Growth Metrics

Zymeworks (ZYME) EBT Margin (2021 - 2026)

Zymeworks recorded quarterly EBT Margin of 1924.96% in Q1 2026, down 16.72% quarter-over-quarter from 1649.26% in Q4 2025, and down 121076.0% year-over-year from N/an in Q1 2025.

Zymeworks' EBT Margin history runs 6 years deep, the most recent figure standing at 1924.96% for Q1 2026.

  • In Q1 2026, EBT Margin fell 121076.0% year-over-year to 1924.96%; the TTM figure through Mar 2026 stood at 132.19% (up 5217.0% YoY), while the FY2025 annual figure was 75.26%, up 7756.0% from the prior year.
  • EBT Margin came in at 1924.96% for Q1 2026 at Zymeworks, down from 1649.26% in the prior quarter.
  • In the past five years, EBT Margin ranged from a high of 98.6% in Q4 2022 to a low of 3794.31% in Q1 2022.
  • A 5-year average of 772.92% and a median of 314.84% in 2024 frame the typical range for EBT Margin.
  • Across the five-year window, EBT Margin soared 372977 bps in 2023 and slumped 159193 bps in 2025, its largest moves.
  • Zymeworks' EBT Margin stood at 98.6% in 2022, then slumped by 215 bps to 113.46% in 2023, then jumped by 49 bps to 57.33% in 2024, then plunged by 2777 bps to 1649.26% in 2025, then dropped by 17 bps to 1924.96% in 2026.
  • According to Business Quant data, EBT Margin over the past three periods registered 1924.96%, 1649.26%, and 73.06% for Q1 2026, Q4 2025, and Q3 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBT Margin (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -6.40%
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 41.95%
7 Evaxion A 62.56 Bn 62.54 Bn - -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 23.05%
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 18.99%
10 Zymeworks 1.84 Bn 1.47 Bn - -1,924.96%

Historic Data

Download Data 🔒
DateValue
Mar 31, 2026 -1,924.96%
Dec 31, 2025 -1,649.26%
Sep 30, 2025 -73.06%
Jun 30, 2025 4.37%
Mar 31, 2025 -714.19%
Dec 31, 2024 -57.33%
Sep 30, 2024 -185.15%
Jun 30, 2024 -470.23%
Mar 31, 2024 -314.84%
Dec 31, 2023 -113.46%
Sep 30, 2023 -167.07%
Jun 30, 2023 -706.91%
Mar 31, 2023 -64.54%
Dec 31, 2022 98.60%
Sep 30, 2022 -1,819.65%
Jun 30, 2022 -1,187.58%
Mar 31, 2022 -3,794.31%
Dec 31, 2021 -506.54%
Sep 30, 2021 -1,360.98%