Zymeworks (ZYME) Return on Sales (2021 - 2026)

Zymeworks (ZYME) posted Return on Sales of 0.18% for Q1 2026, down 11.93% sequentially from 0.16% in Q4 2025, and down 18.0% YoY from 0.22% in Q1 2025.

Zymeworks (ZYME) Return on Sales (2021 - 2026) Analysis & Trends

Zymeworks has reported Return on Sales for 6 years, with the latest figure at 0.18% in Q1 2026.

  • Quarterly Return on Sales fell 18.0% year-over-year to 0.18% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 0.01% (changed 0.0% YoY) and the FY2025 annual result came in at 0.01%, up 1.0% from the prior year.
  • Return on Sales slipped to 0.18% in Q1 2026 per ZYME's latest filing, from 0.16% in the prior quarter.
  • Over five years, Return on Sales peaked at 0.01% in Q4 2022 and troughed at 0.38% in Q1 2022.
  • A 5-year average of 0.07% and a median of 0.02% in 2024 frame the typical range for Return on Sales.
  • The sharpest annual moves came in 2023 and 2026: Return on Sales surged 37 bps in 2023, then fell 18 bps in 2026.
  • Over 5 years, Return on Sales stood at 0.01% in 2022, then tumbled by 190 bps to 0.01% in 2023, then climbed by 11 bps to 0.01% in 2024, then slumped by 2063 bps to 0.16% in 2025, then retreated by 12 bps to 0.18% in 2026.
  • According to Business Quant data, Return on Sales over the past three periods registered 0.18%, 0.16%, and 0.01% for Q1 2026, Q4 2025, and Q3 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROS (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 0.00%
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 0.00%
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 0.00%
4 Revolution Medicines 43.64 Bn 43.64 Bn - -
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 0.00%
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn 0.00%
7 Royalty Pharma 33.72 Bn 35.84 Bn - 0.00%
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 0.00%
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn 0.00%
10 Zymeworks 1.79 Bn 1.52 Bn - -0.10%

Historic Data

Download Data
DateValue
Jun 30, 2026 -0.10%
Mar 31, 2026 -0.18%
Dec 31, 2025 -0.16%
Sep 30, 2025 -0.01%
Jun 30, 2025 0.00%
Mar 31, 2025 -0.01%
Dec 31, 2024 -0.01%
Sep 30, 2024 -0.02%
Jun 30, 2024 -0.02%
Mar 31, 2024 -0.03%
Dec 31, 2023 -0.01%
Sep 30, 2023 -0.02%
Jun 30, 2023 -0.07%
Mar 31, 2023 -0.01%
Dec 31, 2022 0.01%
Sep 30, 2022 -0.18%
Jun 30, 2022 -0.12%
Mar 31, 2022 -0.38%
Dec 31, 2021 -0.05%
Sep 30, 2021 -0.14%