Madrigal Pharmaceuticals, Inc. (MDGL) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

0Shares Outstanding

2,581,631Shares held by institutions

$1,306,034,215Value of institutional holdings

105.15%Institutional ownership %

0.38%Shares Changed QoQ

305No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Madrigal Pharmaceuticals, Inc. (NASDAQ:MDGL) is held by 380 institutional investors per 13F filings through December 2025.

Their combined ownership stood at 103.1% of outstanding shares in December 2025, down from 105.5% in September 2025.
Their total shares held in MDGL increased 1.23% quarter over quarter, and separately, investors owning Madrigal Pharmaceuticals increased 35.71% from a year ago.
Among the 380 funds, 216 bought more Madrigal Pharmaceuticals shares, 113 sold down, and 51 held their ground.
In total, institutional investors held 23.18Mn shares in Madrigal Pharmaceuticals as of December 2025, up by 282.4K shares quarter on quarter, and down 346.02K shares year over year.
As of December 31, 2025, BAKER BROS. ADVISORS LP held the largest stake in Madrigal Pharmaceuticals with 2.14Mn shares, accounting for 9.53% of total shares outstanding.
Leading buyers of Madrigal Pharmaceuticals shares for the quarter ending December 2025 were NORGES BANK (196.39K), DEUTSCHE BANK AG\ (154.77K), ARMISTICE CAPITAL, LLC (145.72K), LORD, ABBETT & CO. LLC (142.65K), ALKEON CAPITAL MANAGEMENT LLC (120.0K).
The largest sellers of Madrigal Pharmaceuticals for the quarter ending December 2025 were Janus Henderson Group Plc (257.85K), PAULSON & CO. INC. (200.0K), UBS Group AG (114.7K), Morgan Stanley (99.18K), Affinity Asset Advisors, LLC (83.87K).
Per Business Quant, the top 10 investors in MDGL for the quarter ending December 2025 include BAKER BROS. ADVISORS LP (2.14Mn), RTW INVESTMENTS, LP (1.99Mn), VANGUARD GROUP INC (1.81Mn), Avoro Capital Advisors LLC (1.81Mn), PAULSON & CO. INC. (1.71Mn), BlackRock, Inc. (1.64Mn), Janus Henderson Group Plc (1.58Mn), State Street Corp (583.0K), WELLINGTON MANAGEMENT GROUP LLP (461.4K), GEODE CAPITAL MANAGEMENT, LLC (451.74K).

380 Institutional Holders

2,581,631 Total Shares Held

Rows:

Download Data

Owner Name	Date	Change (QoQ)	Change (%)	Value (USD)
BlackRock, Inc.	31 Dec, 2025	85,038	5.45%	$0.00
BAKER BROS. ADVISORS LP	31 Dec, 2025	0	0.00%	$0.00
Avoro Capital Advisors LLC	31 Dec, 2025	1,782,000	97.22%	$0.00
RTW INVESTMENTS, LP	31 Dec, 2025	0	0.00%	$0.00
WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC	31 Dec, 2025	-57,582	-13.98%	$0.00
Rockefeller Capital Management L.P.	31 Dec, 2025	20,871	113.12%	$0.00
VANGUARD GROUP INC	31 Dec, 2025	-3,160	-0.17%	$0.00
Polar Capital Holdings Plc	31 Dec, 2025	4,997	1.88%	$0.00
Barclays Plc	31 Dec, 2025	-51,471	-57.07%	$0.00
PAULSON & CO. INC.	31 Dec, 2025	-200,001	-10.48%	$0.00
Pictet Asset Management Holding SA	31 Dec, 2025	-9,847	-5.13%	$0.00
HSBC HOLDINGS PLC	31 Dec, 2025	2,200	0.00%	$0.00
Janus Henderson Group Plc	31 Dec, 2025	-257,847	-13.99%	$0.00
Erste Asset Management GmbH	31 Dec, 2025	-60,000	-29.84%	$0.00
PEAK6 LLC	31 Dec, 2025	154	0.00%	$0.00
State Street Corp	31 Dec, 2025	-75,094	-11.41%	$0.00
Point72 Asset Management, L.P.	31 Dec, 2025	85,202	206.64%	$0.00
WELLINGTON MANAGEMENT GROUP LLP	31 Dec, 2025	56,947	14.08%	$0.00
Woodline Partners LP	31 Dec, 2025	21,812	21.00%	$0.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	5,510	1.23%	$0.00

1 - 20 of 380

Research Tools