Zymeworks (ZYME) Change in Cash (2021 - 2026)

Zymeworks' (ZYME) quarterly Change in Cash came in at $203.1 million in Q1 2026, up 1910.94% year-on-year from $10.1 million in Q1 2025, and up 957.9% quarter-over-quarter from -$23.7 million in Q4 2025.

Zymeworks (ZYME) Change in Cash (2021 - 2026) Analysis & Trends

Zymeworks has disclosed Change in Cash across 6 years of filings, most recently posting $203.1 million for Q1 2026.

  • Change in Cash for Q1 2026 came in at $203.1 million, up 1910.94% year-over-year; the trailing twelve-month figure through Mar 2026 was $168.1 million (up 535.32% YoY), and the FY2025 annual result was -$24.9 million, up 72.72% from the prior year.
  • Change in Cash came in at $203.1 million for Q1 2026 at Zymeworks, up from -$23.7 million in the prior quarter.
  • In the past five years, Change in Cash ranged from a high of $304.8 million in Q4 2022 to a low of -$219.3 million in Q1 2023.
  • The 5-year median for Change in Cash is -$33.4 million (2025), against an average of $2.5 million.
  • Across the five-year window, Change in Cash plunged 397.8% in 2023 and jumped 1910.94% in 2026, its largest moves.
  • Zymeworks' Change in Cash stood at $304.8 million in 2022, then plunged by 79.26% to $63.2 million in 2023, then slumped by 188.97% to -$56.3 million in 2024, then surged by 57.91% to -$23.7 million in 2025, then jumped by 957.9% to $203.1 million in 2026.
  • The last three Change in Cash figures came in at $203.1 million (Q1 2026), -$23.7 million (Q4 2025), and -$33.4 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Change in Cash (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - 2.44 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 623.00 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -2.44 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 417.10 Mn
9 Abivax 91.96 Bn 91.96 Bn - -45.97 Mn
10 Zymeworks 1.73 Bn 1.36 Bn - 203.13 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 203.13 Mn
Dec 31, 2025 -23.68 Mn
Sep 30, 2025 -33.42 Mn
Jun 30, 2025 22.05 Mn
Mar 31, 2025 10.10 Mn
Dec 31, 2024 -56.25 Mn
Sep 30, 2024 51.39 Mn
Jun 30, 2024 -43.85 Mn
Mar 31, 2024 -42.74 Mn
Dec 31, 2023 63.23 Mn
Sep 30, 2023 -47.77 Mn
Jun 30, 2023 -39.48 Mn
Mar 31, 2023 -219.33 Mn
Dec 31, 2022 304.83 Mn
Sep 30, 2022 -102.57 Mn
Jun 30, 2022 -76.87 Mn
Mar 31, 2022 73.65 Mn
Dec 31, 2021 -51.57 Mn