Zymeworks (ZYME) Change in Cash (2021 - 2026)
Zymeworks' (ZYME) quarterly Change in Cash came in at $203.1 million in Q1 2026, up 1910.94% year-on-year from $10.1 million in Q1 2025, and up 957.9% quarter-over-quarter from -$23.7 million in Q4 2025.
Zymeworks (ZYME) Change in Cash (2021 - 2026) Analysis & Trends
Zymeworks has disclosed Change in Cash across 6 years of filings, most recently posting $203.1 million for Q1 2026.
- Change in Cash for Q1 2026 came in at $203.1 million, up 1910.94% year-over-year; the trailing twelve-month figure through Mar 2026 was $168.1 million (up 535.32% YoY), and the FY2025 annual result was -$24.9 million, up 72.72% from the prior year.
- Change in Cash came in at $203.1 million for Q1 2026 at Zymeworks, up from -$23.7 million in the prior quarter.
- In the past five years, Change in Cash ranged from a high of $304.8 million in Q4 2022 to a low of -$219.3 million in Q1 2023.
- The 5-year median for Change in Cash is -$33.4 million (2025), against an average of $2.5 million.
- Across the five-year window, Change in Cash plunged 397.8% in 2023 and jumped 1910.94% in 2026, its largest moves.
- Zymeworks' Change in Cash stood at $304.8 million in 2022, then plunged by 79.26% to $63.2 million in 2023, then slumped by 188.97% to -$56.3 million in 2024, then surged by 57.91% to -$23.7 million in 2025, then jumped by 957.9% to $203.1 million in 2026.
- The last three Change in Cash figures came in at $203.1 million (Q1 2026), -$23.7 million (Q4 2025), and -$33.4 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Change in Cash (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | 2.44 Mn |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | 623.00 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | -2.44 Mn |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 417.10 Mn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | -45.97 Mn |
| 10 | Zymeworks | 1.73 Bn | 1.36 Bn | - | 203.13 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 203.13 Mn |
| Dec 31, 2025 | -23.68 Mn |
| Sep 30, 2025 | -33.42 Mn |
| Jun 30, 2025 | 22.05 Mn |
| Mar 31, 2025 | 10.10 Mn |
| Dec 31, 2024 | -56.25 Mn |
| Sep 30, 2024 | 51.39 Mn |
| Jun 30, 2024 | -43.85 Mn |
| Mar 31, 2024 | -42.74 Mn |
| Dec 31, 2023 | 63.23 Mn |
| Sep 30, 2023 | -47.77 Mn |
| Jun 30, 2023 | -39.48 Mn |
| Mar 31, 2023 | -219.33 Mn |
| Dec 31, 2022 | 304.83 Mn |
| Sep 30, 2022 | -102.57 Mn |
| Jun 30, 2022 | -76.87 Mn |
| Mar 31, 2022 | 73.65 Mn |
| Dec 31, 2021 | -51.57 Mn |