Opko Health, Inc. (OPK) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

0Shares Outstanding

5,332,909Shares held by institutions

$5,892,864Value of institutional holdings

26.32%Institutional ownership %

-4.16%Shares Changed QoQ

216No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Opko Health, Inc. (NASDAQ:OPK) is held by 213 institutional investors per 13F filings through December 2025.

Collectively, these holders controlled 25.5% of Opko Health's outstanding shares in December 2025, up from 25.5% in September 2025.
They increased total shares held in OPK by 1.88% quarter over quarter, and investors in Opko Health decreased 6.99% from a year ago.
Of these 213 funds, 72 grew their exposure to Opko Health, 76 cut back, and 65 maintained positions.
The aggregate institutional position in Opko Health amounted to 199.17Mn shares as of December 2025, up by 3.68Mn shares quarter on quarter, and down 4.22Mn shares year over year.
As of December 31, 2025, the biggest holder of Opko Health is Rubric Capital Management LP at 47.79Mn shares, representing 6.13% of shares outstanding.
Top purchasers of OPK stock for the quarter ending December 2025 included Goldman Sachs Group Inc (3.6Mn), CITADEL ADVISORS LLC (2.58Mn), BlackRock, Inc. (1.68Mn), JANE STREET GROUP, LLC (1.51Mn), Clearstead Advisors, LLC (882.37K).
The largest sales of OPK for the quarter ending December 2025 came from VANGUARD GROUP INC (5.08Mn), Bank Of America Corp /De/ (2.01Mn), AQR CAPITAL MANAGEMENT LLC (846.46K), Whitefort Capital Management, LP (646.66K), TWO SIGMA INVESTMENTS, LP (520.9K).
Per Business Quant, the top 10 investors in OPK for the quarter ending December 2025 include Rubric Capital Management LP (47.79Mn), BlackRock, Inc. (34.85Mn), VANGUARD GROUP INC (32.46Mn), GEODE CAPITAL MANAGEMENT, LLC (11.06Mn), State Street Corp (8.95Mn), Goldman Sachs Group Inc (5.99Mn), UBS Group AG (5.35Mn), Whitefort Capital Management, LP (4.25Mn), CHARLES SCHWAB INVESTMENT MANAGEMENT INC (3.69Mn), Northern Trust Corp (3.44Mn).

214 Institutional Holders

5,332,909 Total Shares Held

Rows:

Download Data

Owner Name	Date	Change (QoQ)	Change (%)	Value (USD)
BlackRock, Inc.	31 Dec, 2025	1,679,646	5.06%	$0.00
VANGUARD GROUP INC	31 Dec, 2025	-5,078,109	-13.53%	$0.00
Rubric Capital Management LP	31 Dec, 2025	0	0.00%	$0.00
Barclays Plc	31 Dec, 2025	-467,853	-41.36%	$0.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	67,973	0.62%	$0.00
UBS Group AG	31 Dec, 2025	577,248	12.09%	$0.00
World Investment Advisors	31 Dec, 2025	92,422	227.54%	$0.00
State Street Corp	31 Dec, 2025	-46,178	-0.51%	$0.00
Whitefort Capital Management, LP	31 Dec, 2025	-646,660	-13.20%	$0.00
Farmers National Bank	31 Dec, 2025	0	0.00%	$0.00
Goldman Sachs Group Inc	31 Dec, 2025	3,600,378	150.86%	$0.00
WASHINGTON GROWTH STRATEGIES LLC	31 Dec, 2025	0	0.00%	$0.00
Rockefeller Capital Management L.P.	31 Dec, 2025	-599	-42.76%	$0.00
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	31 Dec, 2025	-76,284	-2.02%	$0.00
PFG Investments, LLC	31 Dec, 2025	-16,984	-1.27%	$0.00
Northern Trust Corp	31 Dec, 2025	-219,534	-6.00%	$0.00
Y.D. More Investments Ltd	31 Dec, 2025	-192,666	-12.85%	$0.00
CITADEL ADVISORS LLC	31 Dec, 2025	2,577,558	920.97%	$0.00
Tejara Capital Ltd	31 Dec, 2025	0	0.00%	$0.00
AWM Investment Company, Inc.	31 Dec, 2025	-100,000	-4.55%	$0.00

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