Growth Metrics

Zymeworks (ZYME) Enterprise Value (2021 - 2026)

Zymeworks recorded quarterly Enterprise Value of -$364.7 million in Q1 2026, down 59.41% quarter-over-quarter from -$228.8 million in Q4 2025, and down 37.48% year-over-year from -$583.4 million in Q1 2025.

Zymeworks' Enterprise Value history runs 6 years deep, the most recent figure standing at -$364.7 million for Q1 2026.

  • In Q1 2026, Enterprise Value fell 37.48% year-over-year to -$364.7 million; the TTM figure through Mar 2026 stood at -$364.7 million (down 37.48% YoY), while the FY2025 annual figure was -$228.8 million, down 1.34% from the prior year.
  • Enterprise Value came in at -$364.7 million for Q1 2026 at Zymeworks, down from -$228.8 million in the prior quarter.
  • In the past five years, Enterprise Value ranged from a high of -$166.2 million in Q3 2022 to a low of -$492.2 million in Q4 2022.
  • A 5-year average of -$306.6 million and a median of -$297.2 million in 2024 frame the typical range for Enterprise Value.
  • Across the five-year window, Enterprise Value tumbled 94.86% in 2022 and soared 39.68% in 2024, its largest moves.
  • Zymeworks' Enterprise Value stood at -$492.2 million in 2022, then advanced by 23.95% to -$374.3 million in 2023, then surged by 39.68% to -$225.8 million in 2024, then fell by 1.34% to -$228.8 million in 2025, then tumbled by 59.41% to -$364.7 million in 2026.
  • According to Business Quant data, Enterprise Value over the past three periods registered -$364.7 million, -$228.8 million, and -$251.9 million for Q1 2026, Q4 2025, and Q3 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Enterprise Value (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -2.32 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -32.30 Mn
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -286.70 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -61.46 Mn
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -2.77 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn -7.25 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - -18.44 Mn
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn -8.75 Bn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn -3.01 Bn
10 Zymeworks 1.84 Bn 1.47 Bn - -364.73 Mn

Historic Data

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DateValue
Mar 31, 2026 -364.73 Mn
Dec 31, 2025 -228.80 Mn
Sep 30, 2025 -251.93 Mn
Jun 30, 2025 -281.38 Mn
Mar 31, 2025 -265.29 Mn
Dec 31, 2024 -225.78 Mn
Sep 30, 2024 -297.20 Mn
Jun 30, 2024 -330.15 Mn
Mar 31, 2024 -345.05 Mn
Dec 31, 2023 -374.33 Mn
Sep 30, 2023 -295.41 Mn
Jun 30, 2023 -340.09 Mn
Mar 31, 2023 -340.79 Mn
Dec 31, 2022 -492.23 Mn
Sep 30, 2022 -166.24 Mn
Dec 31, 2021 -252.61 Mn