Zymeworks (ZYME) Net Cash Flow (2021 - 2026)
Zymeworks' (ZYME) quarterly Net Cash Flow came in at $203.0 million in Q1 2026, up 1911.96% year-on-year from $10.1 million in Q1 2025, and up 959.08% quarter-over-quarter from -$23.6 million in Q4 2025.
Zymeworks (ZYME) Net Cash Flow (2021 - 2026) Analysis & Trends
Zymeworks has disclosed Net Cash Flow across 6 years of filings, most recently posting $203.0 million for Q1 2026.
- Net Cash Flow for Q1 2026 came in at $203.0 million, up 1911.96% year-over-year; the trailing twelve-month figure through Mar 2026 was $168.0 million (up 533.23% YoY), and the FY2025 annual result was -$24.9 million, up 72.86% from the prior year.
- Net Cash Flow came in at $203.0 million for Q1 2026 at Zymeworks, up from -$23.6 million in the prior quarter.
- In the past five years, Net Cash Flow ranged from a high of $304.9 million in Q4 2022 to a low of -$219.7 million in Q1 2023.
- The 5-year median for Net Cash Flow is -$33.5 million (2025), against an average of $2.4 million.
- Across the five-year window, Net Cash Flow tumbled 397.78% in 2023 and jumped 1911.96% in 2026, its largest moves.
- Zymeworks' Net Cash Flow stood at $304.9 million in 2022, then tumbled by 79.26% to $63.2 million in 2023, then plunged by 189.15% to -$56.4 million in 2024, then surged by 58.07% to -$23.6 million in 2025, then jumped by 959.08% to $203.0 million in 2026.
- The last three Net Cash Flow figures came in at $203.0 million (Q1 2026), -$23.6 million (Q4 2025), and -$33.5 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Cash Flow (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | 2.44 Mn |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | 625.70 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | -2.44 Mn |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 457.40 Mn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | 664,983.53 |
| 10 | Zymeworks | 1.73 Bn | 1.36 Bn | - | 203.03 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 203.03 Mn |
| Mar 31, 2026 | 203.03 Mn |
| Dec 31, 2025 | -23.63 Mn |
| Dec 31, 2025 | -23.63 Mn |
| Sep 30, 2025 | -33.50 Mn |
| Sep 30, 2025 | -33.50 Mn |
| Jun 30, 2025 | 22.14 Mn |
| Jun 30, 2025 | 22.14 Mn |
| Mar 31, 2025 | 10.09 Mn |
| Mar 31, 2025 | 10.09 Mn |
| Dec 31, 2024 | -56.37 Mn |
| Dec 31, 2024 | -56.37 Mn |
| Sep 30, 2024 | 51.40 Mn |
| Sep 30, 2024 | 51.40 Mn |
| Jun 30, 2024 | -43.91 Mn |
| Jun 30, 2024 | -43.91 Mn |
| Mar 31, 2024 | -42.86 Mn |
| Mar 31, 2024 | -42.86 Mn |
| Dec 31, 2023 | 63.23 Mn |
| Dec 31, 2023 | 63.23 Mn |