Nautilus Biotechnology NAUT Institutional Ownership

Updated Oct 11, 2026

Nautilus Biotechnology, Inc. (NASDAQ:NAUT) was reported as a holding by 93 institutional investors in 13F filings for the quarter ended June 30, 2026.

• These investors held 39.44% of outstanding shares in Q2 2026, down from 42.91% the quarter before.
• Total holdings of NAUT shares fell 7.72% from Q1 2026, and the holder count rose 38.81% from Q2 2025.
• Among the 93 holders of Nautilus Biotechnology, 59 added to their positions, 12 reduced their stakes and 22 left their positions unchanged.
• Altogether, institutional holders owned 50.14Mn NAUT shares at the end of Q2 2026, down 4.2Mn from the prior quarter and down 8.65Mn from a year earlier.
• Perceptive Advisors LLC held the largest position in NAUT at 11.63Mn shares as of June 30, 2026, or 9.15% of shares outstanding.
• Among holders that already owned Nautilus Biotechnology, the biggest buyers in Q2 2026 were BlackRock, Inc. (+2.5Mn shares), Geode Capital Management, LLC (+662.01K shares), Barclays PLC (+652K shares), Renaissance Technologies LLC (+424.81K shares) and State Street Corp (+343.24K shares).
• On the other side, among holders that kept a position in Nautilus Biotechnology, the largest reductions in Q2 2026 came from a16z Capital Management, L.L.C. (-8.59Mn shares), Clearstead Advisors, LLC (-1.44Mn shares), Millennium Management LLC (-1.08Mn shares), Perceptive Advisors LLC (-960K shares) and Goldman Sachs Group Inc (-138.02K shares).
• Per Business Quant, the top 10 investors in NAUT for the quarter ended June 30, 2026 were Perceptive Advisors LLC (11.63Mn shares), a16z Capital Management, L.L.C. (9.06Mn shares), Cercano Management LLC (7.17Mn shares), BlackRock, Inc. (2.69Mn shares), Vanguard Capital Management LLC (2.55Mn shares), Comprehensive Financial Management LLC (2.21Mn shares), Citadel Advisors LLC (1.9Mn shares), Geode Capital Management, LLC (1.27Mn shares), Acadian Asset Management LLC (1.06Mn shares) and Clearstead Advisors, LLC (892.79K shares).