Madrigal Pharmaceuticals, Inc. (MDGL) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

22,482,502Shares Outstanding

25,312,031Shares held by institutions

$13,226,801,799Value of institutional holdings

112.59%Institutional ownership %

10.13%Shares Changed QoQ

380No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Madrigal Pharmaceuticals, Inc. (NASDAQ:MDGL) appears in 380 institutional 13F filings for the quarter ending December 2025.

They owned 103.1% of outstanding stock in December 2025, down from 105.5% the prior quarter.
They increased total shares held in Madrigal Pharmaceuticals by 1.23% from the prior quarter, while the number of investors in MDGL increased 35.71% year over year.
During the quarter, 216 of these 380 funds increased positions in MDGL, 113 reduced exposure, and 51 held steady.
Altogether, these fund groups held 23.18Mn shares in MDGL by December 2025, up by 282.4K shares quarter on quarter, and down 346.02K shares year over year.
Avoro Capital Advisors LLC is the top holder of Madrigal Pharmaceuticals as of December 31, 2025, with 3.62Mn shares representing 16.08% of outstanding stock.
The largest buyers of Madrigal Pharmaceuticals for the quarter ending December 2025 were Avoro Capital Advisors LLC (1.78Mn), Goldman Sachs Group Inc (225.58K), NORGES BANK (196.39K), DEUTSCHE BANK AG\ (154.77K), ARMISTICE CAPITAL, LLC (145.72K).
The largest sellers of Madrigal Pharmaceuticals for the quarter ending December 2025 were Janus Henderson Group Plc (257.85K), PAULSON & CO. INC. (200.0K), UBS Group AG (114.7K), Barclays Plc (101.38K), Morgan Stanley (99.18K).
Per Business Quant, the top 10 investors in MDGL for the quarter ending December 2025 include Avoro Capital Advisors LLC (3.62Mn), BAKER BROS. ADVISORS LP (2.14Mn), RTW INVESTMENTS, LP (1.99Mn), VANGUARD GROUP INC (1.81Mn), PAULSON & CO. INC. (1.71Mn), BlackRock, Inc. (1.64Mn), Janus Henderson Group Plc (1.58Mn), Goldman Sachs Group Inc (611.68K), State Street Corp (583.0K), WELLINGTON MANAGEMENT GROUP LLP (461.4K).

380 Institutional Holders

25,312,031 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
Avoro Capital Advisors LLC	31 Dec, 2025	3,615,000	1,782,000	97.22%	$2,105,159,100.00
BAKER BROS. ADVISORS LP	31 Dec, 2025	2,141,701	0	0.00%	$1,247,198,160.00
RTW INVESTMENTS, LP	31 Dec, 2025	1,993,687	0	0.00%	$1,161,003,688.00
VANGUARD GROUP INC	31 Dec, 2025	1,808,894	-3,160	-0.17%	$1,053,391,331.00
PAULSON & CO. INC.	31 Dec, 2025	1,707,522	-200,001	-10.48%	$994,358,361.00
BlackRock, Inc.	31 Dec, 2025	1,644,750	85,038	5.45%	$957,803,431.00
Janus Henderson Group Plc	31 Dec, 2025	1,584,843	-257,847	-13.99%	$918,203,904.00
Goldman Sachs Group Inc	31 Dec, 2025	611,678	225,578	58.42%	$356,204,568.00
State Street Corp	31 Dec, 2025	583,003	-75,094	-11.41%	$339,505,967.00
WELLINGTON MANAGEMENT GROUP LLP	31 Dec, 2025	461,402	56,947	14.08%	$268,692,841.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	451,743	5,510	1.23%	$263,113,834.00
FMR LLC	31 Dec, 2025	439,398	38,262	9.54%	$255,879,233.00
Bank Of America Corp /De/	31 Dec, 2025	416,025	-72,559	-14.85%	$242,267,998.00
Invesco Ltd.	31 Dec, 2025	365,314	65,749	21.95%	$212,736,955.00
WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC	31 Dec, 2025	354,220	-57,582	-13.98%	$206,276,475.00
Polar Capital Holdings Plc	31 Dec, 2025	270,151	4,997	1.88%	$157,319,733.00
ARMISTICE CAPITAL, LLC	31 Dec, 2025	265,705	145,723	121.45%	$154,730,650.00
Hood River Capital Management LLC	31 Dec, 2025	247,560	4,752	1.96%	$144,164,090.00
LORD, ABBETT & CO. LLC	31 Dec, 2025	244,796	142,653	139.66%	$142,555.00
ALKEON CAPITAL MANAGEMENT LLC	31 Dec, 2025	240,000	120,000	100.00%	$139,761,600.00

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