As of September 29, 2026, Insmed's top three insider holders are Steinar J Engelsen (Director, 320.80K shares), William Lewis (Chair And Ceo, 259.06K shares), Melvin Md Sharoky (Director, 246.08K shares).
| # | Insider | Position | Direct | Indirect | Total | Share of Insiders | Last Filed |
|---|---|---|---|---|---|---|---|
| 1 | Steinar J Engelsen | Director | 320,802 | 0 | 320,802 | 17.4% | 03 Nov, 2021 |
| 2 | William Lewis | Chair And Ceo | 259,058 | 0 | 259,058 | 14.1% | 24 Jul, 2026 |
| 3 | Melvin Md Sharoky | Director | 246,081 | 0 | 246,081 | 13.4% | 15 May, 2026 |
| 4 | John Drayton Wise | Chief Commercial Officer | 236,999 | 0 | 236,999 | 12.9% | 07 Feb, 2025 |
| 5 | Roger Adsett | Chief Operating Officer | 98,744 | 0 | 98,744 | 5.4% | 12 Aug, 2026 |
| 6 | David W J Mcgirr | Director | 44,323 | 53,400 | 97,723 | 5.3% | 11 Feb, 2026 |
| 7 | Clarissa Desjardins | Director | 70,312 | 0 | 70,312 | 3.8% | 15 May, 2026 |
| 8 | Alfred Altomari | Director | 69,495 | 0 | 69,495 | 3.8% | 15 May, 2024 |
| 9 | Sara Bonstein | Chief Financial Officer | 69,082 | 0 | 69,082 | 3.8% | 05 Jun, 2026 |
| 10 | Carol Schafer | Director | 66,622 | 0 | 66,622 | 3.6% | 15 May, 2026 |
| 11 | Elizabeth M Anderson | Director | 62,034 | 0 | 62,034 | 3.4% | 15 May, 2026 |
| 12 | Martina M.D. Flammer | Chief Medical Officer | 60,486 | 0 | 60,486 | 3.3% | 07 Aug, 2026 |
| 13 | Leo Lee | Director | 57,971 | 0 | 57,971 | 3.1% | 15 May, 2026 |
| 14 | Orlov S Nicole Schaeffer | Chief People Strategy Officer | 41,754 | 0 | 41,754 | 2.3% | 06 Jan, 2026 |
| 15 | David R Brennan | Director | 39,238 | 0 | 39,238 | 2.1% | 11 Sep, 2026 |
| 16 | Michael Alexander Smith | Chief Legal Officer | 37,648 | 0 | 37,648 | 2.0% | 24 Jun, 2026 |
| 17 | Samuele Butera | Svp, Gm, Global Respiratory | 7,342 | 0 | 7,342 | 0.4% | 24 Jun, 2026 |
Each row is that insider’s most recently reported position, from Form 4 filings over the last 60 months — which is why this total does not tie to the quarterly series above, where a quarter counts only the insiders who filed in it. Shares held through a fund or institutional portfolio are counted on the institutional ownership page instead.
| Date | Insider | Position | Transaction | Shares | Price | Value | Shares Held After | Ownership |
|---|---|---|---|---|---|---|---|---|
| 09 Sep, 2026 | David R Brennan | Director | Disposed S | 25,000 | $124.00 | $3.10Mn | 39,238 | Direct |
| 17 Aug, 2026 | Melvin Md Sharoky | Director | Disposed S | 5,000 | $127.53 | $637.65K | 0 | Indirect |
| 10 Aug, 2026 | Roger Adsett | Chief Operating Officer | Acquired M | 82,280 | $13.67 | $1.12Mn | 181,024 | Direct |
| 10 Aug, 2026 | Roger Adsett | Chief Operating Officer | Acquired M | 76,600 | $17.16 | $1.31Mn | 257,624 | Direct |
| 10 Aug, 2026 | Roger Adsett | Chief Operating Officer | Acquired M | 80,970 | $30.46 | $2.47Mn | 338,594 | Direct |
| 10 Aug, 2026 | Roger Adsett | Chief Operating Officer | Disposed S | 239,850 | $133.27 | $31.96Mn | 98,744 | Direct |
| 10 Aug, 2026 | Roger Adsett | Chief Operating Officer | Disposed M | 82,280 | $0.00 | $0 | 0 | Direct |
| 10 Aug, 2026 | Roger Adsett | Chief Operating Officer | Disposed M | 76,600 | $0.00 | $0 | 0 | Direct |
| 10 Aug, 2026 | Roger Adsett | Chief Operating Officer | Disposed M | 80,970 | $0.00 | $0 | 0 | Direct |
| 06 Aug, 2026 | Martina M.D. Flammer | Chief Medical Officer | Acquired M | 18,278 | $18.95 | $346.37K | 78,764 | Direct |
| 06 Aug, 2026 | Martina M.D. Flammer | Chief Medical Officer | Acquired M | 8,895 | $25.83 | $229.76K | 87,659 | Direct |
| 06 Aug, 2026 | Martina M.D. Flammer | Chief Medical Officer | Disposed S | 8,895 | $127.00 | $1.13Mn | 78,764 | Direct |
| 06 Aug, 2026 | Martina M.D. Flammer | Chief Medical Officer | Disposed S | 18,278 | $129.40 | $2.37Mn | 60,486 | Direct |
| 06 Aug, 2026 | Martina M.D. Flammer | Chief Medical Officer | Disposed M | 18,278 | $0.00 | $0 | 36,555 | Direct |
| 06 Aug, 2026 | Martina M.D. Flammer | Chief Medical Officer | Disposed M | 8,895 | $0.00 | $0 | 35,580 | Direct |
| 23 Jul, 2026 | William Lewis | Chair And Ceo | Acquired M | 6,260 | $30.46 | $190.68K | 265,318 | Direct |
| 23 Jul, 2026 | William Lewis | Chair And Ceo | Acquired M | 4,440 | $17.16 | $76.19K | 269,758 | Direct |
| 23 Jul, 2026 | William Lewis | Chair And Ceo | Disposed S | 4,828 | $105.62 | $509.93K | 264,930 | Direct |
| 23 Jul, 2026 | William Lewis | Chair And Ceo | Disposed S | 5,872 | $106.43 | $624.96K | 259,058 | Direct |
| 23 Jul, 2026 | William Lewis | Chair And Ceo | Disposed M | 6,260 | $0.00 | $0 | 0 | Direct |