Zymeworks (ZYME) Enterprise Value (2021 - 2026)
Zymeworks (ZYME) posted Enterprise Value of -$364.7 million for Q1 2026, down 59.41% sequentially from -$228.8 million in Q4 2025, and down 37.48% YoY from -$583.4 million in Q1 2025.
Analysis
Zymeworks (ZYME) Enterprise Value (2021 - 2026) Analysis & Trends
Zymeworks has reported Enterprise Value for 6 years, with the latest figure at -$364.7 million in Q1 2026.
- Quarterly Enterprise Value fell 37.48% year-over-year to -$364.7 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$364.7 million (down 37.48% YoY) and the FY2025 annual result came in at -$228.8 million, down 1.34% from the prior year.
- Enterprise Value eased to -$364.7 million in Q1 2026 per ZYME's latest filing, from -$228.8 million in the prior quarter.
- Over five years, Enterprise Value peaked at -$166.2 million in Q3 2022 and troughed at -$492.2 million in Q4 2022.
- A 5-year average of -$306.6 million and a median of -$297.2 million in 2024 frame the typical range for Enterprise Value.
- The sharpest annual moves came in 2022 and 2024: Enterprise Value plunged 94.86% in 2022, then jumped 39.68% in 2024.
- Over 5 years, Enterprise Value stood at -$492.2 million in 2022, then climbed by 23.95% to -$374.3 million in 2023, then soared by 39.68% to -$225.8 million in 2024, then retreated by 1.34% to -$228.8 million in 2025, then plunged by 59.41% to -$364.7 million in 2026.
- According to Business Quant data, Enterprise Value over the past three periods registered -$364.7 million, -$228.8 million, and -$251.9 million for Q1 2026, Q4 2025, and Q3 2025 respectively.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) |
|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 138.51 Bn | 130.66 Bn | 2.84 Bn |
| 2 | Regeneron Pharmaceuticals | 85.24 Bn | 77.25 Bn | 3.93 Bn |
| 3 | Argenx Se | 63.46 Bn | 58.28 Bn | 1.37 Bn |
| 4 | Moderna | 57.89 Bn | 52.75 Bn | 52.00 Mn |
| 5 | Revolution Medicines | 44.02 Bn | 44.02 Bn | - |
| 6 | BeOne Medicines | 39.95 Bn | 34.85 Bn | 1.53 Bn |
| 7 | Alnylam Pharmaceuticals | 35.49 Bn | 32.19 Bn | 992.69 Mn |
| 8 | Royalty Pharma | 28.43 Bn | 27.59 Bn | - |
| 9 | Insmed | 27.39 Bn | 26.22 Bn | 358.27 Mn |
| 10 | Zymeworks | 2.15 Bn | 1.88 Bn | - |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 1.60 Bn |
| Mar 31, 2026 | 1.47 Bn |
| Dec 31, 2025 | 1.74 Bn |
| Sep 30, 2025 | 1.03 Bn |
| Jun 30, 2025 | 657.94 Mn |
| Mar 31, 2025 | 563.47 Mn |
| Dec 31, 2024 | 783.86 Mn |
| Sep 30, 2024 | 576.09 Mn |
| Jun 30, 2024 | 272.63 Mn |
| Mar 31, 2024 | 398.48 Mn |
| Dec 31, 2023 | 354.18 Mn |
| Sep 30, 2023 | 135.22 Mn |
| Jun 30, 2023 | 244.73 Mn |
| Mar 31, 2023 | 238.53 Mn |
| Dec 31, 2022 | 3.42 Mn |
| Sep 30, 2022 | 213.18 Mn |
| Jun 30, 2022 | 351.67 Mn |
| Mar 31, 2022 | 401.96 Mn |
| Dec 31, 2021 | 511.72 Mn |
| Sep 30, 2021 | 1.50 Bn |