Growth Metrics

Zymeworks (ZYME) Cash from Operations (2021 - 2026)

Zymeworks recorded quarterly Cash from Operations of 45718000.0 in Q1 2026, down 345.64% quarter-over-quarter from 10259000.0 in Q4 2025, and down 1241.88% year-over-year from 4003732.93 in Q1 2025.

Zymeworks' Cash from Operations history runs 6 years deep, the most recent figure standing at 45718000.0 for Q1 2026.

  • In Q1 2026, Cash from Operations fell 1241.88% year-over-year to 45718000.0; the TTM figure through Mar 2026 stood at 75316000.0 (up 0.63% YoY), while the FY2025 annual figure was 33005000.0, up 70.01% from the prior year.
  • Cash from Operations came in at 45718000.0 for Q1 2026 at Zymeworks, down from 10259000.0 in the prior quarter.
  • In the past five years, Cash from Operations ranged from a high of 327360000.0 in Q4 2022 to a low of 83191000.0 in Q1 2023.
  • A 5-year average of 9588000.0 and a median of 31412000.0 in 2025 frame the typical range for Cash from Operations.
  • Across the five-year window, Cash from Operations surged 748.12% in 2022 and tumbled 1241.88% in 2026, its largest moves.
  • Zymeworks' Cash from Operations stood at 327360000.0 in 2022, then sank by 95.74% to 13933000.0 in 2023, then plunged by 397.93% to 41510000.0 in 2024, then surged by 75.29% to 10259000.0 in 2025, then plunged by 345.64% to 45718000.0 in 2026.
  • According to Business Quant data, Cash from Operations over the past three periods registered 45718000.0, 10259000.0, and 31412000.0 for Q1 2026, Q4 2025, and Q3 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Cash from Operations (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -1.67 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -12.20 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -2.49 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 1.43 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 1.08 Bn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 70.50 Mn
10 Zymeworks 1.84 Bn 1.47 Bn - -45.72 Mn

Historic Data

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DateValue
Mar 31, 2026 -45.72 Mn
Mar 31, 2026 -45.72 Mn
Dec 31, 2025 -10.26 Mn
Dec 31, 2025 -10.26 Mn
Sep 30, 2025 -31.41 Mn
Sep 30, 2025 -31.41 Mn
Jun 30, 2025 12.07 Mn
Jun 30, 2025 12.07 Mn
Mar 31, 2025 -3.41 Mn
Mar 31, 2025 -3.41 Mn
Dec 31, 2024 -41.51 Mn
Dec 31, 2024 -41.51 Mn
Sep 30, 2024 -5.88 Mn
Sep 30, 2024 -5.88 Mn
Jun 30, 2024 -24.99 Mn
Jun 30, 2024 -24.99 Mn
Mar 31, 2024 -37.68 Mn
Mar 31, 2024 -37.68 Mn
Dec 31, 2023 13.93 Mn
Dec 31, 2023 13.93 Mn
Sep 30, 2023 -42.67 Mn
Sep 30, 2023 -42.67 Mn
Jun 30, 2023 -6.40 Mn
Jun 30, 2023 -6.40 Mn
Mar 31, 2023 -83.19 Mn
Mar 31, 2023 -83.19 Mn
Dec 31, 2022 327.36 Mn
Dec 31, 2022 327.36 Mn
Sep 30, 2022 -73.02 Mn
Sep 30, 2022 -73.02 Mn
Jun 30, 2022 -54.82 Mn
Jun 30, 2022 -54.82 Mn
Mar 31, 2022 -55.41 Mn
Mar 31, 2022 -55.41 Mn
Dec 31, 2021 -50.51 Mn
Dec 31, 2021 -50.51 Mn