Zymeworks (ZYME) Enterprise Value (2021 - 2026)

Zymeworks' (ZYME) quarterly Enterprise Value came in at -$364.7 million in Q1 2026, down 37.48% year-on-year from -$583.4 million in Q1 2025, and down 59.41% quarter-over-quarter from -$228.8 million in Q4 2025.

Zymeworks (ZYME) Enterprise Value (2021 - 2026) Analysis & Trends

Zymeworks has disclosed Enterprise Value across 6 years of filings, most recently posting -$364.7 million for Q1 2026.

  • Enterprise Value for Q1 2026 came in at -$364.7 million, down 37.48% year-over-year; the trailing twelve-month figure through Mar 2026 was -$364.7 million (down 37.48% YoY), and the FY2025 annual result was -$228.8 million, down 1.34% from the prior year.
  • Enterprise Value came in at -$364.7 million for Q1 2026 at Zymeworks, down from -$228.8 million in the prior quarter.
  • In the past five years, Enterprise Value ranged from a high of -$166.2 million in Q3 2022 to a low of -$492.2 million in Q4 2022.
  • The 5-year median for Enterprise Value is -$297.2 million (2024), against an average of -$306.6 million.
  • Across the five-year window, Enterprise Value plunged 94.86% in 2022 and surged 39.68% in 2024, its largest moves.
  • Zymeworks' Enterprise Value stood at -$492.2 million in 2022, then gained by 23.95% to -$374.3 million in 2023, then jumped by 39.68% to -$225.8 million in 2024, then declined by 1.34% to -$228.8 million in 2025, then plunged by 59.41% to -$364.7 million in 2026.
  • The last three Enterprise Value figures came in at -$364.7 million (Q1 2026), -$228.8 million (Q4 2025), and -$251.9 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Enterprise Value (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -32.30 Mn
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -4.14 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -286.70 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -18.44 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -2.77 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -7.20 Mn
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn -7.25 Bn
9 Abivax 91.96 Bn 91.96 Bn - -584.73 Mn
10 Zymeworks 1.73 Bn 1.36 Bn - -364.73 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -364.73 Mn
Dec 31, 2025 -228.80 Mn
Sep 30, 2025 -251.93 Mn
Jun 30, 2025 -281.38 Mn
Mar 31, 2025 -265.29 Mn
Dec 31, 2024 -225.78 Mn
Sep 30, 2024 -297.20 Mn
Jun 30, 2024 -330.15 Mn
Mar 31, 2024 -345.05 Mn
Dec 31, 2023 -374.33 Mn
Sep 30, 2023 -295.41 Mn
Jun 30, 2023 -340.09 Mn
Mar 31, 2023 -340.79 Mn
Dec 31, 2022 -492.23 Mn
Sep 30, 2022 -166.24 Mn
Dec 31, 2021 -252.61 Mn