Zymeworks (ZYME) Return on Sales (2021 - 2026)
Zymeworks recorded quarterly Return on Sales of 0.18% in Q1 2026, down 11.93% quarter-over-quarter from 0.16% in Q4 2025, and down 11.0% year-over-year from 0.21% in Q1 2025.
Zymeworks' Return on Sales history runs 6 years deep, the most recent figure standing at 0.18% for Q1 2026.
- In Q1 2026, Return on Sales fell 11.0% year-over-year to 0.18%; the TTM figure through Mar 2026 stood at 0.01% (up 1.0% YoY), while the FY2025 annual figure was 0.01%, up 1.0% from the prior year.
- Return on Sales came in at 0.18% for Q1 2026 at Zymeworks, down from 0.16% in the prior quarter.
- In the past five years, Return on Sales ranged from a high of 0.01% in Q4 2022 to a low of 0.38% in Q1 2022.
- A 5-year average of 0.08% and a median of 0.03% in 2024 frame the typical range for Return on Sales.
- Across the five-year window, Return on Sales jumped 37 bps in 2023 and retreated 16 bps in 2025, its largest moves.
- Zymeworks' Return on Sales stood at 0.01% in 2022, then slumped by 190 bps to 0.01% in 2023, then advanced by 11 bps to 0.01% in 2024, then sank by 2063 bps to 0.16% in 2025, then fell by 12 bps to 0.18% in 2026.
- According to Business Quant data, Return on Sales over the past three periods registered 0.18%, 0.16%, and 0.01% for Q1 2026, Q4 2025, and Q3 2025 respectively.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROS (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 961,148.99 Bn | 961,148.98 Bn | - | - |
| 2 | Alterity Therapeutics | 744,933.29 Bn | 744,933.26 Bn | - | - |
| 3 | Legend Biotech | 2,540.00 Bn | 2,539.71 Bn | 242.10 Mn | 0.00% |
| 4 | Nanobiotix | 2,199.85 Bn | 2,199.78 Bn | - | - |
| 5 | Akari Therapeutics | 1,635.88 Bn | 1,635.88 Bn | - | - |
| 6 | Vertex Pharmaceuticals | 111.32 Bn | 104.07 Bn | 2.59 Bn | 0.00% |
| 7 | Evaxion A | 62.56 Bn | 62.54 Bn | - | 0.00% |
| 8 | Regeneron Pharmaceuticals | 62.55 Bn | 53.79 Bn | 3.31 Bn | 0.00% |
| 9 | Alnylam Pharmaceuticals | 39.57 Bn | 36.56 Bn | 959.66 Mn | 0.00% |
| 10 | Zymeworks | 1.84 Bn | 1.47 Bn | - | -0.18% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -0.18% |
| Dec 31, 2025 | -0.16% |
| Sep 30, 2025 | -0.01% |
| Jun 30, 2025 | 0.00% |
| Mar 31, 2025 | -0.07% |
| Dec 31, 2024 | -0.01% |
| Sep 30, 2024 | -0.02% |
| Jun 30, 2024 | -0.05% |
| Mar 31, 2024 | -0.03% |
| Dec 31, 2023 | -0.01% |
| Sep 30, 2023 | -0.02% |
| Jun 30, 2023 | -0.07% |
| Mar 31, 2023 | -0.01% |
| Dec 31, 2022 | 0.01% |
| Sep 30, 2022 | -0.18% |
| Jun 30, 2022 | -0.12% |
| Mar 31, 2022 | -0.38% |
| Dec 31, 2021 | -0.05% |
| Sep 30, 2021 | -0.14% |