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Cash Flow Statement
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Zymeworks (ZYME) Net Cash Flow (2021 - 2025)

Zymeworks' Net Cash Flow history spans 5 years, with the latest figure at -$23.6 million for Q4 2025.

  • On a quarterly basis, Net Cash Flow rose 58.07% to -$23.6 million in Q4 2025 year-over-year; TTM through Dec 2025 was -$24.9 million, a 72.86% increase, with the full-year FY2025 number at -$24.9 million, up 72.86% from a year prior.
  • Net Cash Flow hit -$23.6 million in Q4 2025 for Zymeworks, up from -$33.5 million in the prior quarter.
  • Over the last five years, Net Cash Flow for ZYME hit a ceiling of $304.9 million in Q4 2022 and a floor of -$219.7 million in Q1 2023.
  • Historically, Net Cash Flow has averaged -$12.5 million across 5 years, with a median of -$39.5 million in 2023.
  • Biggest five-year swings in Net Cash Flow: surged 690.05% in 2022 and later crashed 397.78% in 2023.
  • Tracing ZYME's Net Cash Flow over 5 years: stood at -$51.7 million in 2021, then surged by 690.05% to $304.9 million in 2022, then plummeted by 79.26% to $63.2 million in 2023, then plummeted by 189.15% to -$56.4 million in 2024, then soared by 58.07% to -$23.6 million in 2025.
  • Business Quant data shows Net Cash Flow for ZYME at -$23.6 million in Q4 2025, -$33.5 million in Q3 2025, and $22.1 million in Q2 2025.