Zymeworks (ZYME) EBIT Margin (2021 - 2026)
Zymeworks' (ZYME) quarterly EBIT Margin came in at 1956.73% in Q1 2026, down 113050.0% year-on-year from N/an in Q1 2025, and down 11.46% quarter-over-quarter from 1755.55% in Q4 2025.
Zymeworks (ZYME) EBIT Margin (2021 - 2026) Analysis & Trends
Zymeworks has disclosed EBIT Margin across 6 years of filings, most recently posting 1956.73% for Q1 2026.
- EBIT Margin for Q1 2026 came in at 1956.73%, down 113050.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 145.02% (up 6988.0% YoY), and the FY2025 annual result was 87.34%, up 9235.0% from the prior year.
- EBIT Margin came in at 1956.73% for Q1 2026 at Zymeworks, down from 1755.55% in the prior quarter.
- In the past five years, EBIT Margin ranged from a high of 98.28% in Q4 2022 to a low of 3793.63% in Q1 2022.
- The 5-year median for EBIT Margin is 376.89% (2024), against an average of 813.81%.
- Across the five-year window, EBIT Margin jumped 371695 bps in 2023 and slumped 168395 bps in 2025, its largest moves.
- Zymeworks' EBIT Margin stood at 98.28% in 2022, then sank by 241 bps to 138.37% in 2023, then soared by 48 bps to 71.6% in 2024, then tumbled by 2352 bps to 1755.55% in 2025, then fell by 11 bps to 1956.73% in 2026.
- The last three EBIT Margin figures came in at 1956.73% (Q1 2026), 1755.55% (Q4 2025), and 88.44% (Q3 2025), per Business Quant data.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBIT Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | - |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -6.43% |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | - |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 38.10% |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | - |
| 10 | Zymeworks | 1.73 Bn | 1.36 Bn | - | -1,956.73% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -1,956.73% |
| Dec 31, 2025 | -1,755.55% |
| Sep 30, 2025 | -88.44% |
| Jun 30, 2025 | -1.38% |
| Mar 31, 2025 | -826.23% |
| Dec 31, 2024 | -71.60% |
| Sep 30, 2024 | -213.78% |
| Jun 30, 2024 | -536.08% |
| Mar 31, 2024 | -376.89% |
| Dec 31, 2023 | -138.37% |
| Sep 30, 2023 | -201.36% |
| Jun 30, 2023 | -772.84% |
| Mar 31, 2023 | -76.68% |
| Dec 31, 2022 | 98.28% |
| Sep 30, 2022 | -1,914.03% |
| Jun 30, 2022 | -1,209.54% |
| Mar 31, 2022 | -3,793.63% |
| Dec 31, 2021 | -510.61% |
| Sep 30, 2021 | -1,387.12% |