Growth Metrics

Zymeworks (ZYME) Net Cash Flow (2021 - 2026)

Zymeworks recorded quarterly Net Cash Flow of $203.0 million in Q1 2026, up 959.08% quarter-over-quarter from -$23.6 million in Q4 2025, and up 1911.96% year-over-year from $10.1 million in Q1 2025.

Zymeworks' Net Cash Flow history runs 6 years deep, the most recent figure standing at $203.0 million for Q1 2026.

  • In Q1 2026, Net Cash Flow rose 1911.96% year-over-year to $203.0 million; the TTM figure through Mar 2026 stood at $168.0 million (up 533.23% YoY), while the FY2025 annual figure was -$24.9 million, up 72.86% from the prior year.
  • Net Cash Flow came in at $203.0 million for Q1 2026 at Zymeworks, up from -$23.6 million in the prior quarter.
  • In the past five years, Net Cash Flow ranged from a high of $304.9 million in Q4 2022 to a low of -$219.7 million in Q1 2023.
  • A 5-year average of $2.4 million and a median of -$33.5 million in 2025 frame the typical range for Net Cash Flow.
  • Across the five-year window, Net Cash Flow slumped 397.78% in 2023 and surged 1911.96% in 2026, its largest moves.
  • Zymeworks' Net Cash Flow stood at $304.9 million in 2022, then slumped by 79.26% to $63.2 million in 2023, then tumbled by 189.15% to -$56.4 million in 2024, then soared by 58.07% to -$23.6 million in 2025, then surged by 959.08% to $203.0 million in 2026.
  • According to Business Quant data, Net Cash Flow over the past three periods registered $203.0 million, -$23.6 million, and -$33.5 million for Q1 2026, Q4 2025, and Q3 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Cash Flow (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - 2.44 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn 625.70 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -2.44 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 457.40 Mn
7 Evaxion A 62.56 Bn 62.54 Bn - -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn -152.20 Mn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 60.68 Mn
10 Zymeworks 1.84 Bn 1.47 Bn - 203.03 Mn

Historic Data

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DateValue
Mar 31, 2026 203.03 Mn
Mar 31, 2026 203.03 Mn
Dec 31, 2025 -23.63 Mn
Dec 31, 2025 -23.63 Mn
Sep 30, 2025 -33.50 Mn
Sep 30, 2025 -33.50 Mn
Jun 30, 2025 22.14 Mn
Jun 30, 2025 22.14 Mn
Mar 31, 2025 10.09 Mn
Mar 31, 2025 10.09 Mn
Dec 31, 2024 -56.37 Mn
Dec 31, 2024 -56.37 Mn
Sep 30, 2024 51.40 Mn
Sep 30, 2024 51.40 Mn
Jun 30, 2024 -43.91 Mn
Jun 30, 2024 -43.91 Mn
Mar 31, 2024 -42.86 Mn
Mar 31, 2024 -42.86 Mn
Dec 31, 2023 63.23 Mn
Dec 31, 2023 63.23 Mn
Sep 30, 2023 -47.79 Mn
Sep 30, 2023 -47.79 Mn
Jun 30, 2023 -39.47 Mn
Jun 30, 2023 -39.47 Mn
Mar 31, 2023 -219.68 Mn
Mar 31, 2023 -219.68 Mn
Dec 31, 2022 304.92 Mn
Dec 31, 2022 304.92 Mn
Sep 30, 2022 -102.82 Mn
Sep 30, 2022 -102.82 Mn
Jun 30, 2022 -77.03 Mn
Jun 30, 2022 -77.03 Mn
Mar 31, 2022 73.77 Mn
Mar 31, 2022 73.77 Mn
Dec 31, 2021 -51.68 Mn
Dec 31, 2021 -51.68 Mn