Zymeworks (ZYME) Return on Sales (2021 - 2026)
Zymeworks' (ZYME) quarterly Return on Sales came in at 0.18% in Q1 2026, down 11.0% year-on-year from 0.21% in Q1 2025, and down 11.93% quarter-over-quarter from 0.16% in Q4 2025.
Zymeworks (ZYME) Return on Sales (2021 - 2026) Analysis & Trends
Zymeworks has disclosed Return on Sales across 6 years of filings, most recently posting 0.18% for Q1 2026.
- Return on Sales for Q1 2026 came in at 0.18%, down 11.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 0.01% (up 1.0% YoY), and the FY2025 annual result was 0.01%, up 1.0% from the prior year.
- Return on Sales came in at 0.18% for Q1 2026 at Zymeworks, down from 0.16% in the prior quarter.
- In the past five years, Return on Sales ranged from a high of 0.01% in Q4 2022 to a low of 0.38% in Q1 2022.
- The 5-year median for Return on Sales is 0.03% (2024), against an average of 0.08%.
- Across the five-year window, Return on Sales soared 37 bps in 2023 and fell 16 bps in 2025, its largest moves.
- Zymeworks' Return on Sales stood at 0.01% in 2022, then tumbled by 190 bps to 0.01% in 2023, then gained by 11 bps to 0.01% in 2024, then slumped by 2063 bps to 0.16% in 2025, then declined by 12 bps to 0.18% in 2026.
- The last three Return on Sales figures came in at 0.18% (Q1 2026), 0.16% (Q4 2025), and 0.01% (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROS (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | - |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | 0.00% |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | 0.00% |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | - |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 0.00% |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | - |
| 10 | Zymeworks | 1.73 Bn | 1.36 Bn | - | -0.18% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -0.18% |
| Dec 31, 2025 | -0.16% |
| Sep 30, 2025 | -0.01% |
| Jun 30, 2025 | 0.00% |
| Mar 31, 2025 | -0.07% |
| Dec 31, 2024 | -0.01% |
| Sep 30, 2024 | -0.02% |
| Jun 30, 2024 | -0.05% |
| Mar 31, 2024 | -0.03% |
| Dec 31, 2023 | -0.01% |
| Sep 30, 2023 | -0.02% |
| Jun 30, 2023 | -0.07% |
| Mar 31, 2023 | -0.01% |
| Dec 31, 2022 | 0.01% |
| Sep 30, 2022 | -0.18% |
| Jun 30, 2022 | -0.12% |
| Mar 31, 2022 | -0.38% |
| Dec 31, 2021 | -0.05% |
| Sep 30, 2021 | -0.14% |