Zymeworks (ZYME) Free Cash Flow (2021 - 2026)

Zymeworks (ZYME) reported Free Cash Flow of -$45.8 million for Q1 2026, down 1238.53% on a YoY basis from $4.0 million in Q1 2025, and down 322.68% sequentially from -$10.8 million in Q4 2025.

Zymeworks (ZYME) Free Cash Flow (2021 - 2026) Analysis & Trends

Zymeworks (ZYME) has 6 years of Free Cash Flow data on file, last reported at -$45.8 million in Q1 2026.

  • For the quarter ending Q1 2026, Free Cash Flow fell 1238.53% year-over-year to -$45.8 million; the trailing twelve-month figure through Mar 2026 stood at -$76.9 million (up 1.13% YoY), and the FY2025 full-year result was -$34.5 million, up 69.19% from the prior year.
  • Free Cash Flow fell to -$45.8 million in Q1 2026, from -$10.8 million in the prior quarter.
  • In the past five years, Free Cash Flow ranged from a high of $327.8 million in Q4 2022 to a low of -$83.6 million in Q1 2023.
  • A 5-year average of -$9.9 million and a median of -$31.8 million in 2025 frame the typical range for Free Cash Flow.
  • Across the five-year window, Free Cash Flow surged 745.43% in 2022 and tumbled 1238.53% in 2026, its largest moves.
  • Tracing ZYME's Free Cash Flow over 5 years: stood at $327.8 million in 2022, then slumped by 95.14% to $15.9 million in 2023, then tumbled by 362.57% to -$41.8 million in 2024, then surged by 74.08% to -$10.8 million in 2025, then slumped by 322.68% to -$45.8 million in 2026.
  • Business Quant data shows ZYME's Free Cash Flow at -$45.8 million in Q1 2026, -$10.8 million in Q4 2025, and -$31.8 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Free Cash Flow (Qtr)
1 Oculis Holding AG 66,621.14 Bn 66,620.85 Bn - -19.58 Mn
2 Nanobiotix 1,915.18 Bn 1,915.11 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -2.49 Mn
4 BeOne Medicines 471.27 Bn 466.48 Bn 1.35 Bn 158.09 Mn
5 Vertex Pharmaceuticals 121.81 Bn 114.57 Bn 2.59 Bn 1.29 Bn
6 Regeneron Pharmaceuticals 69.58 Bn 60.82 Bn 3.31 Bn 848.30 Mn
7 Belite Bio 62.72 Bn 62.72 Bn - -
8 Argenx Se 55.51 Bn 50.33 Bn 1.41 Bn -
9 Revolution Medicines 37.35 Bn 37.35 Bn - -354.95 Mn
10 Zymeworks 1.73 Bn 1.36 Bn - -45.82 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -45.82 Mn
Mar 31, 2026 -45.82 Mn
Dec 31, 2025 -10.84 Mn
Dec 31, 2025 -10.84 Mn
Sep 30, 2025 -31.82 Mn
Sep 30, 2025 -31.82 Mn
Jun 30, 2025 11.56 Mn
Jun 30, 2025 11.56 Mn
Mar 31, 2025 -3.42 Mn
Mar 31, 2025 -3.42 Mn
Dec 31, 2024 -41.82 Mn
Dec 31, 2024 -41.82 Mn
Sep 30, 2024 -6.78 Mn
Sep 30, 2024 -6.78 Mn
Jun 30, 2024 -25.77 Mn
Jun 30, 2024 -25.77 Mn
Mar 31, 2024 -37.68 Mn
Mar 31, 2024 -37.68 Mn
Dec 31, 2023 15.93 Mn
Dec 31, 2023 15.93 Mn