Madrigal Pharmaceuticals, Inc. (NASDAQ:MDGL) showed up in the 13F filings of 380 institutional investors as of December 2025.
| Owner Name | Date | Shares Held | Change (QoQ) | Change (%) | Value (USD) |
|---|---|---|---|---|---|
| Janus Henderson Group Plc | 31 Mar, 2026 | 4,037,294 | 2,452,451 | 154.74% | $2,103,454,952.00 |
| Avoro Capital Advisors LLC | 31 Mar, 2026 | 3,615,000 | 1,782,000 | 97.22% | $2,105,159,100.00 |
| BAKER BROS. ADVISORS LP | 31 Mar, 2026 | 2,141,701 | 0 | 0.00% | $1,247,198,160.00 |
| BAKER BROS. ADVISORS LP | 31 Mar, 2026 | 2,141,701 | 0 | 0.00% | $1,121,116,222.00 |
| RTW INVESTMENTS, LP | 31 Mar, 2026 | 1,993,687 | 0 | 0.00% | $1,161,003,688.00 |
| RTW INVESTMENTS, LP | 31 Mar, 2026 | 1,993,687 | 0 | 0.00% | $1,043,635,334.00 |
| Avoro Capital Advisors LLC | 31 Mar, 2026 | 1,818,181 | -1,796,819 | -49.70% | $951,763,208.00 |
| VANGUARD GROUP INC | 31 Mar, 2026 | 1,808,894 | -3,160 | -0.17% | $1,053,391,331.00 |
| PAULSON & CO. INC. | 31 Mar, 2026 | 1,707,522 | -200,001 | -10.48% | $994,358,361.00 |
| BlackRock, Inc. | 31 Mar, 2026 | 1,644,750 | 85,038 | 5.45% | $957,803,431.00 |
| Janus Henderson Group Plc | 31 Mar, 2026 | 1,584,843 | -257,847 | -13.99% | $918,203,904.00 |
| BlackRock, Inc. | 31 Mar, 2026 | 1,559,965 | -84,785 | -5.15% | $816,594,622.00 |
| PAULSON & CO. INC. | 31 Mar, 2026 | 1,392,188 | -315,334 | -18.47% | $728,768,652.00 |
| VANGUARD PORTFOLIO MANAGEMENT LLC | 31 Mar, 2026 | 841,145 | 841,145 | 0.00% | $440,314,173.00 |
| VANGUARD CAPITAL MANAGEMENT LLC | 31 Mar, 2026 | 827,144 | 827,144 | 0.00% | $432,985,070.00 |
| WELLINGTON MANAGEMENT GROUP LLP | 31 Mar, 2026 | 694,958 | 233,556 | 50.62% | $363,789,664.00 |
| Goldman Sachs Group Inc | 31 Mar, 2026 | 611,678 | 225,578 | 58.42% | $356,204,568.00 |
| State Street Corp | 31 Mar, 2026 | 609,525 | 26,522 | 4.55% | $319,068,052.00 |
| State Street Corp | 31 Mar, 2026 | 583,003 | -75,094 | -11.41% | $339,505,967.00 |
| FMR LLC | 31 Mar, 2026 | 511,728 | 72,330 | 16.46% | $267,873,994.00 |