Zymeworks ZYME Institutional Ownership

NASDAQ ZYME

$29.49 -0.41 (-1.37%)

As of: Sep 4, 2026 · 11:51 AM EDT

Institutions by Trading Activity

203 Institutions

Increased 88 43.3%

Unchanged 43 21.2%

Reduced 72 35.5%

Ownership Statistics

13F · as of 30 Jun, 2026

Institutional Ownership

93.77%

▲+0.38 pp QoQ

Shares Held by Institutions

68.45Mn

of 72.99Mn outstanding

▲+0.44% QoQ

Shares Outstanding

72.99Mn

4.55Mn held outside 13F filers

Institutional Investors

203

filed 13F for Jun 2026

▼-6 vs prior quarter

Net Shares Added (QoQ)

+299.53K

accumulated since last quarter

Value of Holdings

$2.05Bn

reported market value

Shares Owned by Institutions

Shares held % of outstanding

Latest —

Average ownership —

Peak ownership —

Shares Purchased/Sold by Institutions

Accumulated Distributed

Latest quarter —

Net over range —

Accumulating quarters —

Ownership Summary

Quarter ending 30 Jun, 2026

Zymeworks Inc. (NASDAQ:ZYME) appears in 203 institutional 13F filings for the quarter ending June 2026.

These investors held 93.8% of outstanding shares in June 2026, up from 93.4% in March 2026.
Their total shares held in ZYME increased 0.44% from the prior quarter, while the number of investors in Zymeworks increased 13.41% year over year.
During the quarter, 88 of these 203 funds increased positions in ZYME, 72 reduced exposure, and 43 held steady.
The aggregate institutional position in Zymeworks amounted to 68.45Mn shares as of June 2026, up by 299.53K shares quarter on quarter, and down 3.46Mn shares year over year.
As of June 30, 2026, EcoR1 Capital, LLC held the largest stake in Zymeworks with 22.97Mn shares, accounting for 31.47% of total shares outstanding.
The biggest buyers of Zymeworks for the quarter ending June 2026 included NOMURA ASSET MANAGEMENT INTERNATIONAL INC. (889.8K), Prosight Management, LP (674.43K), PERCEPTIVE ADVISORS LLC (672.88K), Assenagon Asset Management S.A. (524.04K), FIRST TRUST ADVISORS LP (340.36K).
The largest sales of ZYME for the quarter ending June 2026 came from Nuveen, LLC (532.27K), DEUTSCHE BANK AG\ (524.06K), Capricorn Fund Managers Ltd (520.68K), ARROWSTREET CAPITAL, LIMITED PARTNERSHIP (325.4K), BlackRock, Inc. (302.86K).
According to Business Quant data, leading holders of ZYME for June 2026 are EcoR1 Capital, LLC (22.97Mn), Rubric Capital Management LP (7.0Mn), BlackRock, Inc. (4.25Mn), PERCEPTIVE ADVISORS LLC (4.18Mn), BVF INC/IL (3.65Mn), Morgan Stanley (2.23Mn), BNP Paribas Asset Management Holding S.A. (1.78Mn), VANGUARD CAPITAL MANAGEMENT LLC (1.56Mn), Assenagon Asset Management S.A. (1.25Mn), Nextech Invest Ltd. (1.11Mn).

Form 13F Holdings

203 Institutional Holders

Report period 30 Jun, 2026

Total shares held 68.45Mn

Of outstanding 93.77%

#	Institution	CIK	Shares Held	% of Outstanding	Change (QoQ)	Change (%)	Value (USD)
1	EcoR1 Capital, LLC	0001587114	22,970,388	31.47%	0	0.00%	$600.45Mn
2	Rubric Capital Management LP	0001687509	7,000,000	9.59%	0	0.00%	$182.98Mn
3	BlackRock, Inc.	0002012383	4,251,030	5.82%	▼302,858	-6.65%	$111.12Mn
4	PERCEPTIVE ADVISORS LLC	0001224962	4,182,953	5.73%	▲672,875	+19.17%	$109.34Mn
5	BVF INC/IL	0001056807	3,649,142	5.00%	▼85,000	-2.28%	$95.39Mn
6	Morgan Stanley	0000895421	2,231,260	3.06%	▼249,308	-10.05%	$58.33Mn
7	BNP Paribas Asset Management Holding S.A.	0001520354	1,781,116	2.44%	▼126,923	-6.65%	$46.56Mn
8	VANGUARD CAPITAL MANAGEMENT LLC	0002100119	1,558,998	2.14%	▼146,582	-8.59%	$40.75Mn
9	Assenagon Asset Management S.A.	0001546007	1,252,027	1.72%	▲524,041	+71.99%	$32.73Mn
10	Nextech Invest Ltd.	0001595430	1,113,946	1.53%	0	0.00%	$29.12Mn
11	State Street Corp	0000093751	1,088,216	1.49%	▲76,439	+7.55%	$28.45Mn
12	DIMENSIONAL FUND ADVISORS LP	0000354204	994,955	1.36%	▼144,180	-12.66%	$26.00Mn
13	CITADEL ADVISORS LLC	0001423053	914,136	1.25%	▼235,882	-20.51%	$23.90Mn
14	NOMURA ASSET MANAGEMENT INTERNATIONAL INC.	0000921739	889,802	1.22%	▲889,802	0.00%	$23.26Mn
15	FMR LLC	0000315066	702,568	0.96%	▲35,415	+5.31%	$18.37Mn
16	GEODE CAPITAL MANAGEMENT, LLC	0001214717	692,410	0.95%	▲32,470	+4.92%	$18.10Mn
17	Prosight Management, LP	0001617201	674,434	0.92%	▲674,434	0.00%	$17.63Mn
18	Qube Research & Technologies Ltd	0001729829	593,590	0.81%	▲81,653	+15.95%	$15.52Mn
19	VANGUARD PORTFOLIO MANAGEMENT LLC	0002100121	510,032	0.70%	▲10,157	+2.03%	$13.33Mn
20	Redmile Group, LLC	0001425738	491,654	0.67%	0	0.00%	$12.85Mn

Showing 1 to 20 of 203 holders