Inc (2.0K), Formidable Asset Management, LLC (1.0K), True Wealth Design, LLC (313), Diversified Trust Co (252).
According to Business Quant data, leading holders of OPK for December 2025 are OP Asset Management Ltd (2.2Mn), WASHINGTON GROWTH STRATEGIES LLC (1.36Mn), Assenagon Asset Management S.A. (652.07K), U.S. Capital Wealth Advisors, LLC (133.26K), HIGHLINE WEALTH PARTNERS LLC (116.68K), SG Americas Securities, LLC (87.85K), Pictet Asset Management Holding SA (65.5K), WEALTH ENHANCEMENT ADVISORY SERVICES, LLC (62.36K), KESTRA PRIVATE WEALTH SERVICES, LLC (58.45K), STRS OHIO (31.9K).

219 Institutional Holders

205,276,642 Total Shares Held

Rows:

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Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
Rubric Capital Management LP	31 Dec, 2025	47,791,243	0	0.00%	$60,216,966.00
BlackRock, Inc.	31 Dec, 2025	34,852,030	1,679,646	5.06%	$43,913,559.00
VANGUARD GROUP INC	31 Dec, 2025	32,457,788	-5,078,109	-13.53%	$40,896,813.00
Goldman Sachs Group Inc	31 Dec, 2025	11,973,826	9,587,291	401.72%	$15,087,022.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	11,061,318	67,973	0.62%	$13,939,903.00
State Street Corp	31 Dec, 2025	8,951,762	-46,178	-0.51%	$11,279,220.00
UBS Group AG	31 Dec, 2025	5,352,784	577,248	12.09%	$6,744,509.00
Whitefort Capital Management, LP	31 Dec, 2025	4,253,340	-646,660	-13.20%	$5,359,208.00
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	31 Dec, 2025	3,692,650	-76,284	-2.02%	$4,652,739.00
Northern Trust Corp	31 Dec, 2025	3,438,312	-219,534	-6.00%	$4,332,273.00
CITADEL ADVISORS LLC	31 Dec, 2025	2,857,433	2,577,558	920.97%	$3,600,366.00
AWM Investment Company, Inc.	31 Dec, 2025	2,100,000	-100,000	-4.55%	$2,646,000.00
AQR CAPITAL MANAGEMENT LLC	31 Dec, 2025	2,026,957	-846,459	-29.46%	$2,553,965.00
JANE STREET GROUP, LLC	31 Dec, 2025	1,775,336	1,512,498	575.45%	$2,236,923.00
DIMENSIONAL FUND ADVISORS LP	31 Dec, 2025	1,611,318	-56,050	-3.36%	$2,031,403.00
WASHINGTON GROWTH STRATEGIES LLC	31 Dec, 2025	1,356,124	0	0.00%	$1,708,717.00
PFG Investments, LLC	31 Dec, 2025	1,320,391	-16,984	-1.27%	$1,663,693.00
Bank of New York Mellon Corp	31 Dec, 2025	1,310,094	33,226	2.60%	$1,650,718.00
Y.D. More Investments Ltd	31 Dec, 2025	1,306,452	-192,666	-12.85%	$1,670,948.00
VOYA INVESTMENT MANAGEMENT LLC	31 Dec, 2025	1,102,174	-115,828	-9.51%	$1,388,739.00

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