Balance Sheet
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Zymeworks (ZYME) Change in Cash (2021 - 2025)

Zymeworks' Change in Cash history spans 5 years, with the latest figure at -$23.7 million for Q4 2025.

  • On a quarterly basis, Change in Cash rose 57.91% to -$23.7 million in Q4 2025 year-over-year; TTM through Dec 2025 was -$24.9 million, a 72.72% increase, with the full-year FY2025 number at -$24.9 million, up 72.72% from a year prior.
  • Change in Cash hit -$23.7 million in Q4 2025 for Zymeworks, up from -$33.4 million in the prior quarter.
  • Over the last five years, Change in Cash for ZYME hit a ceiling of $304.8 million in Q4 2022 and a floor of -$219.3 million in Q1 2023.
  • Historically, Change in Cash has averaged -$12.5 million across 5 years, with a median of -$39.5 million in 2023.
  • Biggest five-year swings in Change in Cash: skyrocketed 691.08% in 2022 and later tumbled 397.8% in 2023.
  • Tracing ZYME's Change in Cash over 5 years: stood at -$51.6 million in 2021, then skyrocketed by 691.08% to $304.8 million in 2022, then crashed by 79.26% to $63.2 million in 2023, then plummeted by 188.97% to -$56.3 million in 2024, then soared by 57.91% to -$23.7 million in 2025.
  • Business Quant data shows Change in Cash for ZYME at -$23.7 million in Q4 2025, -$33.4 million in Q3 2025, and $22.0 million in Q2 2025.