Zymeworks (ZYME) Net Margin (2021 - 2026)

Zymeworks' (ZYME) quarterly Net Margin came in at 1833.97% in Q1 2026, down 110378.0% year-on-year from N/an in Q1 2025, and down 11.93% quarter-over-quarter from 1638.53% in Q4 2025.

Zymeworks (ZYME) Net Margin (2021 - 2026) Analysis & Trends

Zymeworks has disclosed Net Margin across 6 years of filings, most recently posting 1833.97% for Q1 2026.

  • Net Margin for Q1 2026 came in at 1833.97%, down 110378.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 130.52% (up 6503.0% YoY), and the FY2025 annual result was 76.56%, up 8423.0% from the prior year.
  • Net Margin came in at 1833.97% for Q1 2026 at Zymeworks, down from 1638.53% in the prior quarter.
  • In the past five years, Net Margin ranged from a high of 95.21% in Q4 2022 to a low of 3790.45% in Q1 2022.
  • The 5-year median for Net Margin is 315.58% (2024), against an average of 769.7%.
  • Across the five-year window, Net Margin surged 372200 bps in 2023 and slumped 156278 bps in 2025, its largest moves.
  • Zymeworks' Net Margin stood at 95.21% in 2022, then sank by 190 bps to 85.56% in 2023, then advanced by 11 bps to 75.75% in 2024, then tumbled by 2063 bps to 1638.53% in 2025, then dropped by 12 bps to 1833.97% in 2026.
  • The last three Net Margin figures came in at 1833.97% (Q1 2026), 1638.53% (Q4 2025), and 78.41% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Margin (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 0.82%
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 34.53%
9 Abivax 91.96 Bn 91.96 Bn - -
10 Zymeworks 1.73 Bn 1.36 Bn - -1,833.97%

Historic Data

Download Data
DateValue
Mar 31, 2026 -1,833.97%
Dec 31, 2025 -1,638.53%
Sep 30, 2025 -78.41%
Jun 30, 2025 4.76%
Mar 31, 2025 -730.19%
Dec 31, 2024 -75.75%
Sep 30, 2024 -186.56%
Jun 30, 2024 -471.08%
Mar 31, 2024 -315.58%
Dec 31, 2023 -85.56%
Sep 30, 2023 -173.80%
Jun 30, 2023 -730.53%
Mar 31, 2023 -68.45%
Dec 31, 2022 95.21%
Sep 30, 2022 -1,818.55%
Jun 30, 2022 -1,187.41%
Mar 31, 2022 -3,790.45%
Dec 31, 2021 -489.40%
Sep 30, 2021 -1,378.36%