Zymeworks (ZYME) Net Margin (2021 - 2026)

Zymeworks (ZYME) reported Net Margin of 1833.97% for Q1 2026, down 175047.0% on a YoY basis from N/an in Q1 2025, and down 11.93% sequentially from 1638.53% in Q4 2025.

Zymeworks (ZYME) Net Margin (2021 - 2026) Analysis & Trends

Zymeworks (ZYME) has 6 years of Net Margin data on file, last reported at 1833.97% in Q1 2026.

  • For the quarter ending Q1 2026, Net Margin fell 175047.0% year-over-year to 1833.97%; the trailing twelve-month figure through Mar 2026 stood at 126.33% (down 459.0% YoY), and the FY2025 full-year result was 76.56%, up 8423.0% from the prior year.
  • Net Margin slipped to 1833.97% in Q1 2026, from 1638.53% in the prior quarter.
  • In the past five years, Net Margin ranged from a high of 95.21% in Q4 2022 to a low of 3790.45% in Q1 2022.
  • A 5-year average of 715.03% and a median of 186.56% in 2024 frame the typical range for Net Margin.
  • Across the five-year window, Net Margin surged 372200 bps in 2023 and sank 175047 bps in 2026, its largest moves.
  • Tracing ZYME's Net Margin over 5 years: stood at 95.21% in 2022, then slumped by 190 bps to 85.56% in 2023, then gained by 11 bps to 75.75% in 2024, then plunged by 2063 bps to 1638.53% in 2025, then slipped by 12 bps to 1833.97% in 2026.
  • Business Quant data shows ZYME's Net Margin at 1833.97% in Q1 2026, 1638.53% in Q4 2025, and 70.99% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Margin (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 15.02%
4 NuCana 279.75 Bn 279.75 Bn - -
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 34.53%
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 20.17%
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 30.33%
9 Revolution Medicines 37.78 Bn 37.78 Bn - -
10 Zymeworks 1.73 Bn 1.36 Bn - -1,833.97%

Historic Data

Download Data
DateValue
Mar 31, 2026 -1,833.97%
Dec 31, 2025 -1,638.53%
Sep 30, 2025 -70.99%
Jun 30, 2025 4.76%
Mar 31, 2025 -83.50%
Dec 31, 2024 -75.75%
Sep 30, 2024 -186.56%
Jun 30, 2024 -195.84%
Mar 31, 2024 -315.58%
Dec 31, 2023 -85.56%
Sep 30, 2023 -173.80%
Jun 30, 2023 -730.53%
Mar 31, 2023 -68.45%
Dec 31, 2022 95.21%
Sep 30, 2022 -1,818.55%
Jun 30, 2022 -1,187.41%
Mar 31, 2022 -3,790.45%
Dec 31, 2021 -489.40%
Sep 30, 2021 -1,378.36%