Zymeworks (ZYME) Net Margin (2021 - 2026)
Zymeworks' Net Margin came in at -980.81% for Q2 2026, down 985.56 percentage points from 4.76% a year earlier but up 853.16 percentage points from the prior quarter.
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Analysis
Zymeworks (ZYME) Net Margin (2021 - 2026) Analysis & Trends
Over the trailing twelve months to Jun 30, 2026, Zymeworks reported Net Margin of -404.00%, down 344.03 percentage points year-over-year; for FY2025, it was -76.56%, up 84.23 percentage points from FY2024.
- Net Margin carries a five-year change of +386.97 percentage points (FY2020 to FY2025).
- Going back by year, Net Margin was -160.80% in FY2024 (-4.67 pp), -156.13% in FY2023 (-186.27 pp), 30.14% in FY2022 (+824.16 pp) and -794.01% in FY2021 (-330.48 pp).
- The five-year range for quarterly Net Margin is -3790.45% (Q1 2022) to 76.88% (Q4 2022).
- Year-over-year, Net Margin has declined for three consecutive quarters, with an average year-over-year change of -469.19 percentage points over the last eight quarters.
- The fastest year-over-year change in Net Margin over five years came in Q1 2023 (a gain of 3722.00 percentage points), and the weakest in Q1 2026 (a drop of 1750.47 percentage points).
- Business Quant data shows ZYME's Net Margin at -1833.97% (Q1 2026), -1638.53% (Q4 2025) and -70.99% (Q3 2025) in the three quarters before Q2 2026.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,348.13 Bn | 1,321.74 Bn | 20.46 Bn | 26.44% |
| 2 | Johnson & Johnson | 675.90 Bn | 595.76 Bn | 17.30 Bn | 0.83% |
| 3 | AbbVie | 519.45 Bn | 487.50 Bn | 13.12 Bn | 24.24% |
| 4 | Merck | 364.95 Bn | 327.95 Bn | 13.19 Bn | 28.01% |
| 5 | Novartis Ag | 311.58 Bn | 285.16 Bn | - | - |
| 6 | Astrazeneca | 289.34 Bn | 262.94 Bn | 13.26 Bn | 20.69% |
| 7 | Amgen | 251.64 Bn | 203.30 Bn | 7.58 Bn | 37.28% |
| 8 | Gilead Sciences | 212.05 Bn | 187.07 Bn | 6.73 Bn | 29.27% |
| 9 | Pfizer | 167.35 Bn | 115.00 Bn | 12.56 Bn | 19.55% |
| 10 | Zymeworks | 2.24 Bn | 1.27 Bn | - | 67.73% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Sep 30, 2026 | 67.73% |
| Jun 30, 2026 | -980.81% |
| Mar 31, 2026 | -1,833.97% |
| Dec 31, 2025 | -1,638.53% |
| Sep 30, 2025 | -70.99% |
| Jun 30, 2025 | 4.76% |
| Mar 31, 2025 | -83.50% |
| Dec 31, 2024 | -75.75% |
| Sep 30, 2024 | -186.56% |
| Jun 30, 2024 | -195.84% |
| Mar 31, 2024 | -315.58% |
| Dec 31, 2023 | -85.56% |
| Sep 30, 2023 | -173.80% |
| Jun 30, 2023 | -730.53% |
| Mar 31, 2023 | -68.45% |
| Dec 31, 2022 | 76.88% |
| Sep 30, 2022 | -1,818.55% |
| Jun 30, 2022 | -1,187.41% |
| Mar 31, 2022 | -3,790.45% |
| Dec 31, 2021 | -197.04% |
API Access
Zymeworks Net Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=net-margin&ticker=ZYME&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "net-margin", "ticker": "ZYME", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=net-margin&ticker=ZYME&period=max&api_key=YOUR_API_KEY");
const data = await res.json();