Zymeworks (ZYME) Change in Cash (2021 - 2026)

Zymeworks (ZYME) reported Change in Cash of $203.1 million for Q1 2026, up 1910.94% on a YoY basis from $10.1 million in Q1 2025, and up 957.9% sequentially from -$23.7 million in Q4 2025.

Zymeworks (ZYME) Change in Cash (2021 - 2026) Analysis & Trends

Zymeworks (ZYME) has 6 years of Change in Cash data on file, last reported at $203.1 million in Q1 2026.

  • For the quarter ending Q1 2026, Change in Cash rose 1910.94% year-over-year to $203.1 million; the trailing twelve-month figure through Mar 2026 stood at $168.1 million (up 535.32% YoY), and the FY2025 full-year result was -$24.9 million, up 72.72% from the prior year.
  • Change in Cash climbed to $203.1 million in Q1 2026, from -$23.7 million in the prior quarter.
  • In the past five years, Change in Cash ranged from a high of $304.8 million in Q4 2022 to a low of -$219.3 million in Q1 2023.
  • A 5-year average of $2.5 million and a median of -$33.4 million in 2025 frame the typical range for Change in Cash.
  • Across the five-year window, Change in Cash slumped 397.8% in 2023 and jumped 1910.94% in 2026, its largest moves.
  • Tracing ZYME's Change in Cash over 5 years: stood at $304.8 million in 2022, then sank by 79.26% to $63.2 million in 2023, then tumbled by 188.97% to -$56.3 million in 2024, then jumped by 57.91% to -$23.7 million in 2025, then soared by 957.9% to $203.1 million in 2026.
  • Business Quant data shows ZYME's Change in Cash at $203.1 million in Q1 2026, -$23.7 million in Q4 2025, and -$33.4 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Change in Cash (Qtr)
1 Oculis Holding AG 66,621.14 Bn 66,620.85 Bn - -22.03 Mn
2 Nanobiotix 1,915.18 Bn 1,915.11 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -2.44 Mn
4 BeOne Medicines 471.27 Bn 466.48 Bn 1.35 Bn 243.78 Mn
5 Vertex Pharmaceuticals 121.81 Bn 114.57 Bn 2.59 Bn 417.10 Mn
6 Regeneron Pharmaceuticals 69.58 Bn 60.82 Bn 3.31 Bn -153.10 Mn
7 Belite Bio 62.72 Bn 62.72 Bn - -
8 Argenx Se 55.51 Bn 50.33 Bn 1.41 Bn -
9 Revolution Medicines 37.35 Bn 37.35 Bn - 57.19 Mn
10 Zymeworks 1.73 Bn 1.36 Bn - 203.13 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 203.13 Mn
Dec 31, 2025 -23.68 Mn
Sep 30, 2025 -33.42 Mn
Jun 30, 2025 22.05 Mn
Mar 31, 2025 10.10 Mn
Dec 31, 2024 -56.25 Mn
Sep 30, 2024 51.39 Mn
Jun 30, 2024 -43.85 Mn
Mar 31, 2024 -42.74 Mn
Dec 31, 2023 63.23 Mn
Sep 30, 2023 -47.77 Mn
Jun 30, 2023 -39.48 Mn
Mar 31, 2023 -219.33 Mn
Dec 31, 2022 304.83 Mn
Sep 30, 2022 -102.57 Mn
Jun 30, 2022 -76.87 Mn
Mar 31, 2022 73.65 Mn
Dec 31, 2021 -51.57 Mn