Opko Health, Inc. (OPK) Insider Ownership

Historic Insider Ownership Trends

OPK's three largest insider shareholders as of June 06, 2026 are Phillip Md Et Al Frost (Ceo Chairman, 216.71Mn shares), Phillip Md Et Al Frost (Ceo Chairman, 203.97Mn shares), Gary J. Nabel (Chief Innovation Officer, 39.80Mn shares).

Top Direct Holders

Insider ownership data is derived from the last 60 months of Form 4 SEC filings.
Holder Position Shares (Direct) Shares (Indirect) Report Date
Phillip Md Et Al Frost Ceo Chairman 0 216,706,448 21 Nov, 2025
Jane Ph D Hsiao Vice Chairman Cto 28,499,880 0 26 Jul, 2024
Richard C Jr Pfenniger - 325,000 0 05 Jan, 2024
Richard M Krasno - 0 103,333 29 Jan, 2024
Alexis Borisy - 312,612 0 13 May, 2022
Adam Logal Sr. Vice President, Cfo 616,662 0 26 Jul, 2024
Steven D Rubin Executive Vp Administration 6,625,232 0 26 Jul, 2024
Elias A. Zerhouni Vice Chairman And President 0 39,555,028 22 Jun, 2022
Gary J. Nabel Chief Innovation Officer 0 39,795,028 24 Jun, 2022

* Please note that the shares above only reflect shares from the fund portfolio and the institutional portfolio. Shares from the personal portfolio are excluded from this Institutional Ownership Page. See these insiders' latest transactions here on Insider Page.

Recent Insider Transactions

Detailed insider trading activity based on Form 4 SEC filings.
Download Data
Transaction Date Insider Name Security Class Transaction Type Shares Traded Price Shares Remaining Ownership Code
18 Mar, 2026 Subbarao V Uppaluri Stock Option (Right to Buy) A 50,000 $0.00 50,000 D A
21 Nov, 2025 Phillip Md Et Al Frost Common Stock A 102,371 $1.30 216,228,819 I P
21 Nov, 2025 Phillip Md Et Al Frost Common Stock A 3,894 $1.32 216,232,713 I P
21 Nov, 2025 Phillip Md Et Al Frost Common Stock A 89,375 $1.33 216,322,088 I P
21 Nov, 2025 Phillip Md Et Al Frost Common Stock A 191,490 $1.33 216,513,578 I P
21 Nov, 2025 Phillip Md Et Al Frost Common Stock A 192,870 $1.34 216,706,448 I P
20 Nov, 2025 Phillip Md Et Al Frost Common Stock A 119,129 $1.32 215,665,577 I P
20 Nov, 2025 Phillip Md Et Al Frost Common Stock A 47,105 $1.33 215,712,682 I P
20 Nov, 2025 Phillip Md Et Al Frost Common Stock A 211,948 $1.33 215,924,630 I P
20 Nov, 2025 Phillip Md Et Al Frost Common Stock A 161,818 $1.34 216,086,448 I P
20 Nov, 2025 Phillip Md Et Al Frost Common Stock A 24,579 $1.34 216,111,027 I P
20 Nov, 2025 Phillip Md Et Al Frost Common Stock A 1,757 $1.35 216,112,784 I P
20 Nov, 2025 Phillip Md Et Al Frost Common Stock A 13,664 $1.35 216,126,448 I P
19 Nov, 2025 Phillip Md Et Al Frost Common Stock A 36,325 $1.28 215,002,773 I P
19 Nov, 2025 Phillip Md Et Al Frost Common Stock A 58,160 $1.29 215,060,933 I P
19 Nov, 2025 Phillip Md Et Al Frost Common Stock A 300 $1.29 215,061,233 I P
19 Nov, 2025 Phillip Md Et Al Frost Common Stock A 21,236 $1.30 215,082,469 I P
19 Nov, 2025 Phillip Md Et Al Frost Common Stock A 30,082 $1.30 215,112,551 I P
19 Nov, 2025 Phillip Md Et Al Frost Common Stock A 12,993 $1.31 215,125,544 I P
19 Nov, 2025 Phillip Md Et Al Frost Common Stock A 66,504 $1.31 215,192,048 I P