Zymeworks (ZYME) Free Cash Flow (2021 - 2026)
Zymeworks' (ZYME) quarterly Free Cash Flow came in at -$45.8 million in Q1 2026, down 1238.53% year-on-year from $4.0 million in Q1 2025, and down 391.66% quarter-over-quarter from -$9.3 million in Q4 2025.
Zymeworks (ZYME) Free Cash Flow (2021 - 2026) Analysis & Trends
Zymeworks has disclosed Free Cash Flow across 6 years of filings, most recently posting -$45.8 million for Q1 2026.
- Free Cash Flow for Q1 2026 came in at -$45.8 million, down 1238.53% year-over-year; the trailing twelve-month figure through Mar 2026 was -$75.4 million (up 0.54% YoY), and the FY2025 annual result was -$33.0 million, up 70.01% from the prior year.
- Free Cash Flow came in at -$45.8 million for Q1 2026 at Zymeworks, down from -$9.3 million in the prior quarter.
- In the past five years, Free Cash Flow ranged from a high of $320.6 million in Q4 2022 to a low of -$83.6 million in Q1 2023.
- The 5-year median for Free Cash Flow is -$31.8 million (2025), against an average of -$10.2 million.
- Across the five-year window, Free Cash Flow surged 679.9% in 2022 and sank 1238.53% in 2026, its largest moves.
- Zymeworks' Free Cash Flow stood at $320.6 million in 2022, then sank by 95.77% to $13.6 million in 2023, then tumbled by 393.39% to -$39.8 million in 2024, then surged by 76.6% to -$9.3 million in 2025, then tumbled by 391.66% to -$45.8 million in 2026.
- The last three Free Cash Flow figures came in at -$45.8 million (Q1 2026), -$9.3 million (Q4 2025), and -$31.8 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Free Cash Flow (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | -1.67 Mn |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -12.20 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | -2.49 Mn |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 1.29 Bn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | 63,220.27 |
| 10 | Zymeworks | 1.73 Bn | 1.36 Bn | - | -45.82 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -45.82 Mn |
| Mar 31, 2026 | -45.82 Mn |
| Dec 31, 2025 | -9.32 Mn |
| Dec 31, 2025 | -9.32 Mn |
| Sep 30, 2025 | -31.82 Mn |
| Sep 30, 2025 | -31.82 Mn |
| Jun 30, 2025 | 11.56 Mn |
| Jun 30, 2025 | 11.56 Mn |
| Mar 31, 2025 | -3.42 Mn |
| Mar 31, 2025 | -3.42 Mn |
| Dec 31, 2024 | -39.83 Mn |
| Dec 31, 2024 | -39.83 Mn |
| Sep 30, 2024 | -6.78 Mn |
| Sep 30, 2024 | -6.78 Mn |
| Jun 30, 2024 | -25.77 Mn |
| Jun 30, 2024 | -25.77 Mn |
| Mar 31, 2024 | -37.68 Mn |
| Mar 31, 2024 | -37.68 Mn |
| Dec 31, 2023 | 13.58 Mn |
| Dec 31, 2023 | 13.58 Mn |