Zymeworks (ZYME) Net Cash Flow (2021 - 2026)

Zymeworks (ZYME) reported Net Cash Flow of $203.0 million for Q1 2026, up 1911.96% on a YoY basis from $10.1 million in Q1 2025, and up 959.08% sequentially from -$23.6 million in Q4 2025.

Zymeworks (ZYME) Net Cash Flow (2021 - 2026) Analysis & Trends

Zymeworks (ZYME) has 6 years of Net Cash Flow data on file, last reported at $203.0 million in Q1 2026.

  • For the quarter ending Q1 2026, Net Cash Flow rose 1911.96% year-over-year to $203.0 million; the trailing twelve-month figure through Mar 2026 stood at $168.0 million (up 533.23% YoY), and the FY2025 full-year result was -$24.9 million, up 72.86% from the prior year.
  • Net Cash Flow grew to $203.0 million in Q1 2026, from -$23.6 million in the prior quarter.
  • In the past five years, Net Cash Flow ranged from a high of $304.9 million in Q4 2022 to a low of -$219.7 million in Q1 2023.
  • A 5-year average of $2.4 million and a median of -$33.5 million in 2025 frame the typical range for Net Cash Flow.
  • Across the five-year window, Net Cash Flow sank 397.78% in 2023 and jumped 1911.96% in 2026, its largest moves.
  • Tracing ZYME's Net Cash Flow over 5 years: stood at $304.9 million in 2022, then plunged by 79.26% to $63.2 million in 2023, then sank by 189.15% to -$56.4 million in 2024, then jumped by 58.07% to -$23.6 million in 2025, then soared by 959.08% to $203.0 million in 2026.
  • Business Quant data shows ZYME's Net Cash Flow at $203.0 million in Q1 2026, -$23.6 million in Q4 2025, and -$33.5 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Cash Flow (Qtr)
1 Oculis Holding AG 66,621.14 Bn 66,620.85 Bn - 10.56 Mn
2 Nanobiotix 1,915.18 Bn 1,915.11 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -2.44 Mn
4 BeOne Medicines 471.27 Bn 466.48 Bn 1.35 Bn 224.46 Mn
5 Vertex Pharmaceuticals 121.81 Bn 114.57 Bn 2.59 Bn 457.40 Mn
6 Regeneron Pharmaceuticals 69.58 Bn 60.82 Bn 3.31 Bn -152.20 Mn
7 Belite Bio 62.72 Bn 62.72 Bn - -
8 Argenx Se 55.51 Bn 50.33 Bn 1.41 Bn -
9 Revolution Medicines 37.35 Bn 37.35 Bn - 57.19 Mn
10 Zymeworks 1.73 Bn 1.36 Bn - 203.03 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 203.03 Mn
Mar 31, 2026 203.03 Mn
Dec 31, 2025 -23.63 Mn
Dec 31, 2025 -23.63 Mn
Sep 30, 2025 -33.50 Mn
Sep 30, 2025 -33.50 Mn
Jun 30, 2025 22.14 Mn
Jun 30, 2025 22.14 Mn
Mar 31, 2025 10.09 Mn
Mar 31, 2025 10.09 Mn
Dec 31, 2024 -56.37 Mn
Dec 31, 2024 -56.37 Mn
Sep 30, 2024 51.40 Mn
Sep 30, 2024 51.40 Mn
Jun 30, 2024 -43.91 Mn
Jun 30, 2024 -43.91 Mn
Mar 31, 2024 -42.86 Mn
Mar 31, 2024 -42.86 Mn
Dec 31, 2023 63.23 Mn
Dec 31, 2023 63.23 Mn