Madrigal Pharmaceuticals, Inc. (MDGL) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

22,289,014Shares Outstanding

2,520,318Shares held by institutions

$1,440,210,518Value of institutional holdings

106.61%Institutional ownership %

-0.15%Shares Changed QoQ

347No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

A total of 347 institutions have reported a stake in Madrigal Pharmaceuticals, Inc. (NASDAQ:MDGL) as of September 2025, according to recent 13F filings with the SEC.

These investors collectively held 106.6% of the company's total shares outstanding in September 2025, down from 107.6% in June 2025.
The company experienced a -0.15% quarterly change in institutional shares held, alongside an increase of 33.98% in total owners annually.
Of these 347 institutional investors, 165 increased their holdings in Madrigal Pharmaceuticals, while 132 of them reduced positions, and 50 investors maintained their exposure.
This class of investors decreased its holdings in Madrigal Pharmaceuticals to 23.76Mn shares for the 13F-cycle ending September 2025, down by 35.42K shares quarter on quarter, and up 541.00K shares year over year.
BAKER BROS. ADVISORS LP's holding of 2.14Mn shares as of September 30, 2025 makes it the primary institutional investor in Madrigal Pharmaceuticals, owning 9.61% of the stock.
Among the most significant buyers of Madrigal Pharmaceuticals during September 2025 were WELLINGTON MANAGEMENT GROUP LLP (397.08K), GOLDMAN SACHS GROUP INC (196.26K), BAKER BROS. ADVISORS LP (165.68K), BlackRock, Inc. (120.99K), ALKEON CAPITAL MANAGEMENT LLC (120.00K).
Leading sellers of Madrigal Pharmaceuticals stock in September 2025 included JANUS HENDERSON GROUP PLC (349.06K), UBS Group AG (288.37K), ADAGE CAPITAL PARTNERS GP, L.L.C. (287.66K), PAULSON & CO. INC. (182.00K), PRICE T ROWE ASSOCIATES INC /MD/ (155.94K).
The top 10 institutional holders of Madrigal Pharmaceuticals for the quarter ending September 2025 included BAKER BROS. ADVISORS LP (2.14Mn), RTW INVESTMENTS, LP (1.99Mn), PAULSON & CO. INC. (1.91Mn), JANUS HENDERSON GROUP PLC (1.84Mn), Avoro Capital Advisors LLC (1.83Mn), VANGUARD GROUP INC (1.81Mn), BlackRock, Inc. (1.56Mn), STATE STREET CORP (658.10K), GEODE CAPITAL MANAGEMENT, LLC (446.23K), WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC (411.80K).

347 Institutional Holders

2,520,318 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
BAKER BROS. ADVISORS LP	30 Sep, 2025	2,141,701	165,683	8.38%	$982,312,581.00
RTW INVESTMENTS, LP	30 Sep, 2025	1,993,687	0	0.00%	$914,424,479.00
PAULSON & CO. INC.	30 Sep, 2025	1,907,523	-182,000	-8.71%	$874,904,499.00
JANUS HENDERSON GROUP PLC	30 Sep, 2025	1,842,690	-349,063	-15.93%	$845,277,273.00
Avoro Capital Advisors LLC	30 Sep, 2025	1,833,000	-42,000	-2.24%	$840,723,780.00
VANGUARD GROUP INC	30 Sep, 2025	1,812,054	-65,227	-3.47%	$831,116,688.00
BlackRock, Inc.	30 Sep, 2025	1,559,712	120,988	8.41%	$715,377,705.00
STATE STREET CORP	30 Sep, 2025	658,097	-32,618	-4.72%	$301,842,770.00
GEODE CAPITAL MANAGEMENT, LLC	30 Sep, 2025	446,233	31,841	7.68%	$204,700,716.00
WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC	30 Sep, 2025	411,802	61,513	17.56%	$188,877,105.00
WELLINGTON MANAGEMENT GROUP LLP	30 Sep, 2025	404,455	397,076	5,381.16%	$185,507,331.00
FMR LLC	30 Sep, 2025	401,136	-44,203	-9.93%	$183,985,076.00
GOLDMAN SACHS GROUP INC	30 Sep, 2025	386,100	196,260	103.38%	$177,088,626.00
PRICE T ROWE ASSOCIATES INC /MD/	30 Sep, 2025	352,520	-155,944	-30.67%	$161,688.00
Invesco Ltd.	30 Sep, 2025	299,565	99,209	49.52%	$137,398,483.00
JANE STREET GROUP, LLC	30 Sep, 2025	296,434	-63,166	-17.57%	$135,962,419.00
Polar Capital Holdings Plc	30 Sep, 2025	265,154	39,744	17.63%	$121,615,534.00
MORGAN STANLEY	30 Sep, 2025	249,647	1,685	0.68%	$114,503,407.00
BANK OF AMERICA CORP /DE/	30 Sep, 2025	244,292	-32,929	-11.88%	$112,046,969.00
Hood River Capital Management LLC	30 Sep, 2025	242,808	-1,930	-0.79%	$111,366,317.00

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Madrigal Pharmaceuticals, Inc. (MDGL) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

347 Institutional Holders

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