INSMED Inc (INSM) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

211,440,571Shares Outstanding

1,014,921Shares held by institutions

$152,765,909Value of institutional holdings

97.86%Institutional ownership %

5.08%Shares Changed QoQ

639No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Recent 13F filings as of December 2025 show that 639 institutional investors hold a position in INSMED Inc (NASDAQ:INSM).

Institutional ownership in Insmed edged down to 97.9% in December 2025, compared to 101.6% in September 2025.
The company experienced a 5.08% quarterly change in institutional shares held, alongside an increase of 46.90% in total owners annually.
The latest 13F cycle for Insmed reveals that of 639 total investors, 413 funds grew their exposure, whereas 173 reduced theirs and 53 made no changes.
The aggregate institutional position in Insmed now stands at 206.92Mn shares as of December 2025, after investors increased their holdings (up by 10.00Mn shares quarter on quarter which is up 12.20Mn shares year over year).
As of December 31, 2025, JPMORGAN CHASE & CO held Insmed's largest shareholding position with over 23.20Mn shares, representing 10.97% of total outstanding shares.
Among the most significant buyers of Insmed during December 2025 were NORGES BANK (2.91Mn), BlackRock, Inc. (2.70Mn), RTW INVESTMENTS, LP (1.76Mn), STATE STREET CORP (1.22Mn), NOMURA ASSET MANAGEMENT INTERNATIONAL INC. (1.18Mn).
Leading sellers of Insmed stock in December 2025 included Capital International Investors (2.40Mn), D. E. Shaw & Co., Inc. (1.31Mn), Artia Global Partners LP (1.16Mn), MILLENNIUM MANAGEMENT LLC (1.02Mn), ADAGE CAPITAL PARTNERS GP, L.L.C. (952.50K).
The top 10 institutional holders of Insmed for the quarter ending December 2025 included JPMORGAN CHASE & CO (23.20Mn), VANGUARD GROUP INC (21.08Mn), Darwin Global Management, Ltd. (20.93Mn), BlackRock, Inc. (15.07Mn), FMR LLC (9.93Mn), BAKER BROS. ADVISORS LP (6.59Mn), STATE STREET CORP (5.20Mn), Capital International Investors (5.15Mn), Artisan Partners Limited Partnership (4.84Mn), RTW INVESTMENTS, LP (4.84Mn).

639 Institutional Holders

1,014,921 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
JPMORGAN CHASE & CO	31 Dec, 2025	23,199,512	151,836	0.66%	$4,037,643,311.00
VANGUARD GROUP INC	31 Dec, 2025	21,076,344	1,140,524	5.72%	$3,668,126,910.00
Darwin Global Management, Ltd.	31 Dec, 2025	20,933,277	475,832	2.33%	$3,644,274,193.00
BlackRock, Inc.	31 Dec, 2025	15,065,052	2,700,148	21.84%	$2,621,921,693.00
FMR LLC	31 Dec, 2025	9,927,936	746,973	8.14%	$1,727,857,942.00
BAKER BROS. ADVISORS LP	31 Dec, 2025	6,592,746	-110,738	-1.65%	$1,147,401,514.00
STATE STREET CORP	31 Dec, 2025	5,201,744	1,217,390	30.55%	$905,311,526.00
Capital International Investors	31 Dec, 2025	5,151,671	-2,402,182	-31.80%	$896,597,082.00
Artisan Partners Limited Partnership	31 Dec, 2025	4,843,749	-93,934	-1.90%	$843,006,016.00
RTW INVESTMENTS, LP	31 Dec, 2025	4,842,879	1,758,321	57.00%	$842,854,661.00
D. E. Shaw & Co., Inc.	31 Dec, 2025	4,350,995	-1,306,469	-23.09%	$757,247,170.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	4,299,052	539,625	14.35%	$751,935,864.00
Orbis Allan Gray Ltd	31 Dec, 2025	4,179,957	929,089	28.58%	$727,479,716.00
NORGES BANK	31 Dec, 2025	2,910,971	2,910,971	0.00%	$506,625,393.00
FRANKLIN RESOURCES INC	31 Dec, 2025	2,755,536	615,811	28.78%	$479,573,482.00
AMERIPRISE FINANCIAL INC	31 Dec, 2025	1,968,857	-753,022	-27.67%	$342,660,797.00
UBS Group AG	31 Dec, 2025	1,950,835	304,596	18.50%	$339,523,322.00
BANK OF AMERICA CORP /DE/	31 Dec, 2025	1,725,681	123,875	7.73%	$300,337,528.00
MORGAN STANLEY	31 Dec, 2025	1,631,906	668,275	69.35%	$284,017,467.00
Duquesne Family Office LLC	31 Dec, 2025	1,481,752	-941,683	-38.86%	$257,884.00

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