Zevra Therapeutics (ZVRA) EBITDA Margin (2019 - 2026)

Zevra Therapeutics (ZVRA) reported EBITDA Margin of 144.05% for Q1 2026, up 17033.0% on a YoY basis from N/an in Q1 2025, and up 428.41% quarter-over-quarter from 27.26% in Q4 2025.

Zevra Therapeutics (ZVRA) EBITDA Margin (2019 - 2026) Analysis & Trends

Zevra Therapeutics has reported EBITDA Margin for 8 years, with the latest figure at 144.05% in Q1 2026.

  • For the quarter ending Q1 2026, EBITDA Margin rose 17033.0% year-over-year to 144.05%; the trailing twelve-month figure through Mar 2026 stood at 4.44% (up 17300.0% YoY), and the FY2025 full-year result was 58.93%, up 30869.0% from the prior year.
  • EBITDA Margin for Q1 2026 stood at 144.05%, up from 27.26% in the prior quarter.
  • The five-year high for EBITDA Margin was 144.05% in Q1 2026, with the low at 739.0% in Q3 2024.
  • Historically, EBITDA Margin has averaged 225.05% across 5 years, with a median of 117.31% in 2023.
  • Annual changes were most pronounced in 2023 — EBITDA Margin plunged 52643 bps — and 2025, when it jumped 75489 bps.
  • Zevra Therapeutics' EBITDA Margin stood at 424.67% in 2022, then soared by 72 bps to 117.31% in 2023, then declined by 9 bps to 128.34% in 2024, then soared by 121 bps to 27.26% in 2025, then jumped by 428 bps to 144.05% in 2026.
  • The last three EBITDA Margin figures came in at 144.05% (Q1 2026), 27.26% (Q4 2025), and 15.9% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA Margin (Qtr)
1 Alterity Therapeutics 719,706.53 Bn 719,706.50 Bn - -
2 Belite Bio 55,800.00 Bn 55,800.00 Bn - -
3 Quantum Biopharma 18,182.30 Bn 18,182.29 Bn - -
4 Legend Biotech 3,154.00 Bn 3,153.71 Bn 242.10 Mn -6.43%
5 Akari Therapeutics 1,844.30 Bn 1,844.29 Bn - -
6 Evaxion A 1,567.96 Bn 1,567.94 Bn - -
7 Psyence Biomedical 251.43 Bn 251.42 Bn - -
8 Vertex Pharmaceuticals 112.56 Bn 105.31 Bn 2.59 Bn 38.10%
9 Abivax 94.37 Bn 94.37 Bn - -
10 Zevra Therapeutics 704.96 Mn 504.34 Mn 34.30 Mn 144.05%

Historic Data

Download Data
DateValue
Mar 31, 2026 144.05%
Dec 31, 2025 27.26%
Sep 30, 2025 15.90%
Jun 30, 2025 -274.48%
Mar 31, 2025 -26.28%
Dec 31, 2024 -128.34%
Sep 30, 2024 -739.00%
Jun 30, 2024 -540.80%
Mar 31, 2024 -602.53%
Dec 31, 2023 -117.31%
Sep 30, 2023 -530.71%
Jun 30, 2023 -73.81%
Mar 31, 2023 -404.00%
Dec 31, 2022 -424.67%
Sep 30, 2022 -4.28%
Jun 30, 2022 -100.00%
Mar 31, 2022 -46.89%
Dec 31, 2021 -110.07%
Sep 30, 2021 -113.08%
Jun 30, 2021 48.67%