Zymeworks Inc. (NASDAQ:ZYME) showed up in the 13F filings of 203 institutional investors as of December 2025.
| Owner Name | Date | Shares Held | Change (QoQ) | Change (%) | Value (USD) |
|---|---|---|---|---|---|
| EcoR1 Capital, LLC | 31 Mar, 2026 | 22,970,388 | 0 | 0.00% | $575,178,516.00 |
| EcoR1 Capital, LLC | 31 Mar, 2026 | 22,970,388 | 0 | 0.00% | $604,810,316.00 |
| Rubric Capital Management LP | 31 Mar, 2026 | 7,000,000 | 1,250,000 | 21.74% | $175,280,000.00 |
| Rubric Capital Management LP | 31 Mar, 2026 | 5,750,000 | 1,039,449 | 22.07% | $151,397,500.00 |
| BlackRock, Inc. | 31 Mar, 2026 | 4,595,548 | 606,015 | 15.19% | $121,000,779.00 |
| BlackRock, Inc. | 31 Mar, 2026 | 4,553,888 | -41,660 | -0.91% | $114,029,354.00 |
| BVF INC/IL | 31 Mar, 2026 | 3,938,641 | 0 | 0.00% | $103,704,418.00 |
| BVF INC/IL | 31 Mar, 2026 | 3,734,142 | -204,499 | -5.19% | $93,502,916.00 |
| PERCEPTIVE ADVISORS LLC | 31 Mar, 2026 | 3,510,078 | 248,228 | 7.61% | $87,892,353.00 |
| PERCEPTIVE ADVISORS LLC | 31 Mar, 2026 | 3,261,850 | 1,171,187 | 56.02% | $85,884,511.00 |
| Morgan Stanley | 31 Mar, 2026 | 2,593,080 | -1,391,505 | -34.92% | $68,275,801.00 |
| Morgan Stanley | 31 Mar, 2026 | 2,480,568 | -112,512 | -4.34% | $62,113,426.00 |
| VANGUARD GROUP INC | 31 Mar, 2026 | 2,328,727 | 174,293 | 8.09% | $61,315,382.00 |
| BNP Paribas Asset Management Holding S.A. | 31 Mar, 2026 | 1,908,039 | 85,991 | 4.72% | $47,777,297.00 |
| BNP Paribas Asset Management Holding S.A. | 31 Mar, 2026 | 1,822,048 | 1,822,048 | 0.00% | $47,975.00 |
| VANGUARD CAPITAL MANAGEMENT LLC | 31 Mar, 2026 | 1,705,580 | 1,705,580 | 0.00% | $42,707,723.00 |
| Siren, L.L.C. | 31 Mar, 2026 | 1,680,121 | 1,680,121 | 0.00% | $44,237,586.00 |
| DEUTSCHE BANK AG\ | 31 Mar, 2026 | 1,595,833 | 50,935 | 3.30% | $42,018,282.00 |
| DIMENSIONAL FUND ADVISORS LP | 31 Mar, 2026 | 1,159,215 | -31,623 | -2.66% | $30,523,404.00 |
| CITADEL ADVISORS LLC | 31 Mar, 2026 | 1,150,018 | 894,667 | 350.37% | $28,796,451.00 |