Zymeworks (ZYME) Net Cash Flow (2021 - 2026)

Zymeworks' (ZYME) quarterly Net Cash Flow came in at $203.0 million in Q1 2026, up 1911.96% year-on-year from $10.1 million in Q1 2025, and up 959.08% quarter-over-quarter from -$23.6 million in Q4 2025.

Zymeworks (ZYME) Net Cash Flow (2021 - 2026) Analysis & Trends

Zymeworks has disclosed Net Cash Flow across 6 years of filings, most recently posting $203.0 million for Q1 2026.

  • Net Cash Flow for Q1 2026 came in at $203.0 million, up 1911.96% year-over-year; the trailing twelve-month figure through Mar 2026 was $168.0 million (up 533.23% YoY), and the FY2025 annual result was -$24.9 million, up 72.86% from the prior year.
  • Net Cash Flow came in at $203.0 million for Q1 2026 at Zymeworks, up from -$23.6 million in the prior quarter.
  • In the past five years, Net Cash Flow ranged from a high of $304.9 million in Q4 2022 to a low of -$219.7 million in Q1 2023.
  • The 5-year median for Net Cash Flow is -$33.5 million (2025), against an average of $2.4 million.
  • Across the five-year window, Net Cash Flow tumbled 397.78% in 2023 and jumped 1911.96% in 2026, its largest moves.
  • Zymeworks' Net Cash Flow stood at $304.9 million in 2022, then tumbled by 79.26% to $63.2 million in 2023, then plunged by 189.15% to -$56.4 million in 2024, then surged by 58.07% to -$23.6 million in 2025, then jumped by 959.08% to $203.0 million in 2026.
  • The last three Net Cash Flow figures came in at $203.0 million (Q1 2026), -$23.6 million (Q4 2025), and -$33.5 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Cash Flow (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - 2.44 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 625.70 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -2.44 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 457.40 Mn
9 Abivax 91.96 Bn 91.96 Bn - 664,983.53
10 Zymeworks 1.73 Bn 1.36 Bn - 203.03 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 203.03 Mn
Mar 31, 2026 203.03 Mn
Dec 31, 2025 -23.63 Mn
Dec 31, 2025 -23.63 Mn
Sep 30, 2025 -33.50 Mn
Sep 30, 2025 -33.50 Mn
Jun 30, 2025 22.14 Mn
Jun 30, 2025 22.14 Mn
Mar 31, 2025 10.09 Mn
Mar 31, 2025 10.09 Mn
Dec 31, 2024 -56.37 Mn
Dec 31, 2024 -56.37 Mn
Sep 30, 2024 51.40 Mn
Sep 30, 2024 51.40 Mn
Jun 30, 2024 -43.91 Mn
Jun 30, 2024 -43.91 Mn
Mar 31, 2024 -42.86 Mn
Mar 31, 2024 -42.86 Mn
Dec 31, 2023 63.23 Mn
Dec 31, 2023 63.23 Mn