Zymeworks (ZYME) Return on Capital Employed (2022 - 2026)

Zymeworks' (ZYME) quarterly Return on Capital Employed came in at 30.28% in Q1 2026, up 267.0% year-on-year from 8.25% in Q1 2025, and down 7.81% quarter-over-quarter from 28.08% in Q4 2025.

Zymeworks (ZYME) Return on Capital Employed (2022 - 2026) Analysis & Trends

Zymeworks has disclosed Return on Capital Employed across 5 years of filings, most recently posting 30.28% for Q1 2026.

  • Return on Capital Employed for Q1 2026 came in at 30.28%, up 267.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 30.28% (up 267.0% YoY), and the FY2025 annual result was 25.53%, up 608.0% from the prior year.
  • Return on Capital Employed came in at 30.28% for Q1 2026 at Zymeworks, down from 28.08% in the prior quarter.
  • In the past five years, Return on Capital Employed ranged from a high of 40.44% in Q3 2023 to a low of 35.44% in Q4 2024.
  • The 5-year median for Return on Capital Employed is 27.5% (2023), against an average of 10.18%.
  • Across the five-year window, Return on Capital Employed plunged 7357 bps in 2024 and surged 1356 bps in 2025, its largest moves.
  • Zymeworks' Return on Capital Employed stood at 34.45% in 2022, then plunged by 178 bps to 26.92% in 2023, then sank by 32 bps to 35.44% in 2024, then gained by 21 bps to 28.08% in 2025, then dropped by 8 bps to 30.28% in 2026.
  • The last three Return on Capital Employed figures came in at 30.28% (Q1 2026), 28.08% (Q4 2025), and 19.57% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROCE (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - 450.31%
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 51.73%
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -107.40%
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 21.10%
9 Abivax 91.96 Bn 91.96 Bn - -50.43%
10 Zymeworks 1.73 Bn 1.36 Bn - -30.28%

Historic Data

Download Data
DateValue
Mar 31, 2026 -30.28%
Dec 31, 2025 -28.08%
Sep 30, 2025 -19.57%
Jun 30, 2025 -21.85%
Mar 31, 2025 -32.94%
Dec 31, 2024 -35.44%
Sep 30, 2024 -33.13%
Jun 30, 2024 -28.61%
Mar 31, 2024 -29.11%
Dec 31, 2023 -26.92%
Sep 30, 2023 40.44%
Jun 30, 2023 36.95%
Mar 31, 2023 31.56%
Dec 31, 2022 34.45%