Zymeworks (ZYME) Return on Sales (2021 - 2026)

Zymeworks (ZYME) reported Return on Sales of 0.18% for Q1 2026, down 18.0% on a YoY basis from 0.22% in Q1 2025, and down 11.93% sequentially from 0.16% in Q4 2025.

Zymeworks (ZYME) Return on Sales (2021 - 2026) Analysis & Trends

Zymeworks (ZYME) has 6 years of Return on Sales data on file, last reported at 0.18% in Q1 2026.

  • For the quarter ending Q1 2026, Return on Sales fell 18.0% year-over-year to 0.18%; the trailing twelve-month figure through Mar 2026 stood at 0.01% (changed 0.0% YoY), and the FY2025 full-year result was 0.01%, up 1.0% from the prior year.
  • Return on Sales slipped to 0.18% in Q1 2026, from 0.16% in the prior quarter.
  • In the past five years, Return on Sales ranged from a high of 0.01% in Q4 2022 to a low of 0.38% in Q1 2022.
  • A 5-year average of 0.07% and a median of 0.02% in 2024 frame the typical range for Return on Sales.
  • Across the five-year window, Return on Sales soared 37 bps in 2023 and dropped 18 bps in 2026, its largest moves.
  • Tracing ZYME's Return on Sales over 5 years: stood at 0.01% in 2022, then plunged by 190 bps to 0.01% in 2023, then rose by 11 bps to 0.01% in 2024, then tumbled by 2063 bps to 0.16% in 2025, then dropped by 12 bps to 0.18% in 2026.
  • Business Quant data shows ZYME's Return on Sales at 0.18% in Q1 2026, 0.16% in Q4 2025, and 0.01% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROS (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 0.00%
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 0.00%
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 0.00%
7 Belite Bio 61.40 Bn 61.40 Bn - -
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn 0.00%
9 Revolution Medicines 37.37 Bn 37.37 Bn - -
10 Zymeworks 1.70 Bn 1.34 Bn - -0.18%

Historic Data

Download Data
DateValue
Mar 31, 2026 -0.18%
Dec 31, 2025 -0.16%
Sep 30, 2025 -0.01%
Jun 30, 2025 0.00%
Mar 31, 2025 -0.01%
Dec 31, 2024 -0.01%
Sep 30, 2024 -0.02%
Jun 30, 2024 -0.02%
Mar 31, 2024 -0.03%
Dec 31, 2023 -0.01%
Sep 30, 2023 -0.02%
Jun 30, 2023 -0.07%
Mar 31, 2023 -0.01%
Dec 31, 2022 0.01%
Sep 30, 2022 -0.18%
Jun 30, 2022 -0.12%
Mar 31, 2022 -0.38%
Dec 31, 2021 -0.05%
Sep 30, 2021 -0.14%