Zymeworks (ZYME) Enterprise Value (2021 - 2026)
Zymeworks' (ZYME) quarterly Enterprise Value came in at -$364.7 million in Q1 2026, down 37.48% year-on-year from -$583.4 million in Q1 2025, and down 59.41% quarter-over-quarter from -$228.8 million in Q4 2025.
Zymeworks (ZYME) Enterprise Value (2021 - 2026) Analysis & Trends
Zymeworks has disclosed Enterprise Value across 6 years of filings, most recently posting -$364.7 million for Q1 2026.
- Enterprise Value for Q1 2026 came in at -$364.7 million, down 37.48% year-over-year; the trailing twelve-month figure through Mar 2026 was -$364.7 million (down 37.48% YoY), and the FY2025 annual result was -$228.8 million, down 1.34% from the prior year.
- Enterprise Value came in at -$364.7 million for Q1 2026 at Zymeworks, down from -$228.8 million in the prior quarter.
- In the past five years, Enterprise Value ranged from a high of -$166.2 million in Q3 2022 to a low of -$492.2 million in Q4 2022.
- The 5-year median for Enterprise Value is -$297.2 million (2024), against an average of -$306.6 million.
- Across the five-year window, Enterprise Value plunged 94.86% in 2022 and surged 39.68% in 2024, its largest moves.
- Zymeworks' Enterprise Value stood at -$492.2 million in 2022, then gained by 23.95% to -$374.3 million in 2023, then jumped by 39.68% to -$225.8 million in 2024, then declined by 1.34% to -$228.8 million in 2025, then plunged by 59.41% to -$364.7 million in 2026.
- The last three Enterprise Value figures came in at -$364.7 million (Q1 2026), -$228.8 million (Q4 2025), and -$251.9 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Enterprise Value (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | -32.30 Mn |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | -4.14 Mn |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -286.70 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | -18.44 Mn |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | -2.77 Mn |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | -7.20 Mn |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | -7.25 Bn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | -584.73 Mn |
| 10 | Zymeworks | 1.73 Bn | 1.36 Bn | - | -364.73 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -364.73 Mn |
| Dec 31, 2025 | -228.80 Mn |
| Sep 30, 2025 | -251.93 Mn |
| Jun 30, 2025 | -281.38 Mn |
| Mar 31, 2025 | -265.29 Mn |
| Dec 31, 2024 | -225.78 Mn |
| Sep 30, 2024 | -297.20 Mn |
| Jun 30, 2024 | -330.15 Mn |
| Mar 31, 2024 | -345.05 Mn |
| Dec 31, 2023 | -374.33 Mn |
| Sep 30, 2023 | -295.41 Mn |
| Jun 30, 2023 | -340.09 Mn |
| Mar 31, 2023 | -340.79 Mn |
| Dec 31, 2022 | -492.23 Mn |
| Sep 30, 2022 | -166.24 Mn |
| Dec 31, 2021 | -252.61 Mn |