Zymeworks (ZYME) Change in Cash (2021 - 2026)
Zymeworks recorded quarterly Change in Cash of $203.1 million in Q1 2026, up 957.9% quarter-over-quarter from -$23.7 million in Q4 2025, and up 1910.94% year-over-year from $10.1 million in Q1 2025.
Zymeworks' Change in Cash history runs 6 years deep, the most recent figure standing at $203.1 million for Q1 2026.
- In Q1 2026, Change in Cash rose 1910.94% year-over-year to $203.1 million; the TTM figure through Mar 2026 stood at $168.1 million (up 535.32% YoY), while the FY2025 annual figure was -$24.9 million, up 72.72% from the prior year.
- Change in Cash came in at $203.1 million for Q1 2026 at Zymeworks, up from -$23.7 million in the prior quarter.
- In the past five years, Change in Cash ranged from a high of $304.8 million in Q4 2022 to a low of -$219.3 million in Q1 2023.
- A 5-year average of $2.5 million and a median of -$33.4 million in 2025 frame the typical range for Change in Cash.
- Across the five-year window, Change in Cash tumbled 397.8% in 2023 and surged 1910.94% in 2026, its largest moves.
- Zymeworks' Change in Cash stood at $304.8 million in 2022, then tumbled by 79.26% to $63.2 million in 2023, then sank by 188.97% to -$56.3 million in 2024, then soared by 57.91% to -$23.7 million in 2025, then surged by 957.9% to $203.1 million in 2026.
- According to Business Quant data, Change in Cash over the past three periods registered $203.1 million, -$23.7 million, and -$33.4 million for Q1 2026, Q4 2025, and Q3 2025 respectively.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Change in Cash (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 961,148.99 Bn | 961,148.98 Bn | - | 2.44 Mn |
| 2 | Alterity Therapeutics | 744,933.29 Bn | 744,933.26 Bn | - | - |
| 3 | Legend Biotech | 2,540.00 Bn | 2,539.71 Bn | 242.10 Mn | 623.00 Mn |
| 4 | Nanobiotix | 2,199.85 Bn | 2,199.78 Bn | - | - |
| 5 | Akari Therapeutics | 1,635.88 Bn | 1,635.88 Bn | - | -2.44 Mn |
| 6 | Vertex Pharmaceuticals | 111.32 Bn | 104.07 Bn | 2.59 Bn | 417.10 Mn |
| 7 | Evaxion A | 62.56 Bn | 62.54 Bn | - | - |
| 8 | Regeneron Pharmaceuticals | 62.55 Bn | 53.79 Bn | 3.31 Bn | -153.10 Mn |
| 9 | Alnylam Pharmaceuticals | 39.57 Bn | 36.56 Bn | 959.66 Mn | 53.61 Mn |
| 10 | Zymeworks | 1.84 Bn | 1.47 Bn | - | 203.13 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 203.13 Mn |
| Dec 31, 2025 | -23.68 Mn |
| Sep 30, 2025 | -33.42 Mn |
| Jun 30, 2025 | 22.05 Mn |
| Mar 31, 2025 | 10.10 Mn |
| Dec 31, 2024 | -56.25 Mn |
| Sep 30, 2024 | 51.39 Mn |
| Jun 30, 2024 | -43.85 Mn |
| Mar 31, 2024 | -42.74 Mn |
| Dec 31, 2023 | 63.23 Mn |
| Sep 30, 2023 | -47.77 Mn |
| Jun 30, 2023 | -39.48 Mn |
| Mar 31, 2023 | -219.33 Mn |
| Dec 31, 2022 | 304.83 Mn |
| Sep 30, 2022 | -102.57 Mn |
| Jun 30, 2022 | -76.87 Mn |
| Mar 31, 2022 | 73.65 Mn |
| Dec 31, 2021 | -51.57 Mn |