Based on data from the past 90 days ending December 12, 2025, INSMED's three largest insider shareholders are Chair And CEO William Lewis (537.84K shares), Director Melvin Md Sharoky (244.69K shares), Director David R Brennan (126.93K shares).
| Holder | Position | Shares | Report Date |
|---|---|---|---|
| William Lewis | Chair And CEO | 537,835 | 05 Dec, 2025 |
| Steinar J Engelsen | 320,802 | 03 Nov, 2021 | |
| Melvin Md Sharoky | 244,689 | 09 Dec, 2025 | |
| Christine A Pellizzari | Chief Legal Officer | 149,985 | 18 May, 2021 |
| John Drayton Wise | Chief Commercial Officer | 133,015 | 07 Feb, 2025 |
| David R Brennan | 126,933 | 10 Nov, 2025 | |
| Roger Adsett | Chief Operating Officer | 105,637 | 21 Aug, 2025 |
| David W J Mcgirr | 97,723 | 04 Jun, 2025 | |
| Martina M.D. Flammer | Chief Medical Officer | 83,111 | 03 Dec, 2025 |
| Sara Bonstein | Chief Financial Officer | 73,505 | 23 Jul, 2025 |
| Clarissa Desjardins | 70,032 | 19 May, 2025 | |
| Alfred Altomari | 69,495 | 15 May, 2024 | |
| Carol Schafer | 63,317 | 19 May, 2025 | |
| Elizabeth M Anderson | 58,729 | 26 Nov, 2025 | |
| Michael Alexander Smith | Chief Legal Officer | 54,902 | 05 Nov, 2025 |
| Leo Lee | 54,677 | 18 Nov, 2025 | |
| Orlov S Nicole Schaeffer | Chief People Strategy Officer | 36,461 | 14 Nov, 2025 |
| John Soriano | Chief Compliance Officer | 35,204 | 09 Sep, 2021 |
* Please note that the shares above only reflect shares from the fund portfolio and the institutional portfolio. Shares from the personal portfolio are excluded from this Institutional Ownership Page. See these insiders' latest transactions here on Insider Page.
| Transaction Date | Insider Name | Security Class | Transaction Type | Shares Traded | Price | Shares Remaining | Ownership | Code |
|---|---|---|---|---|---|---|---|---|
| 05 Dec, 2025 | Melvin Md Sharoky | Common Stock | D | 20,000 | $205.01 | 243,948 | D | S |
| 04 Dec, 2025 | William Lewis | Common Stock | A | 6,259 | $30.46 | 310,170 | D | M |
| 04 Dec, 2025 | William Lewis | Common Stock | A | 4,440 | $17.16 | 314,610 | D | M |
| 04 Dec, 2025 | William Lewis | Common Stock | D | 4,516 | $204.62 | 310,094 | D | S |
| 04 Dec, 2025 | William Lewis | Common Stock | D | 2,222 | $205.66 | 307,872 | D | S |
| 04 Dec, 2025 | William Lewis | Common Stock | D | 2,921 | $206.49 | 304,951 | D | S |
| 04 Dec, 2025 | William Lewis | Common Stock | D | 1,040 | $207.42 | 303,911 | D | S |
| 01 Dec, 2025 | Martina M.D. Flammer | Common Stock | A | 8,895 | $25.83 | 92,006 | D | M |
| 01 Dec, 2025 | Martina M.D. Flammer | Common Stock | D | 1,450 | $205.98 | 90,556 | D | S |
| 01 Dec, 2025 | Martina M.D. Flammer | Common Stock | D | 5,886 | $207.03 | 84,670 | D | S |
| 01 Dec, 2025 | Martina M.D. Flammer | Common Stock | D | 1,559 | $207.73 | 83,111 | D | S |
| 24 Nov, 2025 | Elizabeth M Anderson | Common Stock | D | 5,000 | $204.58 | 58,729 | D | S |
| 17 Nov, 2025 | Leo Lee | Common Stock | D | 3,212 | $193.51 | 126,465 | D | S |
| 17 Nov, 2025 | Leo Lee | Common Stock | D | 17,594 | $194.49 | 108,871 | D | S |
| 17 Nov, 2025 | Leo Lee | Common Stock | D | 14,944 | $195.39 | 93,927 | D | S |
| 17 Nov, 2025 | Leo Lee | Common Stock | D | 24,076 | $196.61 | 69,851 | D | S |
| 17 Nov, 2025 | Leo Lee | Common Stock | D | 15,174 | $197.40 | 54,677 | D | S |
| 14 Nov, 2025 | Elizabeth M Anderson | Common Stock | D | 10,000 | $195.87 | 63,729 | D | S |
| 12 Nov, 2025 | Orlov S Nicole Schaeffer | Common Stock | A | 30,000 | $26.46 | 66,461 | D | M |
| 12 Nov, 2025 | Orlov S Nicole Schaeffer | Common Stock | D | 4,078 | $192.45 | 62,383 | D | S |