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Asset Utilization RatioAssets AverageEBIT MarginEBITDA MarginEBT MarginEnterprise ValueEquity AverageEquity RatioFCF MarginInvested CapitalNet MarginOperating MarginReturn on AssetsReturn on Capital EmployedReturn on EquityReturn on Invested CapitalReturn on Sales

Zymeworks (ZYME) EBITDA Margin (2021 - 2025)

Zymeworks' EBITDA Margin history spans 5 years, with the latest figure at 1639.68% for Q4 2025.

  • On a quarterly basis, EBITDA Margin fell 156086.0% to 1639.68% in Q4 2025 year-over-year; TTM through Dec 2025 was 101.15%, a 8797.0% increase, with the full-year FY2025 number at 75.74%, up 8552.0% from a year prior.
  • EBITDA Margin hit 1639.68% in Q4 2025 for Zymeworks, down from 77.25% in the prior quarter.
  • Over the last five years, EBITDA Margin for ZYME hit a ceiling of 95.21% in Q4 2022 and a floor of 3790.45% in Q1 2022.
  • Historically, EBITDA Margin has averaged 729.06% across 5 years, with a median of 400.04% in 2024.
  • Biggest five-year swings in EBITDA Margin: soared 372402bps in 2023 and later crashed -156086bps in 2025.
  • Tracing ZYME's EBITDA Margin over 5 years: stood at 489.4% in 2021, then surged by 119bps to 95.21% in 2022, then plummeted by -179bps to 75.55% in 2023, then fell by -4bps to 78.82% in 2024, then tumbled by -1980bps to 1639.68% in 2025.
  • Business Quant data shows EBITDA Margin for ZYME at 1639.68% in Q4 2025, 77.25% in Q3 2025, and 4.89% in Q2 2025.