Zymeworks (ZYME) Net Margin (2021 - 2026)
Zymeworks recorded quarterly Net Margin of 1833.97% in Q1 2026, down 11.93% quarter-over-quarter from 1638.53% in Q4 2025, and down 110378.0% year-over-year from N/an in Q1 2025.
Zymeworks' Net Margin history runs 6 years deep, the most recent figure standing at 1833.97% for Q1 2026.
- In Q1 2026, Net Margin fell 110378.0% year-over-year to 1833.97%; the TTM figure through Mar 2026 stood at 130.52% (up 6503.0% YoY), while the FY2025 annual figure was 76.56%, up 8423.0% from the prior year.
- Net Margin came in at 1833.97% for Q1 2026 at Zymeworks, down from 1638.53% in the prior quarter.
- In the past five years, Net Margin ranged from a high of 95.21% in Q4 2022 to a low of 3790.45% in Q1 2022.
- A 5-year average of 769.7% and a median of 315.58% in 2024 frame the typical range for Net Margin.
- Across the five-year window, Net Margin soared 372200 bps in 2023 and sank 156278 bps in 2025, its largest moves.
- Zymeworks' Net Margin stood at 95.21% in 2022, then plunged by 190 bps to 85.56% in 2023, then climbed by 11 bps to 75.75% in 2024, then slumped by 2063 bps to 1638.53% in 2025, then declined by 12 bps to 1833.97% in 2026.
- According to Business Quant data, Net Margin over the past three periods registered 1833.97%, 1638.53%, and 78.41% for Q1 2026, Q4 2025, and Q3 2025 respectively.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 961,148.99 Bn | 961,148.98 Bn | - | - |
| 2 | Alterity Therapeutics | 744,933.29 Bn | 744,933.26 Bn | - | - |
| 3 | Legend Biotech | 2,540.00 Bn | 2,539.71 Bn | 242.10 Mn | 0.82% |
| 4 | Nanobiotix | 2,199.85 Bn | 2,199.78 Bn | - | - |
| 5 | Akari Therapeutics | 1,635.88 Bn | 1,635.88 Bn | - | - |
| 6 | Vertex Pharmaceuticals | 111.32 Bn | 104.07 Bn | 2.59 Bn | 34.53% |
| 7 | Evaxion A | 62.56 Bn | 62.54 Bn | - | - |
| 8 | Regeneron Pharmaceuticals | 62.55 Bn | 53.79 Bn | 3.31 Bn | 20.17% |
| 9 | Alnylam Pharmaceuticals | 39.57 Bn | 36.56 Bn | 959.66 Mn | 17.65% |
| 10 | Zymeworks | 1.84 Bn | 1.47 Bn | - | -1,833.97% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -1,833.97% |
| Dec 31, 2025 | -1,638.53% |
| Sep 30, 2025 | -78.41% |
| Jun 30, 2025 | 4.76% |
| Mar 31, 2025 | -730.19% |
| Dec 31, 2024 | -75.75% |
| Sep 30, 2024 | -186.56% |
| Jun 30, 2024 | -471.08% |
| Mar 31, 2024 | -315.58% |
| Dec 31, 2023 | -85.56% |
| Sep 30, 2023 | -173.80% |
| Jun 30, 2023 | -730.53% |
| Mar 31, 2023 | -68.45% |
| Dec 31, 2022 | 95.21% |
| Sep 30, 2022 | -1,818.55% |
| Jun 30, 2022 | -1,187.41% |
| Mar 31, 2022 | -3,790.45% |
| Dec 31, 2021 | -489.40% |
| Sep 30, 2021 | -1,378.36% |