Growth Metrics

Zymeworks (ZYME) Return on Sales (2021 - 2026)

Zymeworks recorded quarterly Return on Sales of 0.18% in Q1 2026, down 11.93% quarter-over-quarter from 0.16% in Q4 2025, and down 11.0% year-over-year from 0.21% in Q1 2025.

Zymeworks' Return on Sales history runs 6 years deep, the most recent figure standing at 0.18% for Q1 2026.

  • In Q1 2026, Return on Sales fell 11.0% year-over-year to 0.18%; the TTM figure through Mar 2026 stood at 0.01% (up 1.0% YoY), while the FY2025 annual figure was 0.01%, up 1.0% from the prior year.
  • Return on Sales came in at 0.18% for Q1 2026 at Zymeworks, down from 0.16% in the prior quarter.
  • In the past five years, Return on Sales ranged from a high of 0.01% in Q4 2022 to a low of 0.38% in Q1 2022.
  • A 5-year average of 0.08% and a median of 0.03% in 2024 frame the typical range for Return on Sales.
  • Across the five-year window, Return on Sales jumped 37 bps in 2023 and retreated 16 bps in 2025, its largest moves.
  • Zymeworks' Return on Sales stood at 0.01% in 2022, then slumped by 190 bps to 0.01% in 2023, then advanced by 11 bps to 0.01% in 2024, then sank by 2063 bps to 0.16% in 2025, then fell by 12 bps to 0.18% in 2026.
  • According to Business Quant data, Return on Sales over the past three periods registered 0.18%, 0.16%, and 0.01% for Q1 2026, Q4 2025, and Q3 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROS (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn 0.00%
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 0.00%
7 Evaxion A 62.56 Bn 62.54 Bn - 0.00%
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 0.00%
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 0.00%
10 Zymeworks 1.84 Bn 1.47 Bn - -0.18%

Historic Data

Download Data 🔒
DateValue
Mar 31, 2026 -0.18%
Dec 31, 2025 -0.16%
Sep 30, 2025 -0.01%
Jun 30, 2025 0.00%
Mar 31, 2025 -0.07%
Dec 31, 2024 -0.01%
Sep 30, 2024 -0.02%
Jun 30, 2024 -0.05%
Mar 31, 2024 -0.03%
Dec 31, 2023 -0.01%
Sep 30, 2023 -0.02%
Jun 30, 2023 -0.07%
Mar 31, 2023 -0.01%
Dec 31, 2022 0.01%
Sep 30, 2022 -0.18%
Jun 30, 2022 -0.12%
Mar 31, 2022 -0.38%
Dec 31, 2021 -0.05%
Sep 30, 2021 -0.14%