Zymeworks (ZYME) Net Margin (2021 - 2026)
Zymeworks (ZYME) posted Net Margin of 1833.97% for Q1 2026, down 11.93% sequentially from 1638.53% in Q4 2025, and down 175047.0% YoY from N/an in Q1 2025.
Zymeworks (ZYME) Net Margin (2021 - 2026) Analysis & Trends
Zymeworks has reported Net Margin for 6 years, with the latest figure at 1833.97% in Q1 2026.
- Quarterly Net Margin fell 175047.0% year-over-year to 1833.97% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 126.33% (down 459.0% YoY) and the FY2025 annual result came in at 76.56%, up 8423.0% from the prior year.
- Net Margin slipped to 1833.97% in Q1 2026 per ZYME's latest filing, from 1638.53% in the prior quarter.
- Over five years, Net Margin peaked at 95.21% in Q4 2022 and troughed at 3790.45% in Q1 2022.
- A 5-year average of 715.03% and a median of 186.56% in 2024 frame the typical range for Net Margin.
- The sharpest annual moves came in 2023 and 2026: Net Margin jumped 372200 bps in 2023, then tumbled 175047 bps in 2026.
- Over 5 years, Net Margin stood at 95.21% in 2022, then sank by 190 bps to 85.56% in 2023, then grew by 11 bps to 75.75% in 2024, then tumbled by 2063 bps to 1638.53% in 2025, then fell by 12 bps to 1833.97% in 2026.
- According to Business Quant data, Net Margin over the past three periods registered 1833.97%, 1638.53%, and 70.99% for Q1 2026, Q4 2025, and Q3 2025 respectively.
Powered by 
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 128.13 Bn | 120.28 Bn | 2.84 Bn | 32.99% |
| 2 | Regeneron Pharmaceuticals | 112.33 Bn | 104.33 Bn | 3.93 Bn | 30.23% |
| 3 | Argenx Se | 53.24 Bn | 48.05 Bn | 1.41 Bn | 30.33% |
| 4 | Revolution Medicines | 43.64 Bn | 43.64 Bn | - | - |
| 5 | BeOne Medicines | 39.27 Bn | 34.17 Bn | 1.53 Bn | 13.90% |
| 6 | MindWalk Holdings | 35.32 Bn | 35.31 Bn | 1.82 Bn | 30.98% |
| 7 | Royalty Pharma | 33.72 Bn | 35.84 Bn | - | 12.09% |
| 8 | Alnylam Pharmaceuticals | 30.58 Bn | 27.27 Bn | 992.69 Mn | 12.74% |
| 9 | Insmed | 27.01 Bn | 25.85 Bn | 358.27 Mn | -3.12% |
| 10 | Zymeworks | 1.79 Bn | 1.52 Bn | - | -980.81% |
Historic Data
Download Data| Date | Value |
|---|---|
| Jun 30, 2026 | -980.81% |
| Mar 31, 2026 | -1,833.97% |
| Dec 31, 2025 | -1,638.53% |
| Sep 30, 2025 | -70.99% |
| Jun 30, 2025 | 4.76% |
| Mar 31, 2025 | -83.50% |
| Dec 31, 2024 | -75.75% |
| Sep 30, 2024 | -186.56% |
| Jun 30, 2024 | -195.84% |
| Mar 31, 2024 | -315.58% |
| Dec 31, 2023 | -85.56% |
| Sep 30, 2023 | -173.80% |
| Jun 30, 2023 | -730.53% |
| Mar 31, 2023 | -68.45% |
| Dec 31, 2022 | 95.21% |
| Sep 30, 2022 | -1,818.55% |
| Jun 30, 2022 | -1,187.41% |
| Mar 31, 2022 | -3,790.45% |
| Dec 31, 2021 | -489.40% |
| Sep 30, 2021 | -1,378.36% |