Zymeworks (ZYME) Change in Cash (2021 - 2026)
Zymeworks (ZYME) posted Change in Cash of $203.1 million for Q1 2026, up 957.9% sequentially from -$23.7 million in Q4 2025, and up 1910.94% YoY from $10.1 million in Q1 2025.
Analysis
Zymeworks (ZYME) Change in Cash (2021 - 2026) Analysis & Trends
Zymeworks has reported Change in Cash for 6 years, with the latest figure at $203.1 million in Q1 2026.
- Quarterly Change in Cash rose 1910.94% year-over-year to $203.1 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $168.1 million (up 535.32% YoY) and the FY2025 annual result came in at -$24.9 million, up 72.72% from the prior year.
- Change in Cash climbed to $203.1 million in Q1 2026 per ZYME's latest filing, from -$23.7 million in the prior quarter.
- Over five years, Change in Cash peaked at $304.8 million in Q4 2022 and troughed at -$219.3 million in Q1 2023.
- A 5-year average of $2.5 million and a median of -$33.4 million in 2025 frame the typical range for Change in Cash.
- The sharpest annual moves came in 2023 and 2026: Change in Cash plunged 397.8% in 2023, then soared 1910.94% in 2026.
- Over 5 years, Change in Cash stood at $304.8 million in 2022, then plunged by 79.26% to $63.2 million in 2023, then slumped by 188.97% to -$56.3 million in 2024, then jumped by 57.91% to -$23.7 million in 2025, then soared by 957.9% to $203.1 million in 2026.
- According to Business Quant data, Change in Cash over the past three periods registered $203.1 million, -$23.7 million, and -$33.4 million for Q1 2026, Q4 2025, and Q3 2025 respectively.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Change in Cash (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 138.43 Bn | 130.58 Bn | 2.84 Bn | 649.20 Mn |
| 2 | Regeneron Pharmaceuticals | 85.18 Bn | 77.19 Bn | 3.93 Bn | -504.60 Mn |
| 3 | Argenx Se | 63.34 Bn | 58.15 Bn | 1.37 Bn | - |
| 4 | Moderna | 57.98 Bn | 52.85 Bn | 52.00 Mn | -185.00 Mn |
| 5 | Revolution Medicines | 43.98 Bn | 43.98 Bn | - | 374.50 Mn |
| 6 | BeOne Medicines | 39.92 Bn | 34.82 Bn | 1.53 Bn | 427.25 Mn |
| 7 | Alnylam Pharmaceuticals | 35.42 Bn | 32.11 Bn | 992.69 Mn | -2.94 Mn |
| 8 | Royalty Pharma | 28.42 Bn | 27.58 Bn | - | 225.59 Mn |
| 9 | Insmed | 27.36 Bn | 26.20 Bn | 358.27 Mn | -37.42 Mn |
| 10 | Zymeworks | 2.15 Bn | 1.88 Bn | - | -64.87 Mn |
Historic Data
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Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -64.87 Mn |
| Mar 31, 2026 | 203.13 Mn |
| Dec 31, 2025 | -23.68 Mn |
| Sep 30, 2025 | -33.42 Mn |
| Jun 30, 2025 | 22.05 Mn |
| Mar 31, 2025 | 10.10 Mn |
| Dec 31, 2024 | -56.25 Mn |
| Sep 30, 2024 | 51.39 Mn |
| Jun 30, 2024 | -43.85 Mn |
| Mar 31, 2024 | -42.74 Mn |
| Dec 31, 2023 | 63.23 Mn |
| Sep 30, 2023 | -47.77 Mn |
| Jun 30, 2023 | -39.48 Mn |
| Mar 31, 2023 | -219.33 Mn |
| Dec 31, 2022 | 304.83 Mn |
| Sep 30, 2022 | -102.57 Mn |
| Jun 30, 2022 | -76.87 Mn |
| Mar 31, 2022 | 73.65 Mn |
| Dec 31, 2021 | -51.57 Mn |